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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
LIMD1
Full Name:
LIM domain-containing protein 1
Alias:
LIM domains containing 1; LIM domains containing protein 1; LIMD
Type:
Tumor suppressor
Mass (Da):
72190
Number AA:
676
UniProt ID:
Q9UGP4
International Prot ID:
IPI00003369
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
GO:0005488
GO:0005515
GO:0008270
PhosphoSite+
KinaseNET
Biological Process:
GO:0006355
GO:0007154
GO:0007165
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S12
D
D
L
G
L
E
A
S
K
F
I
E
D
L
N
Site 2
Y21
F
I
E
D
L
N
M
Y
E
A
S
K
D
G
L
Site 3
S24
D
L
N
M
Y
E
A
S
K
D
G
L
F
R
V
Site 4
T44
N
N
P
E
F
E
E
T
R
R
V
F
A
T
K
Site 5
T50
E
T
R
R
V
F
A
T
K
M
A
K
I
H
L
Site 6
T69
Q
Q
L
L
Q
E
E
T
L
P
R
G
S
R
G
Site 7
S74
E
E
T
L
P
R
G
S
R
G
P
V
N
G
G
Site 8
Y127
L
A
A
G
Q
P
P
Y
P
P
Q
E
Q
R
S
Site 9
Y137
Q
E
Q
R
S
R
P
Y
L
H
G
T
R
H
G
Site 10
T141
S
R
P
Y
L
H
G
T
R
H
G
S
Q
D
C
Site 11
S145
L
H
G
T
R
H
G
S
Q
D
C
G
S
R
E
Site 12
S150
H
G
S
Q
D
C
G
S
R
E
S
L
A
T
S
Site 13
S153
Q
D
C
G
S
R
E
S
L
A
T
S
E
M
S
Site 14
T156
G
S
R
E
S
L
A
T
S
E
M
S
A
F
H
Site 15
S157
S
R
E
S
L
A
T
S
E
M
S
A
F
H
Q
Site 16
S172
P
G
P
C
E
D
P
S
C
L
T
H
G
D
Y
Site 17
Y179
S
C
L
T
H
G
D
Y
Y
D
N
L
S
L
A
Site 18
Y180
C
L
T
H
G
D
Y
Y
D
N
L
S
L
A
S
Site 19
S184
G
D
Y
Y
D
N
L
S
L
A
S
P
K
W
G
Site 20
S187
Y
D
N
L
S
L
A
S
P
K
W
G
D
K
P
Site 21
S197
W
G
D
K
P
G
V
S
P
S
I
G
L
S
V
Site 22
S199
D
K
P
G
V
S
P
S
I
G
L
S
V
G
S
Site 23
S206
S
I
G
L
S
V
G
S
G
W
P
S
S
P
G
Site 24
S210
S
V
G
S
G
W
P
S
S
P
G
S
D
P
P
Site 25
S211
V
G
S
G
W
P
S
S
P
G
S
D
P
P
L
Site 26
S214
G
W
P
S
S
P
G
S
D
P
P
L
P
K
P
Site 27
S233
P
L
N
H
R
Q
L
S
L
S
S
S
R
S
S
Site 28
S235
N
H
R
Q
L
S
L
S
S
S
R
S
S
E
G
Site 29
S236
H
R
Q
L
S
L
S
S
S
R
S
S
E
G
S
Site 30
S237
R
Q
L
S
L
S
S
S
R
S
S
E
G
S
L
Site 31
S239
L
S
L
S
S
S
R
S
S
E
G
S
L
G
G
Site 32
S240
S
L
S
S
S
R
S
S
E
G
S
L
G
G
Q
Site 33
S243
S
S
R
S
S
E
G
S
L
G
G
Q
N
S
G
Site 34
S249
G
S
L
G
G
Q
N
S
G
I
G
G
R
S
S
Site 35
S256
S
G
I
G
G
R
S
S
E
K
P
T
G
L
W
Site 36
T260
G
R
S
S
E
K
P
T
G
L
W
S
T
A
S
Site 37
S264
E
K
P
T
G
L
W
S
T
A
S
S
Q
R
V
Site 38
S267
T
G
L
W
S
T
A
S
S
Q
R
V
S
P
G
Site 39
S268
G
L
W
S
T
A
S
S
Q
R
V
S
P
G
L
Site 40
S272
T
A
S
S
Q
R
V
S
P
G
L
P
S
P
N
Site 41
S277
R
V
S
P
G
L
P
S
P
N
L
E
N
G
A
Site 42
T294
V
G
P
V
Q
P
R
T
P
S
V
S
A
P
L
Site 43
S296
P
V
Q
P
R
T
P
S
V
S
A
P
L
A
L
Site 44
S298
Q
P
R
T
P
S
V
S
A
P
L
A
L
S
C
Site 45
S304
V
S
A
P
L
A
L
S
C
P
R
Q
G
G
L
Site 46
S314
R
Q
G
G
L
P
R
S
N
S
G
L
G
G
E
Site 47
S316
G
G
L
P
R
S
N
S
G
L
G
G
E
V
S
Site 48
S323
S
G
L
G
G
E
V
S
G
V
M
S
K
P
N
Site 49
S327
G
E
V
S
G
V
M
S
K
P
N
V
D
P
Q
Site 50
S343
W
F
Q
D
G
P
K
S
Y
L
S
S
S
A
P
Site 51
Y344
F
Q
D
G
P
K
S
Y
L
S
S
S
A
P
S
Site 52
S346
D
G
P
K
S
Y
L
S
S
S
A
P
S
S
S
Site 53
S347
G
P
K
S
Y
L
S
S
S
A
P
S
S
S
P
Site 54
S348
P
K
S
Y
L
S
S
S
A
P
S
S
S
P
A
Site 55
S351
Y
L
S
S
S
A
P
S
S
S
P
A
G
L
D
Site 56
S352
L
S
S
S
A
P
S
S
S
P
A
G
L
D
G
Site 57
S353
S
S
S
A
P
S
S
S
P
A
G
L
D
G
S
Site 58
S360
S
P
A
G
L
D
G
S
Q
Q
G
A
V
P
G
Site 59
T375
L
G
P
K
P
G
C
T
D
L
G
T
G
P
K
Site 60
T379
P
G
C
T
D
L
G
T
G
P
K
L
S
P
T
Site 61
S384
L
G
T
G
P
K
L
S
P
T
S
L
V
H
P
Site 62
S387
G
P
K
L
S
P
T
S
L
V
H
P
V
M
S
Site 63
S400
M
S
T
L
P
E
L
S
C
K
E
G
P
L
G
Site 64
S409
K
E
G
P
L
G
W
S
S
D
G
S
L
G
S
Site 65
S410
E
G
P
L
G
W
S
S
D
G
S
L
G
S
V
Site 66
S416
S
S
D
G
S
L
G
S
V
L
L
D
S
P
S
Site 67
S421
L
G
S
V
L
L
D
S
P
S
S
P
R
V
R
Site 68
S423
S
V
L
L
D
S
P
S
S
P
R
V
R
L
P
Site 69
S424
V
L
L
D
S
P
S
S
P
R
V
R
L
P
C
Site 70
S443
P
G
P
E
L
R
P
S
A
A
E
L
K
L
E
Site 71
Y468
D
A
H
P
K
A
D
Y
F
G
A
C
V
K
C
Site 72
Y527
F
C
E
E
D
F
L
Y
S
G
F
Q
Q
S
A
Site 73
T576
C
L
D
G
V
P
F
T
V
D
S
E
N
K
I
Site 74
Y584
V
D
S
E
N
K
I
Y
C
V
R
D
Y
H
K
Site 75
Y589
K
I
Y
C
V
R
D
Y
H
K
V
L
A
P
K
Site 76
S610
P
I
L
P
P
E
G
S
D
E
T
I
R
V
V
Site 77
T613
P
P
E
G
S
D
E
T
I
R
V
V
S
M
D
Site 78
S618
D
E
T
I
R
V
V
S
M
D
R
D
Y
H
V
Site 79
Y646
D
E
D
G
H
R
C
Y
P
L
E
D
H
L
F
Site 80
S667
K
R
L
E
K
R
P
S
S
T
A
L
H
Q
H
Site 81
S668
R
L
E
K
R
P
S
S
T
A
L
H
Q
H
H
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation