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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
ubiquilin 2
Full Name:
Ubiquilin-2
Alias:
Chap1; CHAP1/DSK2; DSK2; HRIHFB2157; LIC-2; N4BP4; NEDD4 binding protein 4; PLIC2; PLIC-2; Protein linking IAP with cytoskeleton-2; RIHFB2157; Ubiquilin 2; Ubiquitin-like product Chap1/Dsk2; UBQL2; UBQLN2
Type:
Ubiquitin conjugating system
Mass (Da):
65696
Number AA:
624
UniProt ID:
Q9UHD9
International Prot ID:
IPI00409659
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005737
GO:0005634
GO:0005886
Uniprot
OncoNet
Molecular Function:
GO:0005488
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S8
M
A
E
N
G
E
S
S
G
P
P
R
P
S
R
Site 2
S14
S
S
G
P
P
R
P
S
R
G
P
A
A
A
Q
Site 3
T39
I
I
K
V
T
V
K
T
P
K
E
K
E
E
F
Site 4
S62
Q
Q
F
K
E
A
I
S
K
R
F
K
S
Q
T
Site 5
S67
A
I
S
K
R
F
K
S
Q
T
D
Q
L
V
L
Site 6
T69
S
K
R
F
K
S
Q
T
D
Q
L
V
L
I
F
Site 7
T86
K
I
L
K
D
Q
D
T
L
I
Q
H
G
I
H
Site 8
S104
T
V
H
L
V
I
K
S
Q
N
R
P
Q
G
Q
Site 9
S112
Q
N
R
P
Q
G
Q
S
T
Q
P
S
N
A
A
Site 10
S116
Q
G
Q
S
T
Q
P
S
N
A
A
G
T
N
T
Site 11
T123
S
N
A
A
G
T
N
T
T
S
A
S
T
P
R
Site 12
S125
A
A
G
T
N
T
T
S
A
S
T
P
R
S
N
Site 13
S127
G
T
N
T
T
S
A
S
T
P
R
S
N
S
T
Site 14
T128
T
N
T
T
S
A
S
T
P
R
S
N
S
T
P
Site 15
S131
T
S
A
S
T
P
R
S
N
S
T
P
I
S
T
Site 16
S133
A
S
T
P
R
S
N
S
T
P
I
S
T
N
S
Site 17
T134
S
T
P
R
S
N
S
T
P
I
S
T
N
S
N
Site 18
S137
R
S
N
S
T
P
I
S
T
N
S
N
P
F
G
Site 19
S140
S
T
P
I
S
T
N
S
N
P
F
G
L
G
S
Site 20
S161
L
S
S
L
G
L
S
S
T
N
F
S
E
L
Q
Site 21
T162
S
S
L
G
L
S
S
T
N
F
S
E
L
Q
S
Site 22
S165
G
L
S
S
T
N
F
S
E
L
Q
S
Q
M
Q
Site 23
S169
T
N
F
S
E
L
Q
S
Q
M
Q
Q
Q
L
M
Site 24
S196
P
F
V
Q
S
M
L
S
N
P
D
L
M
R
Q
Site 25
S222
I
Q
R
N
P
E
I
S
H
L
L
N
N
P
D
Site 26
T234
N
P
D
I
M
R
Q
T
L
E
I
A
R
N
P
Site 27
S256
R
N
Q
D
L
A
L
S
N
L
E
S
I
P
G
Site 28
S260
L
A
L
S
N
L
E
S
I
P
G
G
Y
N
A
Site 29
Y265
L
E
S
I
P
G
G
Y
N
A
L
R
R
M
Y
Site 30
Y272
Y
N
A
L
R
R
M
Y
T
D
I
Q
E
P
M
Site 31
T273
N
A
L
R
R
M
Y
T
D
I
Q
E
P
M
L
Site 32
S294
F
G
G
N
P
F
A
S
V
G
S
S
S
S
S
Site 33
S297
N
P
F
A
S
V
G
S
S
S
S
S
G
E
G
Site 34
S298
P
F
A
S
V
G
S
S
S
S
S
G
E
G
T
Site 35
S299
F
A
S
V
G
S
S
S
S
S
G
E
G
T
Q
Site 36
S301
S
V
G
S
S
S
S
S
G
E
G
T
Q
P
S
Site 37
T305
S
S
S
S
G
E
G
T
Q
P
S
R
T
E
N
Site 38
S308
S
G
E
G
T
Q
P
S
R
T
E
N
R
D
P
Site 39
T310
E
G
T
Q
P
S
R
T
E
N
R
D
P
L
P
Site 40
T326
P
W
A
P
P
P
A
T
Q
S
S
A
T
T
S
Site 41
S329
P
P
P
A
T
Q
S
S
A
T
T
S
T
T
T
Site 42
T332
A
T
Q
S
S
A
T
T
S
T
T
T
S
T
G
Site 43
S333
T
Q
S
S
A
T
T
S
T
T
T
S
T
G
S
Site 44
T335
S
S
A
T
T
S
T
T
T
S
T
G
S
G
S
Site 45
T336
S
A
T
T
S
T
T
T
S
T
G
S
G
S
G
Site 46
S337
A
T
T
S
T
T
T
S
T
G
S
G
S
G
N
Site 47
T338
T
T
S
T
T
T
S
T
G
S
G
S
G
N
S
Site 48
S340
S
T
T
T
S
T
G
S
G
S
G
N
S
S
S
Site 49
S342
T
T
S
T
G
S
G
S
G
N
S
S
S
N
A
Site 50
S345
T
G
S
G
S
G
N
S
S
S
N
A
T
G
N
Site 51
S346
G
S
G
S
G
N
S
S
S
N
A
T
G
N
T
Site 52
S347
S
G
S
G
N
S
S
S
N
A
T
G
N
T
V
Site 53
T353
S
S
N
A
T
G
N
T
V
A
A
A
N
Y
V
Site 54
T377
Q
S
L
L
Q
Q
I
T
E
N
P
Q
L
I
Q
Site 55
Y391
Q
N
M
L
S
A
P
Y
M
R
S
M
M
Q
S
Site 56
S394
L
S
A
P
Y
M
R
S
M
M
Q
S
L
S
Q
Site 57
S398
Y
M
R
S
M
M
Q
S
L
S
Q
N
P
D
L
Site 58
S400
R
S
M
M
Q
S
L
S
Q
N
P
D
L
A
A
Site 59
T417
M
L
N
S
P
L
F
T
A
N
P
Q
L
Q
E
Site 60
T442
Q
Q
M
Q
N
P
D
T
L
S
A
M
S
N
P
Site 61
S444
M
Q
N
P
D
T
L
S
A
M
S
N
P
R
A
Site 62
S527
G
P
A
A
P
P
G
S
T
G
S
G
G
P
T
Site 63
S530
A
P
P
G
S
T
G
S
G
G
P
T
G
P
T
Site 64
T534
S
T
G
S
G
G
P
T
G
P
T
V
S
S
A
Site 65
T537
S
G
G
P
T
G
P
T
V
S
S
A
A
P
S
Site 66
S539
G
P
T
G
P
T
V
S
S
A
A
P
S
E
T
Site 67
S540
P
T
G
P
T
V
S
S
A
A
P
S
E
T
T
Site 68
S544
T
V
S
S
A
A
P
S
E
T
T
S
P
T
S
Site 69
T546
S
S
A
A
P
S
E
T
T
S
P
T
S
E
S
Site 70
S548
A
A
P
S
E
T
T
S
P
T
S
E
S
G
P
Site 71
T550
P
S
E
T
T
S
P
T
S
E
S
G
P
N
Q
Site 72
S551
S
E
T
T
S
P
T
S
E
S
G
P
N
Q
Q
Site 73
S621
A
I
E
R
L
L
G
S
Q
P
S
_
_
_
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation