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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
DDX20
Full Name:
Probable ATP-dependent RNA helicase DDX20
Alias:
Component of gems 3; DEAD (Asp-Glu-Ala-Asp) box polypeptide 20; DEAD box protein 20; DEAD box protein DP 103; DEAD- box protein DP 103; DEAD-box protein 20; DP103; GEMIN3; Gemin-3; Probable ATP-dependent RNA helicase DDX20; Regulator of steroidogenic factor-1; ROSF-1
Type:
Helicase; Nuclear receptor co-regulator; EC 3.6.1.-
Mass (Da):
92241
Number AA:
824
UniProt ID:
Q9UHI6
International Prot ID:
IPI00005904
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0015030
GO:0005856
GO:0005829
Uniprot
OncoNet
Molecular Function:
GO:0005524
GO:0004004
GO:0003677
PhosphoSite+
KinaseNET
Biological Process:
GO:0000244
GO:0043065
GO:0000387
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T33
Q
V
P
A
P
E
P
T
P
G
P
V
R
I
L
Site 2
T42
G
P
V
R
I
L
R
T
A
Q
D
L
S
S
P
Site 3
S47
L
R
T
A
Q
D
L
S
S
P
R
T
R
T
G
Site 4
S48
R
T
A
Q
D
L
S
S
P
R
T
R
T
G
D
Site 5
T51
Q
D
L
S
S
P
R
T
R
T
G
D
V
L
L
Site 6
T53
L
S
S
P
R
T
R
T
G
D
V
L
L
A
E
Site 7
S86
A
A
G
F
E
R
P
S
P
V
Q
L
K
A
I
Site 8
T169
C
H
V
F
I
G
G
T
P
L
S
Q
D
K
T
Site 9
S172
F
I
G
G
T
P
L
S
Q
D
K
T
R
L
K
Site 10
T176
T
P
L
S
Q
D
K
T
R
L
K
K
C
H
I
Site 11
S187
K
C
H
I
A
V
G
S
P
G
R
I
K
Q
L
Site 12
Y199
K
Q
L
I
E
L
D
Y
L
N
P
G
S
I
R
Site 13
S221
D
K
L
L
E
E
G
S
F
Q
E
Q
I
N
W
Site 14
S231
E
Q
I
N
W
I
Y
S
S
L
P
A
S
K
Q
Site 15
Y257
L
A
N
A
L
T
K
Y
M
R
D
P
T
F
V
Site 16
T262
T
K
Y
M
R
D
P
T
F
V
R
L
N
S
S
Site 17
S268
P
T
F
V
R
L
N
S
S
D
P
S
L
I
G
Site 18
S272
R
L
N
S
S
D
P
S
L
I
G
L
K
Q
Y
Site 19
Y279
S
L
I
G
L
K
Q
Y
Y
K
V
V
N
S
Y
Site 20
Y280
L
I
G
L
K
Q
Y
Y
K
V
V
N
S
Y
P
Site 21
S305
Q
H
L
Q
E
L
F
S
R
I
P
F
N
Q
A
Site 22
S320
L
V
F
S
N
L
H
S
R
A
Q
H
L
A
D
Site 23
S330
Q
H
L
A
D
I
L
S
S
K
G
F
P
A
E
Site 24
Y393
V
P
L
D
W
E
T
Y
M
H
R
I
G
R
A
Site 25
Y412
T
L
G
L
T
V
T
Y
C
C
R
G
E
E
E
Site 26
T461
E
V
K
A
A
V
H
T
Y
G
I
A
S
V
P
Site 27
Y462
V
K
A
A
V
H
T
Y
G
I
A
S
V
P
N
Site 28
S466
V
H
T
Y
G
I
A
S
V
P
N
Q
P
L
K
Site 29
S495
A
H
G
D
H
M
A
S
S
R
N
N
S
V
S
Site 30
S496
H
G
D
H
M
A
S
S
R
N
N
S
V
S
G
Site 31
S500
M
A
S
S
R
N
N
S
V
S
G
L
S
V
K
Site 32
S502
S
S
R
N
N
S
V
S
G
L
S
V
K
S
K
Site 33
S505
N
N
S
V
S
G
L
S
V
K
S
K
N
N
T
Site 34
S508
V
S
G
L
S
V
K
S
K
N
N
T
K
Q
K
Site 35
T512
S
V
K
S
K
N
N
T
K
Q
K
L
P
V
K
Site 36
S520
K
Q
K
L
P
V
K
S
H
S
E
C
G
I
I
Site 37
S522
K
L
P
V
K
S
H
S
E
C
G
I
I
E
K
Site 38
S532
G
I
I
E
K
A
T
S
P
K
E
L
G
C
D
Site 39
S542
E
L
G
C
D
R
Q
S
E
E
Q
M
K
N
S
Site 40
S549
S
E
E
Q
M
K
N
S
V
Q
T
P
V
E
N
Site 41
T552
Q
M
K
N
S
V
Q
T
P
V
E
N
S
T
N
Site 42
S557
V
Q
T
P
V
E
N
S
T
N
S
Q
H
Q
V
Site 43
S560
P
V
E
N
S
T
N
S
Q
H
Q
V
K
E
A
Site 44
Y587
S
F
K
I
H
Q
P
Y
T
L
T
F
A
E
L
Site 45
T590
I
H
Q
P
Y
T
L
T
F
A
E
L
V
E
D
Site 46
Y598
F
A
E
L
V
E
D
Y
E
H
Y
I
K
E
G
Site 47
Y601
L
V
E
D
Y
E
H
Y
I
K
E
G
L
E
K
Site 48
Y616
P
V
E
I
I
R
H
Y
T
G
P
G
D
Q
T
Site 49
T617
V
E
I
I
R
H
Y
T
G
P
G
D
Q
T
V
Site 50
T623
Y
T
G
P
G
D
Q
T
V
N
P
Q
N
G
F
Site 51
S645
Q
R
V
P
V
L
A
S
S
S
Q
S
G
D
S
Site 52
S646
R
V
P
V
L
A
S
S
S
Q
S
G
D
S
E
Site 53
S647
V
P
V
L
A
S
S
S
Q
S
G
D
S
E
S
Site 54
S649
V
L
A
S
S
S
Q
S
G
D
S
E
S
D
S
Site 55
S652
S
S
S
Q
S
G
D
S
E
S
D
S
D
S
Y
Site 56
S654
S
Q
S
G
D
S
E
S
D
S
D
S
Y
S
S
Site 57
S656
S
G
D
S
E
S
D
S
D
S
Y
S
S
R
T
Site 58
S658
D
S
E
S
D
S
D
S
Y
S
S
R
T
S
S
Site 59
Y659
S
E
S
D
S
D
S
Y
S
S
R
T
S
S
Q
Site 60
S660
E
S
D
S
D
S
Y
S
S
R
T
S
S
Q
S
Site 61
S661
S
D
S
D
S
Y
S
S
R
T
S
S
Q
S
K
Site 62
T663
S
D
S
Y
S
S
R
T
S
S
Q
S
K
G
N
Site 63
S664
D
S
Y
S
S
R
T
S
S
Q
S
K
G
N
K
Site 64
S665
S
Y
S
S
R
T
S
S
Q
S
K
G
N
K
S
Site 65
S667
S
S
R
T
S
S
Q
S
K
G
N
K
S
Y
L
Site 66
S672
S
Q
S
K
G
N
K
S
Y
L
E
G
S
S
D
Site 67
Y673
Q
S
K
G
N
K
S
Y
L
E
G
S
S
D
N
Site 68
S677
N
K
S
Y
L
E
G
S
S
D
N
Q
L
K
D
Site 69
S678
K
S
Y
L
E
G
S
S
D
N
Q
L
K
D
S
Site 70
S685
S
D
N
Q
L
K
D
S
E
S
T
P
V
D
D
Site 71
S687
N
Q
L
K
D
S
E
S
T
P
V
D
D
R
I
Site 72
T688
Q
L
K
D
S
E
S
T
P
V
D
D
R
I
S
Site 73
S695
T
P
V
D
D
R
I
S
L
E
Q
P
P
N
G
Site 74
S703
L
E
Q
P
P
N
G
S
D
T
P
N
P
E
K
Site 75
T705
Q
P
P
N
G
S
D
T
P
N
P
E
K
Y
Q
Site 76
Y711
D
T
P
N
P
E
K
Y
Q
E
S
P
G
I
Q
Site 77
S714
N
P
E
K
Y
Q
E
S
P
G
I
Q
M
K
T
Site 78
T721
S
P
G
I
Q
M
K
T
R
L
K
E
G
A
S
Site 79
S728
T
R
L
K
E
G
A
S
Q
R
A
K
Q
S
R
Site 80
S734
A
S
Q
R
A
K
Q
S
R
R
N
L
P
R
R
Site 81
S742
R
R
N
L
P
R
R
S
S
F
R
L
Q
T
E
Site 82
S743
R
N
L
P
R
R
S
S
F
R
L
Q
T
E
A
Site 83
T748
R
S
S
F
R
L
Q
T
E
A
Q
E
D
D
W
Site 84
Y756
E
A
Q
E
D
D
W
Y
D
C
H
R
E
I
R
Site 85
S765
C
H
R
E
I
R
L
S
F
S
D
T
Y
Q
D
Site 86
S767
R
E
I
R
L
S
F
S
D
T
Y
Q
D
Y
E
Site 87
T769
I
R
L
S
F
S
D
T
Y
Q
D
Y
E
E
Y
Site 88
Y770
R
L
S
F
S
D
T
Y
Q
D
Y
E
E
Y
W
Site 89
Y773
F
S
D
T
Y
Q
D
Y
E
E
Y
W
R
A
Y
Site 90
Y776
T
Y
Q
D
Y
E
E
Y
W
R
A
Y
Y
R
A
Site 91
Y787
Y
Y
R
A
W
Q
E
Y
Y
A
A
A
S
H
S
Site 92
Y788
Y
R
A
W
Q
E
Y
Y
A
A
A
S
H
S
Y
Site 93
Y796
A
A
A
S
H
S
Y
Y
W
N
A
Q
R
H
P
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation