PhosphoNET

           
Protein Info 
   
Short Name:  NDRG3
Full Name:  Protein NDRG3
Alias:  NDRG family member 3; N-myc downstream-regulated gene 3
Type:  Cell development/differentiation
Mass (Da):  41409
Number AA:  375
UniProt ID:  Q9UGV2
International Prot ID:  IPI00005605
Sequence:  Retrieve full protein sequence
   
GO Terms  External Links Internal Links  
   
Cellular Component:  GO:0005737     Uniprot OncoNet
Molecular Function:      PhosphoSite+ KinaseNET
Biological Process:  GO:0030154  GO:0030308  GO:0007283 Phosida TranscriptoNet
    STRING Kinexus Products
   
Info Box  A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites 
-7-6-5-4-3-2-101234567Expt. conf.EffectKinasePPaseKinexus ProductsRef.Evol.Kinase Pred.P-site Match
Site 1T59GNRPVILTYHDIGLN
Site 2Y60NRPVILTYHDIGLNH
Site 3S103GQQEGAPSFPTGYQY
Site 4Y108APSFPTGYQYPTMDE
Site 5Y110SFPTGYQYPTMDELA
Site 6Y229LQLFLNSYNGRRDLE
Site 7S249LGQNDNKSKTLKCST
Site 8T251QNDNKSKTLKCSTLL
Site 9Y308KLTEAFKYFLQGMGY
Site 10Y315YFLQGMGYIPSASMT
Site 11S318QGMGYIPSASMTRLA
Site 12S320MGYIPSASMTRLARS
Site 13T322YIPSASMTRLARSRT
Site 14S327SMTRLARSRTHSTSS
Site 15T329TRLARSRTHSTSSSL
Site 16S331LARSRTHSTSSSLGS
Site 17T332ARSRTHSTSSSLGSG
Site 18S333RSRTHSTSSSLGSGE
Site 19S334SRTHSTSSSLGSGES
Site 20S335RTHSTSSSLGSGESP
Site 21S338STSSSLGSGESPFSR
Site 22S341SSLGSGESPFSRSVT
Site 23S344GSGESPFSRSVTSNQ
Site 24S346GESPFSRSVTSNQSD
Site 25T348SPFSRSVTSNQSDGT
Site 26S349PFSRSVTSNQSDGTQ
Site 27S352RSVTSNQSDGTQESC
Site 28T355TSNQSDGTQESCESP
Site 29S358QSDGTQESCESPDVL
Site 30S361GTQESCESPDVLDRH
Site 31T370DVLDRHQTMEVSC__
Site 32S374RHQTMEVSC______
 
Legend 
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available  
Products available
 


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