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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
DDX25
Full Name:
Alias:
DEAD box protein 25;Gonadotropin-regulated testicular RNA helicase
Type:
Mass (Da):
54692
Number AA:
483
UniProt ID:
Q9UHL0
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S15
G
D
A
G
A
A
E
S
E
R
L
N
S
H
F
Site 2
S20
A
E
S
E
R
L
N
S
H
F
S
N
L
S
Q
Site 3
S23
E
R
L
N
S
H
F
S
N
L
S
Q
P
R
K
Site 4
S26
N
S
H
F
S
N
L
S
Q
P
R
K
N
L
W
Site 5
S46
A
V
R
N
I
D
G
S
I
N
N
I
N
E
D
Site 6
S74
L
N
K
L
I
H
Q
S
L
V
E
S
S
H
R
Site 7
S78
I
H
Q
S
L
V
E
S
S
H
R
V
E
V
L
Site 8
S79
H
Q
S
L
V
E
S
S
H
R
V
E
V
L
Q
Site 9
S90
E
V
L
Q
K
D
P
S
S
P
L
Y
S
V
K
Site 10
S91
V
L
Q
K
D
P
S
S
P
L
Y
S
V
K
T
Site 11
Y94
K
D
P
S
S
P
L
Y
S
V
K
T
F
E
E
Site 12
S95
D
P
S
S
P
L
Y
S
V
K
T
F
E
E
L
Site 13
T98
S
P
L
Y
S
V
K
T
F
E
E
L
R
L
K
Site 14
Y113
E
E
L
L
K
G
I
Y
A
M
G
F
N
R
P
Site 15
S121
A
M
G
F
N
R
P
S
K
I
Q
E
M
A
L
Site 16
S143
P
Q
N
L
I
A
Q
S
Q
S
G
T
G
K
T
Site 17
T212
G
N
R
I
P
R
G
T
D
I
T
K
Q
I
I
Site 18
T255
E
A
D
V
M
I
D
T
Q
G
F
S
D
H
S
Site 19
S262
T
Q
G
F
S
D
H
S
I
R
I
Q
R
A
L
Site 20
T308
K
L
R
K
E
E
L
T
L
N
N
I
R
Q
Y
Site 21
Y315
T
L
N
N
I
R
Q
Y
Y
V
L
C
E
H
R
Site 22
Y316
L
N
N
I
R
Q
Y
Y
V
L
C
E
H
R
K
Site 23
Y326
C
E
H
R
K
D
K
Y
Q
A
L
C
N
I
Y
Site 24
T355
R
R
N
A
K
W
L
T
V
E
M
I
Q
D
G
Site 25
S366
I
Q
D
G
H
Q
V
S
L
L
S
G
E
L
T
Site 26
S369
G
H
Q
V
S
L
L
S
G
E
L
T
V
E
Q
Site 27
S379
L
T
V
E
Q
R
A
S
I
I
Q
R
F
R
D
Site 28
Y425
K
Q
G
E
E
P
D
Y
E
T
Y
L
H
R
I
Site 29
T427
G
E
E
P
D
Y
E
T
Y
L
H
R
I
G
R
Site 30
Y428
E
E
P
D
Y
E
T
Y
L
H
R
I
G
R
T
Site 31
S455
I
E
V
D
E
L
P
S
L
M
K
I
Q
D
H
Site 32
S465
K
I
Q
D
H
F
N
S
S
I
K
Q
L
N
A
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation