PhosphoNET

           
Protein Info 
   
Short Name:  PRKAG2
Full Name:  5'-AMP-activated protein kinase subunit gamma-2
Alias:  AAKG2; AMPK gamma2; AMPK gamma-2 chain; H91620p
Type:  AMP-activated protein kinase complex protein; Nucleus
Mass (Da):  63066
Number AA:  569
UniProt ID:  Q9UGJ0
International Prot ID:  IPI00005367
Sequence:  Retrieve full protein sequence
   
GO Terms  External Links Internal Links  
   
Cellular Component:  GO:0031588  GO:0005829  GO:0005654 Uniprot OncoNet
Molecular Function:  GO:0043531  GO:0005524  GO:0004862 PhosphoSite+ KinaseNET
Biological Process:  GO:0006754  GO:0006633  GO:0005977 Phosida TranscriptoNet
    STRING Kinexus Products
   
Info Box  A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites 
-7-6-5-4-3-2-101234567Expt. conf.EffectKinasePPaseKinexus ProductsRef.Evol.Kinase Pred.P-site Match
Site 1S15TKKKKDVSSPGGSGG
Site 2S16KKKKDVSSPGGSGGK
Site 3S20DVSSPGGSGGKKNAS
Site 4S27SGGKKNASQKRRSLR
Site 5S32NASQKRRSLRVHIPD
Site 6S55LDGDLEGSGKHSSRK
Site 7S59LEGSGKHSSRKVDSP
Site 8S60EGSGKHSSRKVDSPF
Site 9S65 HSSRKVDSPFGPGSP
Site 10S71 DSPFGPGSPSKGFFS
Site 11S73 PFGPGSPSKGFFSRG
Site 12S78SPSKGFFSRGPQPRP
Site 13S86 RGPQPRPSSPMSAPV
Site 14S87 GPQPRPSSPMSAPVR
Site 15S90 PRPSSPMSAPVRPKT
Site 16T97SAPVRPKTSPGSPKT
Site 17S98APVRPKTSPGSPKTV
Site 18S101RPKTSPGSPKTVFPF
Site 19T104TSPGSPKTVFPFSYQ
Site 20S109 PKTVFPFSYQESPPR
Site 21Y110KTVFPFSYQESPPRS
Site 22S113 FPFSYQESPPRSPRR
Site 23S117YQESPPRSPRRMSFS
Site 24S122PRSPRRMSFSGIFRS
Site 25S124SPRRMSFSGIFRSSS
Site 26S129SFSGIFRSSSKESSP
Site 27S130 FSGIFRSSSKESSPN
Site 28S131 SGIFRSSSKESSPNS
Site 29S134 FRSSSKESSPNSNPA
Site 30S135 RSSSKESSPNSNPAT
Site 31S138 SKESSPNSNPATSPG
Site 32T142 SPNSNPATSPGGIRF
Site 33S143 PNSNPATSPGGIRFF
Site 34S151 PGGIRFFSRSRKTSG
Site 35S153 GIRFFSRSRKTSGLS
Site 36T156 FFSRSRKTSGLSSSP
Site 37S157 FSRSRKTSGLSSSPS
Site 38S160 SRKTSGLSSSPSTPT
Site 39S161RKTSGLSSSPSTPTQ
Site 40S162 KTSGLSSSPSTPTQV
Site 41S164 SGLSSSPSTPTQVTK
Site 42T165 GLSSSPSTPTQVTKQ
Site 43T167 SSSPSTPTQVTKQHT
Site 44T174TQVTKQHTFPLESYK
Site 45Y180 HTFPLESYKHEPERL
Site 46Y192ERLENRIYASSSPPD
Site 47S195 ENRIYASSSPPDTGQ
Site 48S196 NRIYASSSPPDTGQR
Site 49T200ASSSPPDTGQRFCPS
Site 50S207TGQRFCPSSFQSPTR
Site 51S208GQRFCPSSFQSPTRP
Site 52S211FCPSSFQSPTRPPLA
Site 53T213PSSFQSPTRPPLASP
Site 54S219 PTRPPLASPTHYAPS
Site 55Y223PLASPTHYAPSKAAA
Site 56S256EDEAVEDSESGVYMR
Site 57S258EAVEDSESGVYMRFM
Site 58Y261EDSESGVYMRFMRSH
Site 59Y271FMRSHKCYDIVPTSS
Site 60S309RAAPLWESKKQSFVG
Site 61Y330FINILHRYYKSPMVQ
Site 62Y331INILHRYYKSPMVQI
Site 63S333ILHRYYKSPMVQIYE
Site 64Y353IETWRELYLQETFKP
Site 65T357RELYLQETFKPLVNI
Site 66T486INLAAEKTYNNLDIT
Site 67T493TYNNLDITVTQALQH
Site 68S502TQALQHRSQYFEGVV
Site 69Y504ALQHRSQYFEGVVKC
 
Legend 
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available  
Products available
 


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