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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
TCF20
Full Name:
Transcription factor 20
Alias:
AR1; KIAA0292; nuclear factor SPBP; SPBP; SPRE-binding protein; stromelysin 1 PDGF-responsive element-binding protein; stromelysin-1 platelet-derived growth factor-responsive element binding protein; TF20; transcription factor 20
Type:
Nuclear receptor co-regulator; Transcription factor
Mass (Da):
211771
Number AA:
1960
UniProt ID:
Q9UGU0
International Prot ID:
IPI00159322
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005634
Uniprot
OncoNet
Molecular Function:
GO:0003677
GO:0003713
GO:0008270
PhosphoSite+
KinaseNET
Biological Process:
GO:0006355
GO:0006350
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S8
M
Q
S
F
R
E
Q
S
S
Y
H
G
N
Q
Q
Site 2
S9
Q
S
F
R
E
Q
S
S
Y
H
G
N
Q
Q
S
Site 3
Y10
S
F
R
E
Q
S
S
Y
H
G
N
Q
Q
S
Y
Site 4
S16
S
Y
H
G
N
Q
Q
S
Y
P
Q
E
V
H
G
Site 5
Y17
Y
H
G
N
Q
Q
S
Y
P
Q
E
V
H
G
S
Site 6
S24
Y
P
Q
E
V
H
G
S
S
R
L
E
E
F
S
Site 7
S31
S
S
R
L
E
E
F
S
P
R
Q
A
Q
M
F
Site 8
T44
M
F
Q
N
F
G
G
T
G
G
S
S
G
S
S
Site 9
S47
N
F
G
G
T
G
G
S
S
G
S
S
G
S
G
Site 10
S48
F
G
G
T
G
G
S
S
G
S
S
G
S
G
S
Site 11
S50
G
T
G
G
S
S
G
S
S
G
S
G
S
G
G
Site 12
S51
T
G
G
S
S
G
S
S
G
S
G
S
G
G
G
Site 13
S53
G
S
S
G
S
S
G
S
G
S
G
G
G
R
R
Site 14
S55
S
G
S
S
G
S
G
S
G
G
G
R
R
G
A
Site 15
S71
A
A
A
A
A
M
A
S
E
T
S
G
H
Q
G
Site 16
Y90
R
K
E
A
G
D
F
Y
Y
M
A
G
N
K
D
Site 17
Y91
K
E
A
G
D
F
Y
Y
M
A
G
N
K
D
P
Site 18
T100
A
G
N
K
D
P
V
T
T
G
T
P
Q
P
P
Site 19
T101
G
N
K
D
P
V
T
T
G
T
P
Q
P
P
Q
Site 20
T103
K
D
P
V
T
T
G
T
P
Q
P
P
Q
R
R
Site 21
S112
Q
P
P
Q
R
R
P
S
G
P
V
Q
S
Y
G
Site 22
S117
R
P
S
G
P
V
Q
S
Y
G
P
P
Q
G
S
Site 23
Y118
P
S
G
P
V
Q
S
Y
G
P
P
Q
G
S
S
Site 24
S124
S
Y
G
P
P
Q
G
S
S
F
G
N
Q
Y
G
Site 25
S125
Y
G
P
P
Q
G
S
S
F
G
N
Q
Y
G
S
Site 26
Y130
G
S
S
F
G
N
Q
Y
G
S
E
G
H
V
G
Site 27
S132
S
F
G
N
Q
Y
G
S
E
G
H
V
G
Q
F
Site 28
Y152
G
L
G
G
V
S
H
Y
Q
Q
D
Y
T
G
P
Site 29
Y156
V
S
H
Y
Q
Q
D
Y
T
G
P
F
S
P
G
Site 30
T157
S
H
Y
Q
Q
D
Y
T
G
P
F
S
P
G
S
Site 31
S161
Q
D
Y
T
G
P
F
S
P
G
S
A
Q
Y
Q
Site 32
S164
T
G
P
F
S
P
G
S
A
Q
Y
Q
Q
Q
A
Site 33
S173
Q
Y
Q
Q
Q
A
S
S
Q
Q
Q
Q
Q
Q
V
Site 34
Y188
Q
Q
L
R
Q
Q
L
Y
Q
S
H
Q
P
L
P
Site 35
S190
L
R
Q
Q
L
Y
Q
S
H
Q
P
L
P
Q
A
Site 36
S203
Q
A
T
G
Q
P
A
S
S
S
S
H
L
Q
P
Site 37
S204
A
T
G
Q
P
A
S
S
S
S
H
L
Q
P
M
Site 38
S205
T
G
Q
P
A
S
S
S
S
H
L
Q
P
M
Q
Site 39
S215
L
Q
P
M
Q
R
P
S
T
L
P
S
S
A
A
Site 40
T216
Q
P
M
Q
R
P
S
T
L
P
S
S
A
A
G
Site 41
S219
Q
R
P
S
T
L
P
S
S
A
A
G
Y
Q
L
Site 42
S220
R
P
S
T
L
P
S
S
A
A
G
Y
Q
L
R
Site 43
Y224
L
P
S
S
A
A
G
Y
Q
L
R
V
G
Q
F
Site 44
Y235
V
G
Q
F
G
Q
H
Y
Q
S
S
A
S
S
S
Site 45
S237
Q
F
G
Q
H
Y
Q
S
S
A
S
S
S
S
S
Site 46
S238
F
G
Q
H
Y
Q
S
S
A
S
S
S
S
S
S
Site 47
S240
Q
H
Y
Q
S
S
A
S
S
S
S
S
S
S
F
Site 48
S241
H
Y
Q
S
S
A
S
S
S
S
S
S
S
F
P
Site 49
S242
Y
Q
S
S
A
S
S
S
S
S
S
S
F
P
S
Site 50
S243
Q
S
S
A
S
S
S
S
S
S
S
F
P
S
P
Site 51
S244
S
S
A
S
S
S
S
S
S
S
F
P
S
P
Q
Site 52
S245
S
A
S
S
S
S
S
S
S
F
P
S
P
Q
R
Site 53
S246
A
S
S
S
S
S
S
S
F
P
S
P
Q
R
F
Site 54
S249
S
S
S
S
S
F
P
S
P
Q
R
F
S
Q
S
Site 55
S254
F
P
S
P
Q
R
F
S
Q
S
G
Q
S
Y
D
Site 56
S256
S
P
Q
R
F
S
Q
S
G
Q
S
Y
D
G
S
Site 57
S259
R
F
S
Q
S
G
Q
S
Y
D
G
S
Y
N
V
Site 58
Y260
F
S
Q
S
G
Q
S
Y
D
G
S
Y
N
V
N
Site 59
S263
S
G
Q
S
Y
D
G
S
Y
N
V
N
A
G
S
Site 60
Y264
G
Q
S
Y
D
G
S
Y
N
V
N
A
G
S
Q
Site 61
S270
S
Y
N
V
N
A
G
S
Q
Y
E
G
H
N
V
Site 62
Y284
V
G
S
N
A
Q
A
Y
G
T
Q
S
N
Y
S
Site 63
T286
S
N
A
Q
A
Y
G
T
Q
S
N
Y
S
Y
Q
Site 64
S288
A
Q
A
Y
G
T
Q
S
N
Y
S
Y
Q
P
Q
Site 65
S291
Y
G
T
Q
S
N
Y
S
Y
Q
P
Q
S
M
K
Site 66
Y292
G
T
Q
S
N
Y
S
Y
Q
P
Q
S
M
K
N
Site 67
S342
A
T
K
L
P
L
Q
S
Q
V
G
Q
Y
N
Q
Site 68
Y347
L
Q
S
Q
V
G
Q
Y
N
Q
P
E
V
P
V
Site 69
S356
Q
P
E
V
P
V
R
S
P
M
Q
F
H
Q
N
Site 70
S365
M
Q
F
H
Q
N
F
S
P
I
S
N
P
S
P
Site 71
S368
H
Q
N
F
S
P
I
S
N
P
S
P
A
A
S
Site 72
S375
S
N
P
S
P
A
A
S
V
V
Q
S
P
S
C
Site 73
S379
P
A
A
S
V
V
Q
S
P
S
C
S
S
T
P
Site 74
S381
A
S
V
V
Q
S
P
S
C
S
S
T
P
S
P
Site 75
S383
V
V
Q
S
P
S
C
S
S
T
P
S
P
L
M
Site 76
S384
V
Q
S
P
S
C
S
S
T
P
S
P
L
M
Q
Site 77
T385
Q
S
P
S
C
S
S
T
P
S
P
L
M
Q
T
Site 78
S387
P
S
C
S
S
T
P
S
P
L
M
Q
T
G
E
Site 79
S402
N
L
Q
C
G
Q
G
S
V
P
M
G
S
R
N
Site 80
S407
Q
G
S
V
P
M
G
S
R
N
R
I
L
Q
L
Site 81
S419
L
Q
L
M
P
Q
L
S
P
T
P
S
M
M
P
Site 82
T421
L
M
P
Q
L
S
P
T
P
S
M
M
P
S
P
Site 83
S423
P
Q
L
S
P
T
P
S
M
M
P
S
P
N
S
Site 84
S427
P
T
P
S
M
M
P
S
P
N
S
H
A
A
G
Site 85
S430
S
M
M
P
S
P
N
S
H
A
A
G
F
K
G
Site 86
T449
G
V
P
E
K
R
L
T
D
P
G
L
S
S
L
Site 87
S454
R
L
T
D
P
G
L
S
S
L
S
A
L
S
T
Site 88
S455
L
T
D
P
G
L
S
S
L
S
A
L
S
T
Q
Site 89
T461
S
S
L
S
A
L
S
T
Q
V
A
N
L
P
N
Site 90
T469
Q
V
A
N
L
P
N
T
V
Q
H
M
L
L
S
Site 91
S476
T
V
Q
H
M
L
L
S
D
A
L
T
P
Q
K
Site 92
T480
M
L
L
S
D
A
L
T
P
Q
K
K
T
S
K
Site 93
T485
A
L
T
P
Q
K
K
T
S
K
R
P
S
S
S
Site 94
S486
L
T
P
Q
K
K
T
S
K
R
P
S
S
S
K
Site 95
S490
K
K
T
S
K
R
P
S
S
S
K
K
A
D
S
Site 96
S491
K
T
S
K
R
P
S
S
S
K
K
A
D
S
C
Site 97
S492
T
S
K
R
P
S
S
S
K
K
A
D
S
C
T
Site 98
S497
S
S
S
K
K
A
D
S
C
T
N
S
E
G
S
Site 99
T499
S
K
K
A
D
S
C
T
N
S
E
G
S
S
Q
Site 100
S501
K
A
D
S
C
T
N
S
E
G
S
S
Q
P
E
Site 101
S505
C
T
N
S
E
G
S
S
Q
P
E
E
Q
L
K
Site 102
S513
Q
P
E
E
Q
L
K
S
P
M
A
E
S
L
D
Site 103
S518
L
K
S
P
M
A
E
S
L
D
G
G
C
S
S
Site 104
S524
E
S
L
D
G
G
C
S
S
S
S
E
D
Q
G
Site 105
S525
S
L
D
G
G
C
S
S
S
S
E
D
Q
G
E
Site 106
S526
L
D
G
G
C
S
S
S
S
E
D
Q
G
E
R
Site 107
S527
D
G
G
C
S
S
S
S
E
D
Q
G
E
R
V
Site 108
S538
G
E
R
V
R
Q
L
S
G
Q
S
T
S
S
D
Site 109
S541
V
R
Q
L
S
G
Q
S
T
S
S
D
T
T
Y
Site 110
T542
R
Q
L
S
G
Q
S
T
S
S
D
T
T
Y
K
Site 111
S544
L
S
G
Q
S
T
S
S
D
T
T
Y
K
G
G
Site 112
T546
G
Q
S
T
S
S
D
T
T
Y
K
G
G
A
S
Site 113
T547
Q
S
T
S
S
D
T
T
Y
K
G
G
A
S
E
Site 114
Y548
S
T
S
S
D
T
T
Y
K
G
G
A
S
E
K
Site 115
S558
G
A
S
E
K
A
G
S
S
P
A
Q
G
A
Q
Site 116
S559
A
S
E
K
A
G
S
S
P
A
Q
G
A
Q
N
Site 117
S574
E
P
P
R
L
N
A
S
P
A
A
R
E
E
A
Site 118
T582
P
A
A
R
E
E
A
T
S
P
G
A
K
D
M
Site 119
S583
A
A
R
E
E
A
T
S
P
G
A
K
D
M
P
Site 120
S592
G
A
K
D
M
P
L
S
S
D
G
N
P
K
V
Site 121
S593
A
K
D
M
P
L
S
S
D
G
N
P
K
V
N
Site 122
T603
N
P
K
V
N
E
K
T
V
G
V
I
V
S
R
Site 123
S627
P
G
G
Q
D
K
G
S
Q
E
D
D
P
A
A
Site 124
T635
Q
E
D
D
P
A
A
T
Q
R
P
P
S
N
G
Site 125
S640
A
A
T
Q
R
P
P
S
N
G
G
A
K
E
T
Site 126
S648
N
G
G
A
K
E
T
S
H
A
S
L
P
Q
P
Site 127
S651
A
K
E
T
S
H
A
S
L
P
Q
P
E
P
P
Site 128
S663
E
P
P
G
G
G
G
S
K
G
N
K
N
G
D
Site 129
S683
N
G
E
G
N
G
Q
S
G
H
S
A
A
G
P
Site 130
S686
G
N
G
Q
S
G
H
S
A
A
G
P
G
F
T
Site 131
T693
S
A
A
G
P
G
F
T
S
R
T
E
P
S
K
Site 132
S694
A
A
G
P
G
F
T
S
R
T
E
P
S
K
S
Site 133
T696
G
P
G
F
T
S
R
T
E
P
S
K
S
P
G
Site 134
S699
F
T
S
R
T
E
P
S
K
S
P
G
S
L
R
Site 135
S701
S
R
T
E
P
S
K
S
P
G
S
L
R
Y
S
Site 136
S704
E
P
S
K
S
P
G
S
L
R
Y
S
Y
K
D
Site 137
S708
S
P
G
S
L
R
Y
S
Y
K
D
S
F
G
S
Site 138
Y709
P
G
S
L
R
Y
S
Y
K
D
S
F
G
S
A
Site 139
S712
L
R
Y
S
Y
K
D
S
F
G
S
A
V
P
R
Site 140
S722
S
A
V
P
R
N
V
S
G
F
P
Q
Y
P
T
Site 141
Y727
N
V
S
G
F
P
Q
Y
P
T
G
Q
E
K
G
Site 142
T729
S
G
F
P
Q
Y
P
T
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V
L
D
S
K
P
S
Site 295
S1824
S
E
K
T
V
L
D
S
K
P
S
V
P
T
T
Site 296
S1827
T
V
L
D
S
K
P
S
V
P
T
T
S
E
G
Site 297
T1831
S
K
P
S
V
P
T
T
S
E
G
G
P
E
L
Site 298
S1849
I
P
E
L
P
L
D
S
N
E
F
W
V
H
E
Site 299
Y1900
A
G
A
T
L
G
C
Y
N
K
G
C
S
F
R
Site 300
Y1910
G
C
S
F
R
Y
H
Y
P
C
A
I
D
A
D
Site 301
S1926
L
L
H
E
E
N
F
S
V
R
C
P
K
H
K
Site 302
T1947
L
P
P
L
Q
N
K
T
A
K
G
S
L
S
T
Site 303
S1951
Q
N
K
T
A
K
G
S
L
S
T
E
Q
S
E
Site 304
S1953
K
T
A
K
G
S
L
S
T
E
Q
S
E
R
G
Site 305
S1957
G
S
L
S
T
E
Q
S
E
R
G
_
_
_
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation