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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
DNAH17
Full Name:
Dynein heavy chain 17, axonemal
Alias:
Axonemal beta dynein heavy chain 17; DNAHL1; DNEL2; dynein, axonemal, heavy chain 17; FLJ40457
Type:
Mass (Da):
511787
Number AA:
4485
UniProt ID:
Q9UFH2
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005858
GO:0035085
GO:0005874
Uniprot
OncoNet
Molecular Function:
GO:0005524
GO:0016887
GO:0003777
PhosphoSite+
KinaseNET
Biological Process:
GO:0001539
GO:0007018
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S71
P
C
L
G
F
P
Q
S
L
K
S
K
G
V
Y
Site 2
S74
G
F
P
Q
S
L
K
S
K
G
V
Y
F
I
K
Site 3
Y78
S
L
K
S
K
G
V
Y
F
I
K
T
K
S
E
Site 4
T82
K
G
V
Y
F
I
K
T
K
S
E
N
I
N
K
Site 5
Y92
E
N
I
N
K
D
N
Y
R
A
R
L
L
Y
G
Site 6
Y98
N
Y
R
A
R
L
L
Y
G
D
I
S
P
T
P
Site 7
S102
R
L
L
Y
G
D
I
S
P
T
P
V
D
Q
L
Site 8
S119
V
V
E
E
V
L
S
S
L
L
N
Q
S
E
N
Site 9
S124
L
S
S
L
L
N
Q
S
E
N
M
A
G
W
P
Site 10
S153
K
N
E
M
F
V
M
S
G
K
I
K
G
K
T
Site 11
T160
S
G
K
I
K
G
K
T
L
L
P
I
P
E
H
Site 12
S170
P
I
P
E
H
L
G
S
L
D
G
T
L
E
S
Site 13
T174
H
L
G
S
L
D
G
T
L
E
S
M
E
R
I
Site 14
S177
S
L
D
G
T
L
E
S
M
E
R
I
P
S
S
Site 15
S183
E
S
M
E
R
I
P
S
S
L
D
N
L
L
L
Site 16
S184
S
M
E
R
I
P
S
S
L
D
N
L
L
L
H
Site 17
S209
H
Q
I
R
D
V
L
S
K
D
S
A
Q
A
L
Site 18
S212
R
D
V
L
S
K
D
S
A
Q
A
L
L
D
G
Site 19
S262
E
I
L
E
K
A
K
S
C
Y
W
P
A
L
Q
Site 20
Y272
W
P
A
L
Q
N
V
Y
T
N
V
T
E
G
L
Site 21
T273
P
A
L
Q
N
V
Y
T
N
V
T
E
G
L
K
Site 22
Y328
I
W
A
T
S
E
Y
Y
N
T
P
A
R
I
I
Site 23
T351
Q
I
I
E
M
T
R
T
F
L
S
P
E
E
V
Site 24
S354
E
M
T
R
T
F
L
S
P
E
E
V
L
K
G
Site 25
S411
V
P
W
E
F
P
S
S
L
A
F
S
R
I
N
Site 26
S419
L
A
F
S
R
I
N
S
F
F
Q
R
I
Q
T
Site 27
T426
S
F
F
Q
R
I
Q
T
I
E
E
L
Y
K
T
Site 28
Y476
K
V
F
A
D
C
K
Y
D
P
L
D
P
G
D
Site 29
S484
D
P
L
D
P
G
D
S
N
F
D
R
D
Y
A
Site 30
Y490
D
S
N
F
D
R
D
Y
A
D
F
E
I
K
I
Site 31
T506
D
L
D
R
R
L
A
T
I
F
C
Q
G
F
D
Site 32
Y563
L
D
N
A
K
I
L
Y
D
A
Q
M
A
A
S
Site 33
S592
V
A
G
Q
L
K
W
S
L
E
L
Q
E
R
L
Site 34
S602
L
Q
E
R
L
E
V
S
M
K
H
L
K
H
V
Site 35
T622
S
G
A
E
A
K
L
T
Y
Q
K
Y
D
E
M
Site 36
Y626
A
K
L
T
Y
Q
K
Y
D
E
M
M
E
L
L
Site 37
Y641
R
C
H
R
E
K
I
Y
Q
Q
W
V
A
G
V
Site 38
Y687
A
V
L
R
E
V
K
Y
L
N
F
Q
Q
Q
K
Site 39
S699
Q
Q
K
E
I
P
D
S
A
E
S
L
F
S
E
Site 40
S702
E
I
P
D
S
A
E
S
L
F
S
E
N
E
T
Site 41
S705
D
S
A
E
S
L
F
S
E
N
E
T
F
R
K
Site 42
T709
S
L
F
S
E
N
E
T
F
R
K
F
V
G
N
Site 43
T729
G
W
Y
N
E
I
K
T
I
V
K
A
V
E
F
Site 44
T756
K
L
L
S
A
E
T
T
L
F
W
N
G
E
G
Site 45
Y767
N
G
E
G
V
F
Q
Y
I
Q
E
V
R
E
I
Site 46
S800
S
Q
A
M
K
D
W
S
A
N
P
L
F
E
R
Site 47
T854
A
E
L
F
R
A
D
T
L
S
L
P
W
K
D
Site 48
S856
L
F
R
A
D
T
L
S
L
P
W
K
D
Y
V
Site 49
Y865
P
W
K
D
Y
V
I
Y
I
D
D
M
V
L
D
Site 50
S881
F
D
Q
F
I
R
K
S
L
S
F
L
M
D
N
Site 51
T911
E
L
D
E
D
G
L
T
F
N
P
T
L
E
V
Site 52
T915
D
G
L
T
F
N
P
T
L
E
V
G
S
D
R
Site 53
S920
N
P
T
L
E
V
G
S
D
R
G
F
L
A
L
Site 54
Y952
L
A
K
D
R
M
N
Y
K
M
D
L
E
D
N
Site 55
T960
K
M
D
L
E
D
N
T
D
L
I
E
M
R
E
Site 56
S971
E
M
R
E
E
V
S
S
L
V
I
N
A
M
K
Site 57
Y983
A
M
K
E
A
E
E
Y
Q
D
S
F
E
R
Y
Site 58
S986
E
A
E
E
Y
Q
D
S
F
E
R
Y
S
Y
L
Site 59
Y990
Y
Q
D
S
F
E
R
Y
S
Y
L
W
T
D
N
Site 60
Y992
D
S
F
E
R
Y
S
Y
L
W
T
D
N
L
Q
Site 61
T1019
V
T
A
E
D
L
D
T
W
T
D
D
T
I
P
Site 62
T1021
A
E
D
L
D
T
W
T
D
D
T
I
P
K
T
Site 63
T1024
L
D
T
W
T
D
D
T
I
P
K
T
P
P
T
Site 64
T1028
T
D
D
T
I
P
K
T
P
P
T
L
A
Q
F
Site 65
T1031
T
I
P
K
T
P
P
T
L
A
Q
F
Q
E
Q
Site 66
S1041
Q
F
Q
E
Q
I
D
S
Y
E
K
L
Y
E
E
Site 67
Y1042
F
Q
E
Q
I
D
S
Y
E
K
L
Y
E
E
V
Site 68
Y1046
I
D
S
Y
E
K
L
Y
E
E
V
S
K
C
E
Site 69
S1050
E
K
L
Y
E
E
V
S
K
C
E
N
T
K
V
Site 70
S1075
P
F
K
Q
A
L
L
S
T
I
R
R
W
G
F
Site 71
T1093
R
H
L
S
N
H
V
T
N
S
L
A
D
L
E
Site 72
Y1119
K
P
L
K
E
G
D
Y
D
G
L
V
E
V
M
Site 73
T1155
Q
T
I
E
L
L
K
T
Y
G
E
E
M
P
E
Site 74
S1198
P
L
Q
A
N
E
V
S
I
L
R
R
K
C
Q
Site 75
S1225
F
R
R
E
A
P
F
S
F
S
D
P
N
P
Y
Site 76
S1227
R
E
A
P
F
S
F
S
D
P
N
P
Y
K
S
Site 77
S1234
S
D
P
N
P
Y
K
S
L
N
K
V
F
L
L
Site 78
S1249
K
G
I
M
E
A
L
S
K
S
G
G
L
F
E
Site 79
Y1262
F
E
V
P
V
P
D
Y
K
Q
L
K
A
C
H
Site 80
S1318
K
F
A
K
D
M
R
S
L
D
K
E
M
K
T
Site 81
T1325
S
L
D
K
E
M
K
T
W
D
A
F
V
G
L
Site 82
Y1389
L
Q
L
N
L
H
S
Y
E
D
E
V
R
N
I
Site 83
S1415
K
V
L
K
A
L
D
S
T
W
S
M
M
E
F
Site 84
T1432
E
P
H
P
R
T
G
T
M
M
L
K
S
S
E
Site 85
Y1460
Q
N
L
M
M
S
K
Y
L
A
H
F
L
K
E
Site 86
S1470
H
F
L
K
E
V
T
S
W
Q
Q
K
L
S
T
Site 87
S1476
T
S
W
Q
Q
K
L
S
T
A
D
S
V
I
S
Site 88
T1477
S
W
Q
Q
K
L
S
T
A
D
S
V
I
S
I
Site 89
S1497
R
T
W
S
H
L
E
S
I
F
I
G
S
E
D
Site 90
T1507
I
G
S
E
D
I
R
T
Q
L
P
G
D
S
Q
Site 91
S1513
R
T
Q
L
P
G
D
S
Q
R
F
D
D
I
N
Site 92
S1555
K
L
E
A
L
K
K
S
L
A
I
C
E
K
A
Site 93
T1569
A
L
A
E
Y
L
E
T
K
R
L
A
F
P
R
Site 94
Y1578
R
L
A
F
P
R
F
Y
F
V
S
S
A
D
L
Site 95
S1581
F
P
R
F
Y
F
V
S
S
A
D
L
L
D
I
Site 96
S1590
A
D
L
L
D
I
L
S
N
G
N
D
P
V
E
Site 97
S1599
G
N
D
P
V
E
V
S
R
H
L
S
K
L
F
Site 98
S1608
H
L
S
K
L
F
D
S
L
C
K
L
K
F
R
Site 99
S1619
L
K
F
R
L
D
A
S
D
K
P
L
K
V
G
Site 100
Y1636
M
Y
S
K
E
D
E
Y
M
V
F
D
Q
E
C
Site 101
S1662
R
V
L
D
R
M
C
S
T
L
R
H
E
I
P
Site 102
T1663
V
L
D
R
M
C
S
T
L
R
H
E
I
P
E
Site 103
T1674
E
I
P
E
A
V
V
T
Y
E
E
K
P
R
E
Site 104
Y1708
F
A
R
L
E
E
G
Y
E
N
A
I
K
D
Y
Site 105
Y1715
Y
E
N
A
I
K
D
Y
N
K
K
Q
I
S
Q
Site 106
S1721
D
Y
N
K
K
Q
I
S
Q
L
N
V
L
I
T
Site 107
S1764
A
K
M
I
V
E
S
S
Q
A
F
T
W
Q
A
Site 108
T1768
V
E
S
S
Q
A
F
T
W
Q
A
Q
L
R
H
Site 109
Y1799
Q
I
Q
Y
S
Y
E
Y
L
G
N
T
P
R
L
Site 110
T1803
S
Y
E
Y
L
G
N
T
P
R
L
V
I
T
P
Site 111
T1809
N
T
P
R
L
V
I
T
P
L
T
D
R
C
Y
Site 112
Y1816
T
P
L
T
D
R
C
Y
I
T
L
T
Q
S
L
Site 113
T1840
G
P
A
G
T
G
K
T
E
T
T
K
D
L
G
Site 114
Y1865
N
C
S
E
Q
M
D
Y
K
S
C
G
N
I
Y
Site 115
Y1939
F
I
T
M
N
P
G
Y
A
G
R
A
E
L
P
Site 116
Y2003
L
L
S
K
Q
D
H
Y
D
W
G
L
R
A
I
Site 117
S2109
E
L
L
Q
V
R
H
S
V
F
I
V
G
N
A
Site 118
S2121
G
N
A
G
S
G
K
S
Q
V
L
K
S
L
N
Site 119
S2126
G
K
S
Q
V
L
K
S
L
N
K
T
Y
Q
N
Site 120
T2130
V
L
K
S
L
N
K
T
Y
Q
N
L
K
R
K
Site 121
T2161
F
G
I
I
N
P
V
T
R
E
W
K
D
G
L
Site 122
T2171
W
K
D
G
L
F
S
T
I
M
R
D
L
A
N
Site 123
T2212
M
D
D
N
K
V
L
T
L
A
S
N
E
R
I
Site 124
S2215
N
K
V
L
T
L
A
S
N
E
R
I
P
L
N
Site 125
T2238
I
S
H
L
R
T
A
T
P
A
T
V
S
R
A
Site 126
S2272
I
E
R
R
K
V
Q
S
E
K
A
N
L
M
I
Site 127
T2287
L
F
D
K
Y
L
P
T
C
L
D
K
L
R
F
Site 128
T2323
E
C
L
L
T
E
K
T
V
P
P
D
S
P
R
Site 129
S2328
E
K
T
V
P
P
D
S
P
R
E
L
Y
E
L
Site 130
Y2333
P
D
S
P
R
E
L
Y
E
L
Y
F
V
F
T
Site 131
Y2357
F
Q
D
Q
L
V
D
Y
R
V
E
F
S
K
W
Site 132
Y2383
S
Q
G
T
I
F
D
Y
Y
I
D
P
D
T
K
Site 133
Y2384
Q
G
T
I
F
D
Y
Y
I
D
P
D
T
K
K
Site 134
T2396
T
K
K
F
L
P
W
T
D
K
V
P
S
F
E
Site 135
S2401
P
W
T
D
K
V
P
S
F
E
L
D
P
D
V
Site 136
S2413
P
D
V
P
L
Q
A
S
L
V
H
T
T
E
T
Site 137
T2417
L
Q
A
S
L
V
H
T
T
E
T
I
R
I
R
Site 138
S2448
G
N
A
G
T
G
K
S
V
L
M
G
D
K
L
Site 139
S2457
L
M
G
D
K
L
E
S
L
N
T
D
N
Y
L
Site 140
T2460
D
K
L
E
S
L
N
T
D
N
Y
L
V
Q
A
Site 141
Y2463
E
S
L
N
T
D
N
Y
L
V
Q
A
V
P
F
Site 142
S2491
E
K
P
L
E
K
K
S
G
R
N
Y
G
P
P
Site 143
Y2495
E
K
K
S
G
R
N
Y
G
P
P
G
T
K
K
Site 144
Y2505
P
G
T
K
K
L
V
Y
F
I
D
D
M
N
M
Site 145
Y2518
N
M
P
E
V
D
K
Y
G
T
V
A
P
H
T
Site 146
T2520
P
E
V
D
K
Y
G
T
V
A
P
H
T
L
I
Site 147
T2525
Y
G
T
V
A
P
H
T
L
I
R
Q
H
M
D
Site 148
S2562
C
M
N
P
T
S
G
S
F
T
I
D
S
R
L
Site 149
T2564
N
P
T
S
G
S
F
T
I
D
S
R
L
Q
R
Site 150
S2567
S
G
S
F
T
I
D
S
R
L
Q
R
H
F
C
Site 151
S2602
T
Q
H
L
A
F
R
S
V
S
M
A
I
Q
R
Site 152
T2674
V
R
L
W
L
H
E
T
E
R
V
Y
G
D
K
Site 153
Y2678
L
H
E
T
E
R
V
Y
G
D
K
M
V
D
E
Site 154
T2690
V
D
E
K
D
Q
E
T
L
H
R
V
T
M
A
Site 155
T2695
Q
E
T
L
H
R
V
T
M
A
S
T
K
K
F
Site 156
S2698
L
H
R
V
T
M
A
S
T
K
K
F
F
D
D
Site 157
Y2730
Q
G
I
G
D
P
K
Y
V
P
V
T
D
M
A
Site 158
T2734
D
P
K
Y
V
P
V
T
D
M
A
P
L
N
K
Site 159
S2778
R
I
N
R
I
L
E
S
P
R
G
N
A
L
L
Site 160
S2795
V
G
G
S
G
K
Q
S
L
S
R
L
A
A
Y
Site 161
S2797
G
S
G
K
Q
S
L
S
R
L
A
A
Y
I
S
Site 162
Y2817
Q
I
T
L
K
K
G
Y
G
I
P
D
L
K
I
Site 163
S2847
S
V
F
L
M
T
D
S
Q
V
A
E
E
Q
F
Site 164
S2881
D
E
V
E
N
I
I
S
S
M
R
P
Q
V
K
Site 165
S2882
E
V
E
N
I
I
S
S
M
R
P
Q
V
K
S
Site 166
S2889
S
M
R
P
Q
V
K
S
L
G
M
N
D
T
R
Site 167
S2955
E
D
A
L
V
S
V
S
A
R
F
L
E
E
T
Site 168
T2962
S
A
R
F
L
E
E
T
E
G
I
P
W
E
V
Site 169
T2982
F
F
M
S
Y
V
H
T
T
V
N
E
M
S
R
Site 170
Y2991
V
N
E
M
S
R
V
Y
L
A
T
E
R
R
Y
Site 171
T2994
M
S
R
V
Y
L
A
T
E
R
R
Y
N
Y
T
Site 172
Y2998
Y
L
A
T
E
R
R
Y
N
Y
T
T
P
K
T
Site 173
Y3000
A
T
E
R
R
Y
N
Y
T
T
P
K
T
F
L
Site 174
T3001
T
E
R
R
Y
N
Y
T
T
P
K
T
F
L
E
Site 175
T3002
E
R
R
Y
N
Y
T
T
P
K
T
F
L
E
Q
Site 176
T3005
Y
N
Y
T
T
P
K
T
F
L
E
Q
I
K
L
Site 177
Y3013
F
L
E
Q
I
K
L
Y
Q
N
L
L
A
K
K
Site 178
S3040
N
G
L
M
K
L
Q
S
T
A
S
Q
V
D
D
Site 179
S3043
M
K
L
Q
S
T
A
S
Q
V
D
D
L
K
A
Site 180
T3128
A
A
Q
E
A
L
D
T
L
N
K
N
N
L
T
Site 181
T3135
T
L
N
K
N
N
L
T
E
L
K
S
F
G
S
Site 182
S3139
N
N
L
T
E
L
K
S
F
G
S
P
P
D
A
Site 183
S3142
T
E
L
K
S
F
G
S
P
P
D
A
V
V
N
Site 184
S3169
G
K
I
P
K
D
K
S
W
K
A
A
K
I
M
Site 185
S3186
K
V
D
T
F
L
D
S
L
K
K
F
D
K
E
Site 186
T3211
K
P
Y
Q
G
N
P
T
F
D
P
E
F
I
R
Site 187
S3219
F
D
P
E
F
I
R
S
K
S
T
A
A
A
G
Site 188
Y3241
I
V
R
F
Y
E
V
Y
C
D
V
A
P
K
R
Site 189
S3280
A
E
L
N
A
N
L
S
N
L
T
S
A
F
E
Site 190
S3284
A
N
L
S
N
L
T
S
A
F
E
K
A
T
A
Site 191
S3319
R
L
V
G
G
L
A
S
E
N
I
R
W
A
E
Site 192
S3327
E
N
I
R
W
A
E
S
V
E
N
F
R
S
Q
Site 193
S3333
E
S
V
E
N
F
R
S
Q
G
V
T
L
C
G
Site 194
Y3354
A
F
V
S
Y
V
G
Y
F
T
K
K
Y
R
N
Site 195
Y3359
V
G
Y
F
T
K
K
Y
R
N
E
L
M
E
K
Site 196
S3389
T
N
G
L
D
P
L
S
L
L
T
D
D
A
D
Site 197
T3399
T
D
D
A
D
V
A
T
W
N
N
Q
G
L
P
Site 198
S3407
W
N
N
Q
G
L
P
S
D
R
M
S
T
E
N
Site 199
S3411
G
L
P
S
D
R
M
S
T
E
N
A
T
I
L
Site 200
T3412
L
P
S
D
R
M
S
T
E
N
A
T
I
L
G
Site 201
S3455
A
I
R
L
G
Q
K
S
Y
L
D
V
I
E
Q
Site 202
Y3456
I
R
L
G
Q
K
S
Y
L
D
V
I
E
Q
A
Site 203
T3491
D
P
L
L
G
R
N
T
I
K
K
G
K
Y
I
Site 204
Y3497
N
T
I
K
K
G
K
Y
I
K
I
G
D
K
E
Site 205
Y3507
I
G
D
K
E
V
E
Y
H
P
K
F
R
L
I
Site 206
Y3519
R
L
I
L
H
T
K
Y
F
N
P
H
Y
K
P
Site 207
Y3524
T
K
Y
F
N
P
H
Y
K
P
E
M
Q
A
Q
Site 208
T3568
E
Q
L
K
A
N
L
T
K
S
Q
N
E
F
K
Site 209
S3570
L
K
A
N
L
T
K
S
Q
N
E
F
K
I
V
Site 210
S3590
D
S
L
L
A
R
L
S
A
A
S
G
N
F
L
Site 211
T3600
S
G
N
F
L
G
D
T
A
L
V
E
N
L
E
Site 212
T3608
A
L
V
E
N
L
E
T
T
K
H
T
A
S
E
Site 213
T3612
N
L
E
T
T
K
H
T
A
S
E
I
E
E
K
Site 214
S3614
E
T
T
K
H
T
A
S
E
I
E
E
K
V
V
Site 215
T3626
K
V
V
E
A
K
I
T
E
V
K
I
N
E
A
Site 216
Y3637
I
N
E
A
R
E
N
Y
R
P
A
A
E
R
A
Site 217
T3680
E
K
A
I
Q
R
T
T
P
A
N
E
V
K
Q
Site 218
T3693
K
Q
R
V
I
N
L
T
D
E
I
T
Y
S
V
Site 219
Y3701
D
E
I
T
Y
S
V
Y
M
Y
T
A
R
G
L
Site 220
S3726
Q
V
T
F
Q
V
L
S
M
K
K
E
L
N
P
Site 221
S3767
W
G
G
I
K
A
L
S
E
M
D
E
F
K
N
Site 222
S3777
D
E
F
K
N
L
D
S
D
I
E
G
S
A
K
Site 223
S3782
L
D
S
D
I
E
G
S
A
K
R
W
K
K
L
Site 224
S3792
R
W
K
K
L
V
E
S
E
A
P
E
K
E
I
Site 225
Y3826
L
R
P
D
R
M
T
Y
A
I
K
N
F
V
E
Site 226
S3838
F
V
E
E
K
M
G
S
K
F
V
E
G
R
S
Site 227
S3845
S
K
F
V
E
G
R
S
V
E
F
S
K
S
Y
Site 228
S3849
E
G
R
S
V
E
F
S
K
S
Y
E
E
S
S
Site 229
S3851
R
S
V
E
F
S
K
S
Y
E
E
S
S
P
S
Site 230
Y3852
S
V
E
F
S
K
S
Y
E
E
S
S
P
S
T
Site 231
S3855
F
S
K
S
Y
E
E
S
S
P
S
T
S
I
F
Site 232
S3856
S
K
S
Y
E
E
S
S
P
S
T
S
I
F
F
Site 233
S3858
S
Y
E
E
S
S
P
S
T
S
I
F
F
I
L
Site 234
T3859
Y
E
E
S
S
P
S
T
S
I
F
F
I
L
S
Site 235
S3860
E
E
S
S
P
S
T
S
I
F
F
I
L
S
P
Site 236
S3895
N
G
K
L
H
N
V
S
L
G
Q
G
Q
E
V
Site 237
T3940
L
V
A
R
W
L
G
T
L
D
K
K
L
E
R
Site 238
Y3948
L
D
K
K
L
E
R
Y
S
T
G
S
H
E
D
Site 239
S3949
D
K
K
L
E
R
Y
S
T
G
S
H
E
D
Y
Site 240
T3950
K
K
L
E
R
Y
S
T
G
S
H
E
D
Y
R
Site 241
S3952
L
E
R
Y
S
T
G
S
H
E
D
Y
R
V
F
Site 242
Y3956
S
T
G
S
H
E
D
Y
R
V
F
I
S
A
E
Site 243
S3961
E
D
Y
R
V
F
I
S
A
E
P
A
P
S
P
Site 244
S3967
I
S
A
E
P
A
P
S
P
E
T
H
I
I
P
Site 245
T3970
E
P
A
P
S
P
E
T
H
I
I
P
Q
G
I
Site 246
T3985
L
E
N
A
I
K
I
T
N
E
P
P
T
G
M
Site 247
T4007
L
D
L
F
T
Q
D
T
L
E
M
C
T
K
E
Site 248
Y4046
A
Q
G
W
N
R
S
Y
P
F
N
N
G
D
L
Site 249
Y4063
S
I
N
V
L
Y
N
Y
L
E
A
N
P
K
V
Site 250
Y4077
V
P
W
D
D
L
R
Y
L
F
G
E
I
M
Y
Site 251
T4099
W
D
R
R
L
C
R
T
Y
L
A
E
Y
I
R
Site 252
Y4100
D
R
R
L
C
R
T
Y
L
A
E
Y
I
R
T
Site 253
Y4104
C
R
T
Y
L
A
E
Y
I
R
T
E
M
L
E
Site 254
T4107
Y
L
A
E
Y
I
R
T
E
M
L
E
G
D
V
Site 255
Y4128
Q
I
P
P
N
L
D
Y
K
G
Y
H
E
Y
I
Site 256
Y4131
P
N
L
D
Y
K
G
Y
H
E
Y
I
D
E
N
Site 257
S4143
D
E
N
L
P
P
E
S
P
Y
L
Y
G
L
H
Site 258
Y4145
N
L
P
P
E
S
P
Y
L
Y
G
L
H
P
N
Site 259
Y4147
P
P
E
S
P
Y
L
Y
G
L
H
P
N
A
E
Site 260
T4168
T
S
E
K
L
F
R
T
V
L
E
M
Q
P
K
Site 261
S4179
M
Q
P
K
E
T
D
S
G
A
G
T
G
V
S
Site 262
T4183
E
T
D
S
G
A
G
T
G
V
S
R
E
E
K
Site 263
S4186
S
G
A
G
T
G
V
S
R
E
E
K
A
G
S
Site 264
S4193
S
R
E
E
K
A
G
S
L
K
L
L
P
S
E
Site 265
S4199
G
S
L
K
L
L
P
S
E
R
K
G
E
D
L
Site 266
Y4250
K
A
A
E
K
T
P
Y
V
V
V
A
F
Q
E
Site 267
T4265
C
E
R
M
N
I
L
T
N
E
M
R
R
S
L
Site 268
S4271
L
T
N
E
M
R
R
S
L
K
E
L
N
L
G
Site 269
T4284
L
G
L
K
G
E
L
T
I
T
T
D
V
E
D
Site 270
T4286
L
K
G
E
L
T
I
T
T
D
V
E
D
L
S
Site 271
S4293
T
T
D
V
E
D
L
S
T
A
L
F
Y
D
T
Site 272
T4335
R
E
L
E
A
W
T
T
D
F
A
L
P
T
T
Site 273
S4376
P
L
D
K
M
C
L
S
V
E
V
T
K
K
N
Site 274
T4380
M
C
L
S
V
E
V
T
K
K
N
R
E
D
M
Site 275
T4388
K
K
N
R
E
D
M
T
A
P
P
R
E
G
S
Site 276
S4395
T
A
P
P
R
E
G
S
Y
V
Y
G
L
F
M
Site 277
Y4396
A
P
P
R
E
G
S
Y
V
Y
G
L
F
M
E
Site 278
T4409
M
E
G
A
R
W
D
T
Q
T
G
V
I
A
E
Site 279
T4411
G
A
R
W
D
T
Q
T
G
V
I
A
E
A
R
Site 280
T4441
I
P
V
D
R
M
E
T
K
N
I
Y
E
C
P
Site 281
Y4445
R
M
E
T
K
N
I
Y
E
C
P
V
Y
K
T
Site 282
Y4450
N
I
Y
E
C
P
V
Y
K
T
R
I
R
G
P
Site 283
T4458
K
T
R
I
R
G
P
T
Y
V
W
T
F
N
L
Site 284
Y4459
T
R
I
R
G
P
T
Y
V
W
T
F
N
L
K
Site 285
T4462
R
G
P
T
Y
V
W
T
F
N
L
K
T
K
E
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation