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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
WARS2
Full Name:
Tryptophanyl-tRNA synthetase, mitochondrial
Alias:
(Mt)TrpRS; EC 6.1.1.2; SYWM; TrpRS; Tryptophan tRNA ligase 2, mitochondrial; Tryptophan-tRNA ligase; Tryptophan--tRNA ligase; Tryptophanyl tRNA synthetase 2, mitochondrial; Tryptophanyl-tRNA synthetase, mitochondrial
Type:
Amino Acid Metabolism - tryptophan; Ligase; EC 6.1.1.2
Mass (Da):
40147
Number AA:
360
UniProt ID:
Q9UGM6
International Prot ID:
IPI00025050
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005737
GO:0005739
GO:0005759
Uniprot
OncoNet
Molecular Function:
GO:0000166
GO:0003824
GO:0004812
PhosphoSite+
KinaseNET
Biological Process:
GO:0006082
GO:0006139
GO:0006399
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S5
_
_
_
M
A
L
H
S
M
R
K
A
R
E
R
Site 2
S14
R
K
A
R
E
R
W
S
F
I
R
A
L
H
K
Site 3
S23
I
R
A
L
H
K
G
S
A
A
A
P
A
L
Q
Site 4
S33
A
P
A
L
Q
K
D
S
K
K
R
V
F
S
G
Site 5
S39
D
S
K
K
R
V
F
S
G
I
Q
P
T
G
I
Site 6
S58
N
Y
L
G
A
I
E
S
W
V
R
L
Q
D
E
Site 7
Y66
W
V
R
L
Q
D
E
Y
D
S
V
L
Y
S
I
Site 8
S68
R
L
Q
D
E
Y
D
S
V
L
Y
S
I
V
D
Site 9
Y71
D
E
Y
D
S
V
L
Y
S
I
V
D
L
H
S
Site 10
S78
Y
S
I
V
D
L
H
S
I
T
V
P
Q
D
P
Site 11
S91
D
P
A
V
L
R
Q
S
I
L
D
M
T
A
V
Site 12
S109
C
G
I
N
P
E
K
S
I
L
F
Q
Q
S
Q
Site 13
S115
K
S
I
L
F
Q
Q
S
Q
V
S
E
H
T
Q
Site 14
S118
L
F
Q
Q
S
Q
V
S
E
H
T
Q
L
S
W
Site 15
T154
T
K
Q
K
H
D
G
T
V
G
L
L
T
Y
P
Site 16
T174
D
I
L
L
Y
K
S
T
H
V
P
V
G
E
D
Site 17
Y200
A
Q
G
F
N
K
K
Y
G
E
F
F
P
V
P
Site 18
S209
E
F
F
P
V
P
E
S
I
L
T
S
M
K
K
Site 19
T212
P
V
P
E
S
I
L
T
S
M
K
K
V
K
S
Site 20
S213
V
P
E
S
I
L
T
S
M
K
K
V
K
S
L
Site 21
S219
T
S
M
K
K
V
K
S
L
R
D
P
S
A
K
Site 22
S224
V
K
S
L
R
D
P
S
A
K
M
S
K
S
D
Site 23
S228
R
D
P
S
A
K
M
S
K
S
D
P
D
K
L
Site 24
S230
P
S
A
K
M
S
K
S
D
P
D
K
L
A
T
Site 25
T237
S
D
P
D
K
L
A
T
V
R
I
T
D
S
P
Site 26
T241
K
L
A
T
V
R
I
T
D
S
P
E
E
I
V
Site 27
S243
A
T
V
R
I
T
D
S
P
E
E
I
V
Q
K
Site 28
T259
R
K
A
V
T
D
F
T
S
E
V
T
Y
D
P
Site 29
Y264
D
F
T
S
E
V
T
Y
D
P
A
G
R
A
G
Site 30
S294
V
E
E
V
V
R
R
S
A
G
M
N
T
A
R
Site 31
T299
R
R
S
A
G
M
N
T
A
R
Y
K
L
A
V
Site 32
T348
K
A
K
E
L
A
Y
T
V
C
Q
E
V
K
K
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation