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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
PRODH2
Full Name:
Probable proline dehydrogenase 2
Alias:
HSPOX1; proline dehydrogenase (oxidase) 2
Type:
Oxidoreductase; Mitochondrial; Amino Acid Metabolism - arginine and proline; EC 1.5.99.8
Mass (Da):
58870
Number AA:
UniProt ID:
Q9UF12
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
GO:0004657
PhosphoSite+
KinaseNET
Biological Process:
GO:0006537
GO:0055114
GO:0006562
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S9
S
P
R
V
V
S
N
S
S
V
L
A
S
Q
S
Site 2
S14
S
N
S
S
V
L
A
S
Q
S
V
G
I
T
N
Site 3
T34
S
N
V
F
N
N
T
T
A
F
P
I
L
R
G
Site 4
S72
N
L
P
W
C
G
G
S
Q
G
P
R
M
L
R
Site 5
S86
R
T
C
Y
V
L
C
S
Q
A
G
P
P
S
R
Site 6
S92
C
S
Q
A
G
P
P
S
R
G
W
Q
S
L
S
Site 7
S97
P
P
S
R
G
W
Q
S
L
S
F
D
G
G
A
Site 8
S99
S
R
G
W
Q
S
L
S
F
D
G
G
A
F
H
Site 9
S139
G
L
L
L
Q
A
W
S
R
R
L
L
G
S
R
Site 10
S145
W
S
R
R
L
L
G
S
R
L
S
G
A
F
L
Site 11
S195
P
T
E
E
E
P
D
S
A
A
K
S
G
E
A
Site 12
S199
E
P
D
S
A
A
K
S
G
E
A
W
Y
E
G
Site 13
Y204
A
K
S
G
E
A
W
Y
E
G
N
L
G
A
M
Site 14
S251
R
L
C
K
E
L
A
S
W
V
R
R
P
G
A
Site 15
S259
W
V
R
R
P
G
A
S
L
E
L
S
P
E
R
Site 16
S263
P
G
A
S
L
E
L
S
P
E
R
L
A
E
A
Site 17
S273
R
L
A
E
A
M
D
S
G
Q
N
L
Q
V
S
Site 18
S293
Q
N
Q
H
L
R
A
S
L
S
R
L
H
R
V
Site 19
S295
Q
H
L
R
A
S
L
S
R
L
H
R
V
A
Q
Site 20
Y303
R
L
H
R
V
A
Q
Y
A
R
A
Q
H
V
R
Site 21
S337
A
L
A
V
R
W
N
S
P
G
E
G
G
P
W
Site 22
T356
Y
Q
A
C
L
K
D
T
F
E
R
L
G
R
D
Site 23
Y383
V
K
L
V
R
G
A
Y
L
D
K
E
R
A
V
Site 24
T400
L
H
G
M
E
D
P
T
Q
P
D
Y
E
A
T
Site 25
Y404
E
D
P
T
Q
P
D
Y
E
A
T
S
Q
S
Y
Site 26
S408
Q
P
D
Y
E
A
T
S
Q
S
Y
S
R
C
L
Site 27
S410
D
Y
E
A
T
S
Q
S
Y
S
R
C
L
E
L
Site 28
S412
E
A
T
S
Q
S
Y
S
R
C
L
E
L
M
L
Site 29
T420
R
C
L
E
L
M
L
T
H
V
A
R
H
G
P
Site 30
S440
V
A
S
H
N
E
E
S
V
R
Q
A
T
K
R
Site 31
T445
E
E
S
V
R
Q
A
T
K
R
M
W
E
L
G
Site 32
Y497
S
L
E
E
V
I
P
Y
L
I
R
R
A
Q
E
Site 33
S520
R
R
E
Q
E
L
L
S
Q
E
L
W
R
R
L
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation