KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
DrugProNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
Home
|
Kinexus
|
Contact
|
Credits
Protein Info
Short Name:
STEAP1
Full Name:
Metalloreductase STEAP1
Alias:
PRSS24; six transmembrane epithelial antigen of prostate 1; six transmembrane epithelial antigen of the prostate; six transmembrane epithelial antigen of the prostate 1; STEA1; STEAP
Type:
Adhesion; Oxidoreductase; EC 1.16.1.-; Transporter
Mass (Da):
39851
Number AA:
339
UniProt ID:
Q9UHE8
International Prot ID:
IPI00005846
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005911
GO:0005768
GO:0005887
Uniprot
OncoNet
Molecular Function:
GO:0050660
GO:0015267
GO:0005507
PhosphoSite+
KinaseNET
Biological Process:
GO:0022900
GO:0006826
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T8
M
E
S
R
K
D
I
T
N
Q
E
E
L
W
K
Site 2
Y27
R
N
L
E
E
D
D
Y
L
H
K
D
T
G
E
Site 3
T32
D
D
Y
L
H
K
D
T
G
E
T
S
M
L
K
Site 4
S59
A
D
E
F
D
C
P
S
E
L
Q
H
T
Q
E
Site 5
T64
C
P
S
E
L
Q
H
T
Q
E
L
F
P
Q
W
Site 6
Y147
Q
L
H
N
G
T
K
Y
K
K
F
P
H
W
L
Site 7
T160
W
L
D
K
W
M
L
T
R
K
Q
F
G
L
L
Site 8
Y178
F
A
V
L
H
A
I
Y
S
L
S
Y
P
M
R
Site 9
S181
L
H
A
I
Y
S
L
S
Y
P
M
R
R
S
Y
Site 10
Y182
H
A
I
Y
S
L
S
Y
P
M
R
R
S
Y
R
Site 11
S187
L
S
Y
P
M
R
R
S
Y
R
Y
K
L
L
N
Site 12
Y188
S
Y
P
M
R
R
S
Y
R
Y
K
L
L
N
W
Site 13
Y190
P
M
R
R
S
Y
R
Y
K
L
L
N
W
A
Y
Site 14
Y197
Y
K
L
L
N
W
A
Y
Q
Q
V
Q
Q
N
K
Site 15
S242
V
T
S
I
P
S
V
S
D
S
L
T
W
R
E
Site 16
S244
S
I
P
S
V
S
D
S
L
T
W
R
E
F
H
Site 17
T246
P
S
V
S
D
S
L
T
W
R
E
F
H
Y
I
Site 18
Y252
L
T
W
R
E
F
H
Y
I
Q
S
K
L
G
I
Site 19
S255
R
E
F
H
Y
I
Q
S
K
L
G
I
V
S
L
Site 20
T333
D
V
T
K
I
N
K
T
E
I
C
S
Q
L
_
Site 21
S337
I
N
K
T
E
I
C
S
Q
L
_
_
_
_
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation