PhosphoNET

           
Protein Info 
   
Short Name:  SLC7A8
Full Name:  Solute carrier family 7 member 8
Alias:  Hlat2; Integral membrane E16H; Large neutral amino acids transporter small 2; LAT2; LPI-PC1; L-type amino acid transporter 2; Solute carrier family 7 (cationic amino acid transporter, y+ system) member 8; Solute carrier family 7 (cationic amino acid transporter, y+ system), member 8
Type:  Transporter
Mass (Da):  58382
Number AA:  535
UniProt ID:  Q9UHI5
International Prot ID:  IPI00296114
Sequence:  Retrieve full protein sequence
   
GO Terms  External Links Internal Links  
   
Cellular Component:  GO:0005737  GO:0005887   Uniprot OncoNet
Molecular Function:  GO:0015175  GO:0015101  GO:0042605 PhosphoSite+ KinaseNET
Biological Process:  GO:0006520  GO:0055065  GO:0015804 Phosida TranscriptoNet
    STRING Kinexus Products
   
Info Box  A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites 
-7-6-5-4-3-2-101234567Expt. conf.EffectKinasePPaseKinexus ProductsRef.Evol.Kinase Pred.P-site Match
Site 1T11GARHRNNTEKKHPGG
Site 2S21KHPGGGESDASPEAG
Site 3S24GGGESDASPEAGSGG
Site 4T99CYAELGVTIPKSGGD
Site 5S103LGVTIPKSGGDYSYV
Site 6Y107IPKSGGDYSYVKDIF
Site 7S108PKSGGDYSYVKDIFG
Site 8Y109KSGGDYSYVKDIFGG
Site 9Y214VQICKGEYFWLEPKN
Site 10Y253GGWNFLNYVTEELVD
Site 11Y262TEELVDPYKNLPRAI
Site 12S477QHKPKCFSDFIELLT
Site 13Y495QKMCVVVYPEVERGS
Site 14S502YPEVERGSGTEEANE
Site 15Y519EEQQQPMYQPTPTKD
Site 16T522QQPMYQPTPTKDKDV
 
Legend 
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available  
Products available
 


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