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Updated November 2019
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Protein Info
Short Name:
DKFZP434B061
Full Name:
Uncharacterized protein DKFZP434B061
Alias:
DKFZp434b061; Ym012
Type:
Uncharacterized protein
Mass (Da):
59412
Number AA:
564
UniProt ID:
Q9UF83
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S5
_
_
_
M
R
R
P
S
T
A
S
L
T
R
T
Site 2
T6
_
_
M
R
R
P
S
T
A
S
L
T
R
T
P
Site 3
S8
M
R
R
P
S
T
A
S
L
T
R
T
P
S
R
Site 4
T10
R
P
S
T
A
S
L
T
R
T
P
S
R
A
S
Site 5
T12
S
T
A
S
L
T
R
T
P
S
R
A
S
P
T
Site 6
S14
A
S
L
T
R
T
P
S
R
A
S
P
T
R
M
Site 7
S17
T
R
T
P
S
R
A
S
P
T
R
M
P
S
R
Site 8
T19
T
P
S
R
A
S
P
T
R
M
P
S
R
A
S
Site 9
S23
A
S
P
T
R
M
P
S
R
A
S
L
K
M
T
Site 10
S26
T
R
M
P
S
R
A
S
L
K
M
T
P
F
R
Site 11
T30
S
R
A
S
L
K
M
T
P
F
R
A
S
L
T
Site 12
S35
K
M
T
P
F
R
A
S
L
T
K
M
E
S
T
Site 13
T37
T
P
F
R
A
S
L
T
K
M
E
S
T
A
L
Site 14
S52
L
R
T
L
P
R
A
S
L
M
R
T
P
T
R
Site 15
T56
P
R
A
S
L
M
R
T
P
T
R
A
S
L
M
Site 16
T58
A
S
L
M
R
T
P
T
R
A
S
L
M
R
T
Site 17
S61
M
R
T
P
T
R
A
S
L
M
R
T
P
P
R
Site 18
T65
T
R
A
S
L
M
R
T
P
P
R
A
S
P
T
Site 19
S70
M
R
T
P
P
R
A
S
P
T
R
K
P
P
R
Site 20
S79
T
R
K
P
P
R
A
S
P
R
T
P
S
R
A
Site 21
T82
P
P
R
A
S
P
R
T
P
S
R
A
S
P
T
Site 22
S84
R
A
S
P
R
T
P
S
R
A
S
P
T
R
R
Site 23
S87
P
R
T
P
S
R
A
S
P
T
R
R
L
P
R
Site 24
S96
T
R
R
L
P
R
A
S
P
M
G
S
P
H
R
Site 25
S100
P
R
A
S
P
M
G
S
P
H
R
A
S
P
M
Site 26
S105
M
G
S
P
H
R
A
S
P
M
R
T
P
P
R
Site 27
T109
H
R
A
S
P
M
R
T
P
P
R
A
S
P
T
Site 28
S114
M
R
T
P
P
R
A
S
P
T
G
T
P
S
T
Site 29
T116
T
P
P
R
A
S
P
T
G
T
P
S
T
A
S
Site 30
T118
P
R
A
S
P
T
G
T
P
S
T
A
S
P
T
Site 31
S120
A
S
P
T
G
T
P
S
T
A
S
P
T
G
T
Site 32
T121
S
P
T
G
T
P
S
T
A
S
P
T
G
T
P
Site 33
S123
T
G
T
P
S
T
A
S
P
T
G
T
P
S
S
Site 34
T125
T
P
S
T
A
S
P
T
G
T
P
S
S
A
S
Site 35
T127
S
T
A
S
P
T
G
T
P
S
S
A
S
P
T
Site 36
S129
A
S
P
T
G
T
P
S
S
A
S
P
T
G
T
Site 37
S130
S
P
T
G
T
P
S
S
A
S
P
T
G
T
P
Site 38
S132
T
G
T
P
S
S
A
S
P
T
G
T
P
P
R
Site 39
T134
T
P
S
S
A
S
P
T
G
T
P
P
R
A
S
Site 40
T136
S
S
A
S
P
T
G
T
P
P
R
A
S
P
T
Site 41
S141
T
G
T
P
P
R
A
S
P
T
G
T
P
P
R
Site 42
T143
T
P
P
R
A
S
P
T
G
T
P
P
R
A
W
Site 43
T145
P
R
A
S
P
T
G
T
P
P
R
A
W
A
T
Site 44
T152
T
P
P
R
A
W
A
T
R
S
P
S
T
A
S
Site 45
S154
P
R
A
W
A
T
R
S
P
S
T
A
S
L
T
Site 46
S156
A
W
A
T
R
S
P
S
T
A
S
L
T
R
T
Site 47
S159
T
R
S
P
S
T
A
S
L
T
R
T
P
S
R
Site 48
T161
S
P
S
T
A
S
L
T
R
T
P
S
R
A
S
Site 49
T163
S
T
A
S
L
T
R
T
P
S
R
A
S
L
T
Site 50
S165
A
S
L
T
R
T
P
S
R
A
S
L
T
R
W
Site 51
S168
T
R
T
P
S
R
A
S
L
T
R
W
P
P
R
Site 52
T170
T
P
S
R
A
S
L
T
R
W
P
P
R
A
S
Site 53
S177
T
R
W
P
P
R
A
S
P
T
R
T
P
P
R
Site 54
T181
P
R
A
S
P
T
R
T
P
P
R
E
S
P
R
Site 55
S186
T
R
T
P
P
R
E
S
P
R
M
S
H
R
A
Site 56
S190
P
R
E
S
P
R
M
S
H
R
A
S
P
T
R
Site 57
S194
P
R
M
S
H
R
A
S
P
T
R
T
P
P
R
Site 58
T198
H
R
A
S
P
T
R
T
P
P
R
A
S
P
T
Site 59
S203
T
R
T
P
P
R
A
S
P
T
R
R
P
P
R
Site 60
T205
T
P
P
R
A
S
P
T
R
R
P
P
R
A
S
Site 61
S212
T
R
R
P
P
R
A
S
P
T
R
T
P
P
R
Site 62
T214
R
P
P
R
A
S
P
T
R
T
P
P
R
E
S
Site 63
T216
P
R
A
S
P
T
R
T
P
P
R
E
S
L
R
Site 64
S221
T
R
T
P
P
R
E
S
L
R
T
S
H
R
A
Site 65
T224
P
P
R
E
S
L
R
T
S
H
R
A
S
P
T
Site 66
S225
P
R
E
S
L
R
T
S
H
R
A
S
P
T
R
Site 67
S229
L
R
T
S
H
R
A
S
P
T
R
M
P
P
R
Site 68
S238
T
R
M
P
P
R
A
S
P
T
R
R
P
P
R
Site 69
T240
M
P
P
R
A
S
P
T
R
R
P
P
R
A
S
Site 70
S247
T
R
R
P
P
R
A
S
P
T
G
S
P
P
R
Site 71
T249
R
P
P
R
A
S
P
T
G
S
P
P
R
A
S
Site 72
S251
P
R
A
S
P
T
G
S
P
P
R
A
S
P
M
Site 73
S256
T
G
S
P
P
R
A
S
P
M
T
P
P
R
A
Site 74
T259
P
P
R
A
S
P
M
T
P
P
R
A
S
P
R
Site 75
S264
P
M
T
P
P
R
A
S
P
R
T
P
P
R
A
Site 76
T267
P
P
R
A
S
P
R
T
P
P
R
A
S
P
T
Site 77
S272
P
R
T
P
P
R
A
S
P
T
T
T
P
S
R
Site 78
T274
T
P
P
R
A
S
P
T
T
T
P
S
R
A
S
Site 79
T275
P
P
R
A
S
P
T
T
T
P
S
R
A
S
L
Site 80
T276
P
R
A
S
P
T
T
T
P
S
R
A
S
L
T
Site 81
S278
A
S
P
T
T
T
P
S
R
A
S
L
T
R
T
Site 82
S281
T
T
T
P
S
R
A
S
L
T
R
T
P
S
W
Site 83
T283
T
P
S
R
A
S
L
T
R
T
P
S
W
A
S
Site 84
T285
S
R
A
S
L
T
R
T
P
S
W
A
S
P
T
Site 85
S287
A
S
L
T
R
T
P
S
W
A
S
P
T
T
T
Site 86
S290
T
R
T
P
S
W
A
S
P
T
T
T
P
S
R
Site 87
T292
T
P
S
W
A
S
P
T
T
T
P
S
R
A
S
Site 88
T293
P
S
W
A
S
P
T
T
T
P
S
R
A
S
L
Site 89
T294
S
W
A
S
P
T
T
T
P
S
R
A
S
L
M
Site 90
S296
A
S
P
T
T
T
P
S
R
A
S
L
M
K
M
Site 91
S299
T
T
T
P
S
R
A
S
L
M
K
M
E
S
T
Site 92
S305
A
S
L
M
K
M
E
S
T
V
S
I
T
R
T
Site 93
T306
S
L
M
K
M
E
S
T
V
S
I
T
R
T
P
Site 94
S308
M
K
M
E
S
T
V
S
I
T
R
T
P
P
R
Site 95
T312
S
T
V
S
I
T
R
T
P
P
R
A
S
P
T
Site 96
S317
T
R
T
P
P
R
A
S
P
T
G
T
P
S
R
Site 97
T319
T
P
P
R
A
S
P
T
G
T
P
S
R
A
S
Site 98
T321
P
R
A
S
P
T
G
T
P
S
R
A
S
P
T
Site 99
S323
A
S
P
T
G
T
P
S
R
A
S
P
T
G
T
Site 100
S326
T
G
T
P
S
R
A
S
P
T
G
T
P
S
R
Site 101
T328
T
P
S
R
A
S
P
T
G
T
P
S
R
A
S
Site 102
T330
S
R
A
S
P
T
G
T
P
S
R
A
S
L
T
Site 103
S332
A
S
P
T
G
T
P
S
R
A
S
L
T
G
S
Site 104
S335
T
G
T
P
S
R
A
S
L
T
G
S
P
S
R
Site 105
T337
T
P
S
R
A
S
L
T
G
S
P
S
R
A
S
Site 106
S339
S
R
A
S
L
T
G
S
P
S
R
A
S
L
T
Site 107
S341
A
S
L
T
G
S
P
S
R
A
S
L
T
G
T
Site 108
S344
T
G
S
P
S
R
A
S
L
T
G
T
P
S
R
Site 109
T346
S
P
S
R
A
S
L
T
G
T
P
S
R
A
S
Site 110
T348
S
R
A
S
L
T
G
T
P
S
R
A
S
L
I
Site 111
S353
T
G
T
P
S
R
A
S
L
I
G
T
P
S
R
Site 112
S362
I
G
T
P
S
R
A
S
L
I
G
T
P
S
R
Site 113
T366
S
R
A
S
L
I
G
T
P
S
R
A
S
L
T
Site 114
S371
I
G
T
P
S
R
A
S
L
T
G
T
P
P
R
Site 115
T373
T
P
S
R
A
S
L
T
G
T
P
P
R
A
S
Site 116
T375
S
R
A
S
L
T
G
T
P
P
R
A
S
L
T
Site 117
S380
T
G
T
P
P
R
A
S
L
T
G
T
S
S
T
Site 118
T382
T
P
P
R
A
S
L
T
G
T
S
S
T
A
S
Site 119
T384
P
R
A
S
L
T
G
T
S
S
T
A
S
L
T
Site 120
S385
R
A
S
L
T
G
T
S
S
T
A
S
L
T
R
Site 121
S386
A
S
L
T
G
T
S
S
T
A
S
L
T
R
T
Site 122
T387
S
L
T
G
T
S
S
T
A
S
L
T
R
T
P
Site 123
S389
T
G
T
S
S
T
A
S
L
T
R
T
P
S
R
Site 124
T391
T
S
S
T
A
S
L
T
R
T
P
S
R
A
S
Site 125
S395
A
S
L
T
R
T
P
S
R
A
S
L
T
R
T
Site 126
S398
T
R
T
P
S
R
A
S
L
T
R
T
Q
S
S
Site 127
T400
T
P
S
R
A
S
L
T
R
T
Q
S
S
S
S
Site 128
T402
S
R
A
S
L
T
R
T
Q
S
S
S
S
L
T
Site 129
S404
A
S
L
T
R
T
Q
S
S
S
S
L
T
R
T
Site 130
S406
L
T
R
T
Q
S
S
S
S
L
T
R
T
P
S
Site 131
S407
T
R
T
Q
S
S
S
S
L
T
R
T
P
S
M
Site 132
T409
T
Q
S
S
S
S
L
T
R
T
P
S
M
A
S
Site 133
T411
S
S
S
S
L
T
R
T
P
S
M
A
S
L
T
Site 134
S413
S
S
L
T
R
T
P
S
M
A
S
L
T
R
T
Site 135
S416
T
R
T
P
S
M
A
S
L
T
R
T
P
P
R
Site 136
T418
T
P
S
M
A
S
L
T
R
T
P
P
R
A
S
Site 137
T420
S
M
A
S
L
T
R
T
P
P
R
A
S
L
T
Site 138
S425
T
R
T
P
P
R
A
S
L
T
R
T
P
P
R
Site 139
T427
T
P
P
R
A
S
L
T
R
T
P
P
R
A
S
Site 140
T429
P
R
A
S
L
T
R
T
P
P
R
A
S
L
T
Site 141
S452
T
R
T
P
P
R
A
S
L
T
R
T
P
S
M
Site 142
T454
T
P
P
R
A
S
L
T
R
T
P
S
M
V
S
Site 143
T456
P
R
A
S
L
T
R
T
P
S
M
V
S
L
K
Site 144
S458
A
S
L
T
R
T
P
S
M
V
S
L
K
R
S
Site 145
S461
T
R
T
P
S
M
V
S
L
K
R
S
P
S
R
Site 146
S465
S
M
V
S
L
K
R
S
P
S
R
A
S
L
T
Site 147
S467
V
S
L
K
R
S
P
S
R
A
S
L
T
R
T
Site 148
S470
K
R
S
P
S
R
A
S
L
T
R
T
P
S
R
Site 149
T472
S
P
S
R
A
S
L
T
R
T
P
S
R
A
S
Site 150
T474
S
R
A
S
L
T
R
T
P
S
R
A
S
L
T
Site 151
S476
A
S
L
T
R
T
P
S
R
A
S
L
T
M
T
Site 152
S479
T
R
T
P
S
R
A
S
L
T
M
T
P
S
R
Site 153
T481
T
P
S
R
A
S
L
T
M
T
P
S
R
A
S
Site 154
T483
S
R
A
S
L
T
M
T
P
S
R
A
S
L
T
Site 155
S485
A
S
L
T
M
T
P
S
R
A
S
L
T
R
T
Site 156
S488
T
M
T
P
S
R
A
S
L
T
R
T
P
S
T
Site 157
T490
T
P
S
R
A
S
L
T
R
T
P
S
T
A
S
Site 158
T492
S
R
A
S
L
T
R
T
P
S
T
A
S
L
T
Site 159
S494
A
S
L
T
R
T
P
S
T
A
S
L
T
G
T
Site 160
T495
S
L
T
R
T
P
S
T
A
S
L
T
G
T
P
Site 161
S497
T
R
T
P
S
T
A
S
L
T
G
T
P
P
T
Site 162
T499
T
P
S
T
A
S
L
T
G
T
P
P
T
A
S
Site 163
T501
S
T
A
S
L
T
G
T
P
P
T
A
S
L
T
Site 164
S506
T
G
T
P
P
T
A
S
L
T
R
T
P
P
T
Site 165
T508
T
P
P
T
A
S
L
T
R
T
P
P
T
A
S
Site 166
T510
P
T
A
S
L
T
R
T
P
P
T
A
S
L
T
Site 167
T513
S
L
T
R
T
P
P
T
A
S
L
T
R
S
P
Site 168
S515
T
R
T
P
P
T
A
S
L
T
R
S
P
P
T
Site 169
T517
T
P
P
T
A
S
L
T
R
S
P
P
T
A
S
Site 170
S519
P
T
A
S
L
T
R
S
P
P
T
A
S
L
T
Site 171
S524
T
R
S
P
P
T
A
S
L
T
R
T
P
S
T
Site 172
T526
S
P
P
T
A
S
L
T
R
T
P
S
T
A
S
Site 173
T528
P
T
A
S
L
T
R
T
P
S
T
A
S
L
T
Site 174
S530
A
S
L
T
R
T
P
S
T
A
S
L
T
R
M
Site 175
T531
S
L
T
R
T
P
S
T
A
S
L
T
R
M
P
Site 176
S533
T
R
T
P
S
T
A
S
L
T
R
M
P
S
T
Site 177
T535
T
P
S
T
A
S
L
T
R
M
P
S
T
A
S
Site 178
S539
A
S
L
T
R
M
P
S
T
A
S
L
T
R
K
Site 179
T540
S
L
T
R
M
P
S
T
A
S
L
T
R
K
S
Site 180
S542
T
R
M
P
S
T
A
S
L
T
R
K
S
N
V
Site 181
S547
T
A
S
L
T
R
K
S
N
V
N
Q
Q
C
P
Site 182
S556
V
N
Q
Q
C
P
A
S
T
P
S
S
E
V
I
Site 183
T557
N
Q
Q
C
P
A
S
T
P
S
S
E
V
I
S
Site 184
S559
Q
C
P
A
S
T
P
S
S
E
V
I
S
_
_
Site 185
S560
C
P
A
S
T
P
S
S
E
V
I
S
_
_
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation