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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
FBXO40
Full Name:
Alias:
Muscle disease-related protein
Type:
Mass (Da):
79782
Number AA:
709
UniProt ID:
Q9UH90
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S7
_
M
G
K
A
R
R
S
P
P
G
H
H
R
H
Site 2
S68
E
Q
V
P
C
L
N
S
E
Y
G
C
P
L
S
Site 3
S75
S
E
Y
G
C
P
L
S
M
S
R
H
K
L
A
Site 4
T119
H
E
N
I
M
K
E
T
P
S
E
E
C
L
D
Site 5
T127
P
S
E
E
C
L
D
T
A
L
A
L
Q
D
Q
Site 6
T154
F
P
E
T
R
E
A
T
E
E
E
P
T
M
N
Site 7
T159
E
A
T
E
E
E
P
T
M
N
G
E
T
S
V
Site 8
S165
P
T
M
N
G
E
T
S
V
E
E
M
G
G
A
Site 9
S196
N
G
E
M
A
E
L
S
Q
E
E
R
E
V
L
Site 10
S229
F
S
K
E
H
A
A
S
A
L
T
N
S
S
A
Site 11
S234
A
A
S
A
L
T
N
S
S
A
S
C
E
S
K
Site 12
S235
A
S
A
L
T
N
S
S
A
S
C
E
S
K
N
Site 13
S237
A
L
T
N
S
S
A
S
C
E
S
K
N
K
N
Site 14
S246
E
S
K
N
K
N
D
S
E
K
E
Q
I
S
S
Site 15
S253
S
E
K
E
Q
I
S
S
G
H
N
M
V
E
G
Site 16
T284
D
V
R
T
A
M
E
T
T
G
L
A
P
W
Q
Site 17
T300
G
V
L
E
R
L
K
T
A
V
D
A
K
D
Y
Site 18
Y307
T
A
V
D
A
K
D
Y
N
M
Y
L
V
H
N
Site 19
Y310
D
A
K
D
Y
N
M
Y
L
V
H
N
G
R
M
Site 20
T328
F
G
Q
M
P
A
C
T
P
K
E
R
D
F
V
Site 21
Y336
P
K
E
R
D
F
V
Y
G
K
L
E
A
Q
E
Site 22
T346
L
E
A
Q
E
V
K
T
V
Y
T
F
K
V
P
Site 23
T349
Q
E
V
K
T
V
Y
T
F
K
V
P
V
S
Y
Site 24
S355
Y
T
F
K
V
P
V
S
Y
C
G
K
R
A
R
Site 25
S369
R
L
G
D
A
M
L
S
C
K
P
S
E
H
K
Site 26
S373
A
M
L
S
C
K
P
S
E
H
K
A
V
D
T
Site 27
S381
E
H
K
A
V
D
T
S
D
L
G
I
T
V
E
Site 28
T386
D
T
S
D
L
G
I
T
V
E
D
L
P
K
S
Site 29
S393
T
V
E
D
L
P
K
S
D
L
I
K
T
T
L
Site 30
S414
E
L
K
G
H
V
I
S
E
S
R
S
I
D
G
Site 31
S416
K
G
H
V
I
S
E
S
R
S
I
D
G
L
F
Site 32
S418
H
V
I
S
E
S
R
S
I
D
G
L
F
M
D
Site 33
S440
F
E
P
E
Q
F
S
S
G
T
V
L
A
D
L
Site 34
S461
G
L
H
V
E
L
H
S
E
C
V
T
R
R
H
Site 35
T465
E
L
H
S
E
C
V
T
R
R
H
N
K
S
S
Site 36
S471
V
T
R
R
H
N
K
S
S
S
A
F
T
F
T
Site 37
S472
T
R
R
H
N
K
S
S
S
A
F
T
F
T
C
Site 38
S473
R
R
H
N
K
S
S
S
A
F
T
F
T
C
N
Site 39
T476
N
K
S
S
S
A
F
T
F
T
C
N
K
F
F
Site 40
T478
S
S
S
A
F
T
F
T
C
N
K
F
F
R
R
Site 41
S537
Q
K
A
K
V
I
Y
S
Q
E
L
K
T
F
A
Site 42
T542
I
Y
S
Q
E
L
K
T
F
A
I
K
P
E
V
Site 43
S569
L
L
G
H
G
G
K
S
Q
N
S
L
T
S
L
Site 44
S572
H
G
G
K
S
Q
N
S
L
T
S
L
P
L
E
Site 45
T574
G
K
S
Q
N
S
L
T
S
L
P
L
E
I
L
Site 46
S575
K
S
Q
N
S
L
T
S
L
P
L
E
I
L
K
Site 47
Y626
L
Q
W
K
K
K
R
Y
S
H
G
G
T
S
W
Site 48
T631
K
R
Y
S
H
G
G
T
S
W
R
V
H
R
E
Site 49
S643
H
R
E
I
W
Q
F
S
S
L
F
S
K
I
K
Site 50
S644
R
E
I
W
Q
F
S
S
L
F
S
K
I
K
S
Site 51
S651
S
L
F
S
K
I
K
S
W
E
F
N
E
V
T
Site 52
S666
S
M
S
E
H
L
K
S
C
P
F
N
I
V
E
Site 53
T682
K
T
D
P
I
L
L
T
S
M
C
Q
P
R
E
Site 54
S683
T
D
P
I
L
L
T
S
M
C
Q
P
R
E
Q
Site 55
S694
P
R
E
Q
A
R
E
S
L
V
S
T
F
R
I
Site 56
S697
Q
A
R
E
S
L
V
S
T
F
R
I
R
P
R
Site 57
T698
A
R
E
S
L
V
S
T
F
R
I
R
P
R
G
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation