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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
MTRF1L
Full Name:
Alias:
Mitochondrial translational release factor 1-like;mtRF1a
Type:
Mass (Da):
43600
Number AA:
380
UniProt ID:
Q9UGC7
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S27
G
P
A
R
R
P
L
S
S
G
S
P
P
L
E
Site 2
S28
P
A
R
R
P
L
S
S
G
S
P
P
L
E
E
Site 3
S30
R
R
P
L
S
S
G
S
P
P
L
E
E
L
F
Site 4
T38
P
P
L
E
E
L
F
T
R
G
G
P
L
R
T
Site 5
T45
T
R
G
G
P
L
R
T
F
L
E
R
Q
A
G
Site 6
T81
K
E
R
E
L
R
E
T
E
H
L
L
H
D
E
Site 7
T101
K
L
A
E
N
E
I
T
L
C
Q
K
E
I
T
Site 8
S121
I
I
L
L
L
V
P
S
E
E
T
D
E
N
D
Site 9
Y153
T
S
E
I
F
D
M
Y
Q
Q
Y
A
A
F
K
Site 10
T166
F
K
R
W
H
F
E
T
L
E
Y
F
P
S
E
Site 11
Y169
W
H
F
E
T
L
E
Y
F
P
S
E
L
G
G
Site 12
S172
E
T
L
E
Y
F
P
S
E
L
G
G
L
R
H
Site 13
S181
L
G
G
L
R
H
A
S
A
S
I
G
G
S
E
Site 14
S183
G
L
R
H
A
S
A
S
I
G
G
S
E
A
Y
Site 15
S187
A
S
A
S
I
G
G
S
E
A
Y
R
H
M
K
Site 16
Y190
S
I
G
G
S
E
A
Y
R
H
M
K
F
E
G
Site 17
T208
R
V
Q
R
V
P
K
T
E
K
Q
G
R
V
H
Site 18
T216
E
K
Q
G
R
V
H
T
S
T
M
T
V
A
I
Site 19
T218
Q
G
R
V
H
T
S
T
M
T
V
A
I
L
P
Site 20
T228
V
A
I
L
P
Q
P
T
E
I
N
L
V
I
N
Site 21
T243
P
K
D
L
R
I
D
T
K
R
A
S
G
A
G
Site 22
S247
R
I
D
T
K
R
A
S
G
A
G
G
Q
H
V
Site 23
S259
Q
H
V
N
T
T
D
S
A
V
R
I
V
H
L
Site 24
S279
S
E
C
Q
Q
E
R
S
Q
L
K
N
K
E
L
Site 25
T289
K
N
K
E
L
A
M
T
K
L
R
A
K
L
Y
Site 26
Y296
T
K
L
R
A
K
L
Y
S
M
H
L
E
E
E
Site 27
S297
K
L
R
A
K
L
Y
S
M
H
L
E
E
E
I
Site 28
S317
A
R
K
I
Q
I
G
S
K
G
R
S
E
K
I
Site 29
S321
Q
I
G
S
K
G
R
S
E
K
I
R
T
Y
N
Site 30
T326
G
R
S
E
K
I
R
T
Y
N
F
P
Q
N
R
Site 31
Y327
R
S
E
K
I
R
T
Y
N
F
P
Q
N
R
V
Site 32
T335
N
F
P
Q
N
R
V
T
D
H
R
I
N
K
T
Site 33
T342
T
D
H
R
I
N
K
T
L
H
D
L
E
T
F
Site 34
T348
K
T
L
H
D
L
E
T
F
M
Q
G
D
Y
L
Site 35
Y354
E
T
F
M
Q
G
D
Y
L
L
D
E
L
V
Q
Site 36
S362
L
L
D
E
L
V
Q
S
L
K
E
Y
A
D
Y
Site 37
Y366
L
V
Q
S
L
K
E
Y
A
D
Y
E
S
L
V
Site 38
Y369
S
L
K
E
Y
A
D
Y
E
S
L
V
E
I
I
Site 39
S371
K
E
Y
A
D
Y
E
S
L
V
E
I
I
S
Q
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation