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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
ZC3H7B
Full Name:
Zinc finger CCCH domain-containing protein 7B
Alias:
Rotavirus 'X'-associated non-structural protein; Zinc finger CCCH domain-containing protein 7B: Rotavirus 'X'-associated non-structural protein: Zinc finger CCCH domain-containing protein 7B: Rotavirus 'X'-associated non-structural protein
Type:
DNA binding protein
Mass (Da):
111578
Number AA:
993
UniProt ID:
Q9UGR2
International Prot ID:
IPI00099131
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005622
GO:0005634
GO:0043226
Uniprot
OncoNet
Molecular Function:
GO:0003676
GO:0005488
GO:0005515
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S19
K
G
L
Q
F
I
Q
S
T
L
P
L
K
Q
E
Site 2
Y28
L
P
L
K
Q
E
E
Y
E
A
F
L
L
K
L
Site 3
Y52
D
L
F
R
E
K
D
Y
K
Q
A
L
V
Q
Y
Site 4
Y68
E
G
L
N
V
A
D
Y
A
A
S
D
Q
V
A
Site 5
Y92
H
V
N
R
A
A
C
Y
F
T
M
G
L
Y
E
Site 6
S105
Y
E
K
A
L
E
D
S
E
K
A
L
G
L
D
Site 7
S113
E
K
A
L
G
L
D
S
E
S
I
R
A
L
F
Site 8
S115
A
L
G
L
D
S
E
S
I
R
A
L
F
R
K
Site 9
Y136
L
G
R
H
K
E
A
Y
E
C
S
S
R
C
S
Site 10
S139
H
K
E
A
Y
E
C
S
S
R
C
S
L
A
L
Site 11
S143
Y
E
C
S
S
R
C
S
L
A
L
P
H
D
E
Site 12
S151
L
A
L
P
H
D
E
S
V
T
Q
L
G
Q
E
Site 13
Y171
G
L
R
V
R
K
A
Y
K
R
P
Q
E
L
E
Site 14
T179
K
R
P
Q
E
L
E
T
F
S
L
L
S
N
G
Site 15
S181
P
Q
E
L
E
T
F
S
L
L
S
N
G
T
A
Site 16
T196
A
G
V
A
D
Q
G
T
S
N
G
L
G
S
I
Site 17
S197
G
V
A
D
Q
G
T
S
N
G
L
G
S
I
D
Site 18
S202
G
T
S
N
G
L
G
S
I
D
D
I
E
T
G
Site 19
T208
G
S
I
D
D
I
E
T
G
N
V
P
D
T
R
Site 20
T214
E
T
G
N
V
P
D
T
R
E
Q
V
E
I
G
Site 21
Y227
I
G
A
P
R
D
C
Y
V
D
P
R
G
S
P
Site 22
S233
C
Y
V
D
P
R
G
S
P
A
L
L
P
S
T
Site 23
S239
G
S
P
A
L
L
P
S
T
P
T
M
P
L
F
Site 24
T240
S
P
A
L
L
P
S
T
P
T
M
P
L
F
P
Site 25
T242
A
L
L
P
S
T
P
T
M
P
L
F
P
H
V
Site 26
S258
D
L
L
A
P
L
D
S
S
R
T
L
P
S
T
Site 27
S259
L
L
A
P
L
D
S
S
R
T
L
P
S
T
D
Site 28
T261
A
P
L
D
S
S
R
T
L
P
S
T
D
S
L
Site 29
S264
D
S
S
R
T
L
P
S
T
D
S
L
D
D
F
Site 30
T265
S
S
R
T
L
P
S
T
D
S
L
D
D
F
S
Site 31
S267
R
T
L
P
S
T
D
S
L
D
D
F
S
D
G
Site 32
S272
T
D
S
L
D
D
F
S
D
G
D
V
F
G
P
Site 33
S296
S
L
V
Q
G
G
L
S
G
S
G
V
P
S
E
Site 34
S298
V
Q
G
G
L
S
G
S
G
V
P
S
E
L
P
Site 35
S350
P
S
K
K
L
A
A
S
V
L
D
A
L
D
P
Site 36
S371
P
L
D
L
L
P
Y
S
E
T
R
L
D
A
L
Site 37
S380
T
R
L
D
A
L
D
S
F
G
S
T
R
G
S
Site 38
S383
D
A
L
D
S
F
G
S
T
R
G
S
L
D
K
Site 39
S387
S
F
G
S
T
R
G
S
L
D
K
P
D
S
F
Site 40
S393
G
S
L
D
K
P
D
S
F
M
E
E
T
N
S
Site 41
S400
S
F
M
E
E
T
N
S
Q
D
H
R
P
P
S
Site 42
S407
S
Q
D
H
R
P
P
S
G
A
Q
K
P
A
P
Site 43
S415
G
A
Q
K
P
A
P
S
P
E
P
C
M
P
N
Site 44
Y445
K
Q
A
C
Q
L
C
Y
P
K
T
G
P
R
A
Site 45
T448
C
Q
L
C
Y
P
K
T
G
P
R
A
G
D
Y
Site 46
Y455
T
G
P
R
A
G
D
Y
T
Y
R
E
G
L
E
Site 47
T456
G
P
R
A
G
D
Y
T
Y
R
E
G
L
E
H
Site 48
Y457
P
R
A
G
D
Y
T
Y
R
E
G
L
E
H
K
Site 49
S476
I
L
L
G
R
L
R
S
S
E
D
Q
T
W
K
Site 50
S477
L
L
G
R
L
R
S
S
E
D
Q
T
W
K
R
Site 51
T481
L
R
S
S
E
D
Q
T
W
K
R
I
R
P
R
Site 52
T490
K
R
I
R
P
R
P
T
K
T
S
F
V
G
S
Site 53
T492
I
R
P
R
P
T
K
T
S
F
V
G
S
Y
Y
Site 54
S493
R
P
R
P
T
K
T
S
F
V
G
S
Y
Y
L
Site 55
Y512
I
N
K
Q
D
C
K
Y
G
D
N
C
T
F
A
Site 56
T529
Q
E
E
I
D
V
W
T
E
E
R
K
G
T
L
Site 57
T535
W
T
E
E
R
K
G
T
L
N
R
D
L
L
F
Site 58
T554
G
V
K
R
G
S
L
T
I
A
K
L
L
K
E
Site 59
S582
D
S
K
P
R
I
I
S
K
G
T
K
D
S
P
Site 60
S588
I
S
K
G
T
K
D
S
P
S
V
C
S
N
L
Site 61
S590
K
G
T
K
D
S
P
S
V
C
S
N
L
A
A
Site 62
Y602
L
A
A
K
H
S
F
Y
N
N
K
C
L
V
H
Site 63
S615
V
H
I
V
R
S
T
S
L
K
Y
S
K
I
R
Site 64
S619
R
S
T
S
L
K
Y
S
K
I
R
Q
F
Q
E
Site 65
Y639
V
C
R
H
E
V
R
Y
G
C
L
R
E
D
S
Site 66
Y664
K
V
W
L
L
Q
Q
Y
S
G
M
T
H
E
D
Site 67
Y679
I
V
Q
E
S
K
K
Y
W
Q
Q
M
E
A
H
Site 68
S693
H
A
G
K
A
S
S
S
M
G
A
P
R
T
H
Site 69
T699
S
S
M
G
A
P
R
T
H
G
P
S
T
F
D
Site 70
S703
A
P
R
T
H
G
P
S
T
F
D
L
Q
M
K
Site 71
T704
P
R
T
H
G
P
S
T
F
D
L
Q
M
K
F
Site 72
Y731
E
P
D
K
D
L
K
Y
C
S
A
K
A
R
H
Site 73
S751
R
R
V
L
L
V
M
S
K
A
K
R
K
W
V
Site 74
S759
K
A
K
R
K
W
V
S
V
R
P
L
P
S
I
Site 75
S765
V
S
V
R
P
L
P
S
I
R
N
F
P
Q
Q
Site 76
Y787
Q
N
G
R
K
C
Q
Y
V
G
N
C
S
F
A
Site 77
S796
G
N
C
S
F
A
H
S
P
E
E
R
D
M
W
Site 78
T834
P
G
K
P
G
E
G
T
P
I
S
S
R
E
G
Site 79
S837
P
G
E
G
T
P
I
S
S
R
E
G
E
K
Q
Site 80
Y851
Q
I
Q
M
P
T
D
Y
A
D
I
M
M
G
Y
Site 81
T888
K
H
K
E
K
V
F
T
S
D
S
D
A
S
G
Site 82
S889
H
K
E
K
V
F
T
S
D
S
D
A
S
G
W
Site 83
S891
E
K
V
F
T
S
D
S
D
A
S
G
W
A
F
Site 84
Y965
R
D
D
D
F
G
K
Y
N
F
L
L
Q
E
D
Site 85
T979
D
G
D
L
A
G
A
T
P
E
A
P
A
A
A
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation