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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
SWAP70
Full Name:
Switch-associated protein 70
Alias:
KIAA0640; SWAP switching B-cell complex 70kDa subunit; SWAP-70; SWP70
Type:
Guanine nucleotide exchange factor, Rac/Rho
Mass (Da):
68998
Number AA:
585
UniProt ID:
Q9UH65
International Prot ID:
IPI00307200
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005737
GO:0030027
GO:0005634
Uniprot
OncoNet
Molecular Function:
GO:0003677
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S3
_
_
_
_
_
M
G
S
L
K
E
E
L
L
K
Site 2
S24
T
A
L
D
Q
D
H
S
G
K
V
S
K
S
Q
Site 3
S28
Q
D
H
S
G
K
V
S
K
S
Q
L
K
V
L
Site 4
S30
H
S
G
K
V
S
K
S
Q
L
K
V
L
S
H
Site 5
S65
D
D
D
E
G
P
V
S
N
Q
G
Y
M
P
Y
Site 6
Y69
G
P
V
S
N
Q
G
Y
M
P
Y
L
N
R
F
Site 7
Y72
S
N
Q
G
Y
M
P
Y
L
N
R
F
I
L
E
Site 8
Y130
N
F
L
S
E
D
K
Y
P
L
I
I
V
S
E
Site 9
Y141
I
V
S
E
E
I
E
Y
L
L
K
K
L
T
E
Site 10
T147
E
Y
L
L
K
K
L
T
E
A
M
G
G
G
W
Site 11
T195
S
K
G
M
D
R
Q
T
V
S
M
A
I
N
E
Site 12
Y216
L
D
V
L
K
Q
G
Y
M
M
K
K
G
H
R
Site 13
Y241
L
K
P
N
I
I
S
Y
Y
V
S
E
D
L
K
Site 14
Y242
K
P
N
I
I
S
Y
Y
V
S
E
D
L
K
D
Site 15
S244
N
I
I
S
Y
Y
V
S
E
D
L
K
D
K
K
Site 16
T283
L
V
K
C
F
D
K
T
F
E
I
S
A
S
D
Site 17
S289
K
T
F
E
I
S
A
S
D
K
K
K
K
Q
E
Site 18
S312
I
H
L
L
K
L
G
S
P
P
P
H
K
E
A
Site 19
S367
K
K
L
E
E
A
A
S
R
A
A
E
E
E
K
Site 20
T379
E
E
K
K
R
L
Q
T
Q
V
E
L
Q
A
R
Site 21
S388
V
E
L
Q
A
R
F
S
T
E
L
E
R
E
K
Site 22
T389
E
L
Q
A
R
F
S
T
E
L
E
R
E
K
L
Site 23
S409
E
E
Q
V
A
Q
K
S
S
E
L
E
Q
Y
L
Site 24
Y415
K
S
S
E
L
E
Q
Y
L
Q
R
V
R
E
L
Site 25
Y426
V
R
E
L
E
D
M
Y
L
K
L
Q
E
A
L
Site 26
T445
Q
A
R
Q
D
E
E
T
V
R
K
L
Q
A
R
Site 27
S459
R
L
L
E
E
E
S
S
K
R
A
E
L
E
K
Site 28
Y517
R
K
Q
A
L
E
Q
Y
E
E
V
K
K
K
L
Site 29
S533
M
A
T
N
K
T
K
S
W
K
D
K
V
A
H
Site 30
S552
I
R
L
I
E
P
G
S
K
N
P
H
L
I
T
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation