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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
SLC7A8
Full Name:
Solute carrier family 7 member 8
Alias:
Hlat2; Integral membrane E16H; Large neutral amino acids transporter small 2; LAT2; LPI-PC1; L-type amino acid transporter 2; Solute carrier family 7 (cationic amino acid transporter, y+ system) member 8; Solute carrier family 7 (cationic amino acid transporter, y+ system), member 8
Type:
Transporter
Mass (Da):
58382
Number AA:
535
UniProt ID:
Q9UHI5
International Prot ID:
IPI00296114
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005737
GO:0005887
Uniprot
OncoNet
Molecular Function:
GO:0015175
GO:0015101
GO:0042605
PhosphoSite+
KinaseNET
Biological Process:
GO:0006520
GO:0055065
GO:0015804
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T11
G
A
R
H
R
N
N
T
E
K
K
H
P
G
G
Site 2
S21
K
H
P
G
G
G
E
S
D
A
S
P
E
A
G
Site 3
S24
G
G
G
E
S
D
A
S
P
E
A
G
S
G
G
Site 4
T99
C
Y
A
E
L
G
V
T
I
P
K
S
G
G
D
Site 5
S103
L
G
V
T
I
P
K
S
G
G
D
Y
S
Y
V
Site 6
Y107
I
P
K
S
G
G
D
Y
S
Y
V
K
D
I
F
Site 7
S108
P
K
S
G
G
D
Y
S
Y
V
K
D
I
F
G
Site 8
Y109
K
S
G
G
D
Y
S
Y
V
K
D
I
F
G
G
Site 9
Y214
V
Q
I
C
K
G
E
Y
F
W
L
E
P
K
N
Site 10
Y253
G
G
W
N
F
L
N
Y
V
T
E
E
L
V
D
Site 11
Y262
T
E
E
L
V
D
P
Y
K
N
L
P
R
A
I
Site 12
S477
Q
H
K
P
K
C
F
S
D
F
I
E
L
L
T
Site 13
Y495
Q
K
M
C
V
V
V
Y
P
E
V
E
R
G
S
Site 14
S502
Y
P
E
V
E
R
G
S
G
T
E
E
A
N
E
Site 15
Y519
E
E
Q
Q
Q
P
M
Y
Q
P
T
P
T
K
D
Site 16
T522
Q
Q
P
M
Y
Q
P
T
P
T
K
D
K
D
V
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation