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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
NUFIP1
Full Name:
Nuclear fragile X mental retardation-interacting protein 1
Alias:
Nuclear FMRP-interacting protein 1; Nuclear fragile X mental retardation intercating protein 1; Nuclear fragile X mental retardation protein interacting protein 1; NUFIP; NUFP1
Type:
Intracellular, Presynaptic active zone, Nuclear matrix, Transcription elongation factor complex, Perichromatin fibrils, Nucleolus, Nucleus protein
Mass (Da):
56300
Number AA:
495
UniProt ID:
Q9UHK0
International Prot ID:
IPI00017630
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0022626
GO:0016363
GO:0005730
Uniprot
OncoNet
Molecular Function:
GO:0003677
GO:0003723
GO:0042802
PhosphoSite+
KinaseNET
Biological Process:
GO:0006396
GO:0000492
GO:0045944
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S6
_
_
M
A
E
P
T
S
D
F
E
T
P
I
G
Site 2
T10
E
P
T
S
D
F
E
T
P
I
G
W
H
A
S
Site 3
S17
T
P
I
G
W
H
A
S
P
E
L
T
P
T
L
Site 4
T21
W
H
A
S
P
E
L
T
P
T
L
G
P
L
S
Site 5
T23
A
S
P
E
L
T
P
T
L
G
P
L
S
D
T
Site 6
S28
T
P
T
L
G
P
L
S
D
T
A
P
P
R
D
Site 7
T30
T
L
G
P
L
S
D
T
A
P
P
R
D
S
W
Site 8
T51
P
P
P
P
P
P
L
T
S
S
L
P
A
A
G
Site 9
S52
P
P
P
P
P
L
T
S
S
L
P
A
A
G
S
Site 10
S53
P
P
P
P
L
T
S
S
L
P
A
A
G
S
K
Site 11
S59
S
S
L
P
A
A
G
S
K
P
S
S
E
S
Q
Site 12
S62
P
A
A
G
S
K
P
S
S
E
S
Q
P
P
M
Site 13
S63
A
A
G
S
K
P
S
S
E
S
Q
P
P
M
E
Site 14
S65
G
S
K
P
S
S
E
S
Q
P
P
M
E
A
Q
Site 15
S73
Q
P
P
M
E
A
Q
S
L
P
G
A
P
P
P
Site 16
S97
Q
P
P
F
D
A
Q
S
P
L
D
S
Q
P
Q
Site 17
S101
D
A
Q
S
P
L
D
S
Q
P
Q
P
S
G
Q
Site 18
S106
L
D
S
Q
P
Q
P
S
G
Q
P
W
N
F
H
Site 19
Y119
F
H
A
S
T
S
W
Y
W
R
Q
S
S
D
R
Site 20
S133
R
F
P
R
H
Q
K
S
F
N
P
A
V
K
N
Site 21
Y143
P
A
V
K
N
S
Y
Y
P
R
K
Y
D
A
K
Site 22
Y147
N
S
Y
Y
P
R
K
Y
D
A
K
F
T
D
F
Site 23
S155
D
A
K
F
T
D
F
S
L
P
P
S
R
K
Q
Site 24
S159
T
D
F
S
L
P
P
S
R
K
Q
K
K
K
K
Site 25
Y189
G
F
K
N
Q
E
K
Y
D
K
H
M
S
E
H
Site 26
S205
K
C
P
E
L
D
C
S
F
T
A
H
E
K
I
Site 27
T232
M
K
K
I
K
L
D
T
P
E
E
I
A
R
W
Site 28
Y247
R
E
E
R
R
K
N
Y
P
T
L
A
N
I
E
Site 29
T249
E
R
R
K
N
Y
P
T
L
A
N
I
E
R
K
Site 30
T271
E
K
R
G
A
V
L
T
T
T
Q
Y
G
K
M
Site 31
T273
R
G
A
V
L
T
T
T
Q
Y
G
K
M
K
G
Site 32
Y275
A
V
L
T
T
T
Q
Y
G
K
M
K
G
M
S
Site 33
S285
M
K
G
M
S
R
H
S
Q
M
A
K
I
R
S
Site 34
S292
S
Q
M
A
K
I
R
S
P
G
K
N
H
K
W
Site 35
T310
N
S
R
Q
R
A
V
T
G
S
G
S
H
L
C
Site 36
S312
R
Q
R
A
V
T
G
S
G
S
H
L
C
D
L
Site 37
S338
P
L
G
V
L
I
N
S
D
S
E
S
D
K
E
Site 38
S340
G
V
L
I
N
S
D
S
E
S
D
K
E
E
K
Site 39
S342
L
I
N
S
D
S
E
S
D
K
E
E
K
P
Q
Site 40
S351
K
E
E
K
P
Q
H
S
V
I
P
K
E
V
T
Site 41
T358
S
V
I
P
K
E
V
T
P
A
L
C
S
L
M
Site 42
S363
E
V
T
P
A
L
C
S
L
M
S
S
Y
G
S
Site 43
S366
P
A
L
C
S
L
M
S
S
Y
G
S
L
S
G
Site 44
S367
A
L
C
S
L
M
S
S
Y
G
S
L
S
G
S
Site 45
Y368
L
C
S
L
M
S
S
Y
G
S
L
S
G
S
E
Site 46
S370
S
L
M
S
S
Y
G
S
L
S
G
S
E
S
E
Site 47
S372
M
S
S
Y
G
S
L
S
G
S
E
S
E
P
E
Site 48
S374
S
Y
G
S
L
S
G
S
E
S
E
P
E
E
T
Site 49
S376
G
S
L
S
G
S
E
S
E
P
E
E
T
P
I
Site 50
T381
S
E
S
E
P
E
E
T
P
I
K
T
E
A
D
Site 51
S398
A
E
N
Q
V
L
D
S
S
A
P
K
S
P
S
Site 52
S399
E
N
Q
V
L
D
S
S
A
P
K
S
P
S
Q
Site 53
S403
L
D
S
S
A
P
K
S
P
S
Q
D
V
K
A
Site 54
S405
S
S
A
P
K
S
P
S
Q
D
V
K
A
T
V
Site 55
T411
P
S
Q
D
V
K
A
T
V
R
N
F
S
E
A
Site 56
S416
K
A
T
V
R
N
F
S
E
A
K
S
E
N
R
Site 57
S420
R
N
F
S
E
A
K
S
E
N
R
K
K
S
F
Site 58
S426
K
S
E
N
R
K
K
S
F
E
K
T
N
P
K
Site 59
T430
R
K
K
S
F
E
K
T
N
P
K
R
K
K
D
Site 60
Y438
N
P
K
R
K
K
D
Y
H
N
Y
Q
T
L
F
Site 61
Y441
R
K
K
D
Y
H
N
Y
Q
T
L
F
E
P
R
Site 62
T449
Q
T
L
F
E
P
R
T
H
H
P
Y
L
L
E
Site 63
Y453
E
P
R
T
H
H
P
Y
L
L
E
M
L
L
A
Site 64
Y476
V
I
L
Q
C
V
R
Y
I
I
K
K
D
F
F
Site 65
T487
K
D
F
F
G
L
D
T
N
S
A
K
S
K
D
Site 66
S489
F
F
G
L
D
T
N
S
A
K
S
K
D
V
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation