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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
DPP7
Full Name:
Alias:
Dipeptidyl aminopeptidase II;Dipeptidyl peptidase 7;Dipeptidyl peptidase II;Quiescent cell proline dipeptidase
Type:
Mass (Da):
54341
Number AA:
492
UniProt ID:
Q9UHL4
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T52
F
E
R
F
G
N
K
T
F
P
Q
R
F
L
V
Site 2
Y74
G
E
G
P
I
F
F
Y
T
G
N
E
G
D
V
Site 3
Y109
L
V
F
A
E
H
R
Y
Y
G
K
S
L
P
F
Site 4
Y110
V
F
A
E
H
R
Y
Y
G
K
S
L
P
F
G
Site 5
S113
E
H
R
Y
Y
G
K
S
L
P
F
G
A
Q
S
Site 6
T121
L
P
F
G
A
Q
S
T
Q
R
G
H
T
E
L
Site 7
T126
Q
S
T
Q
R
G
H
T
E
L
L
T
V
E
Q
Site 8
T130
R
G
H
T
E
L
L
T
V
E
Q
A
L
A
D
Site 9
Y163
A
I
A
F
G
G
S
Y
G
G
M
L
S
A
Y
Site 10
S168
G
S
Y
G
G
M
L
S
A
Y
L
R
M
K
Y
Site 11
Y170
Y
G
G
M
L
S
A
Y
L
R
M
K
Y
P
H
Site 12
S198
A
V
A
G
L
G
D
S
N
Q
F
F
R
D
V
Site 13
T206
N
Q
F
F
R
D
V
T
A
D
F
E
G
Q
S
Site 14
S213
T
A
D
F
E
G
Q
S
P
K
C
T
Q
G
V
Site 15
T217
E
G
Q
S
P
K
C
T
Q
G
V
R
E
A
F
Site 16
T238
F
L
Q
G
A
Y
D
T
V
R
W
E
F
G
T
Site 17
T245
T
V
R
W
E
F
G
T
C
Q
P
L
S
D
E
Site 18
S250
F
G
T
C
Q
P
L
S
D
E
K
D
L
T
Q
Site 19
T256
L
S
D
E
K
D
L
T
Q
L
F
M
F
A
R
Site 20
Y276
L
A
M
M
D
Y
P
Y
P
T
D
F
L
G
P
Site 21
S298
V
G
C
D
R
L
L
S
E
A
Q
R
I
T
G
Site 22
Y314
R
A
L
A
G
L
V
Y
N
A
S
G
S
E
H
Site 23
S317
A
G
L
V
Y
N
A
S
G
S
E
H
C
Y
D
Site 24
Y323
A
S
G
S
E
H
C
Y
D
I
Y
R
L
Y
H
Site 25
Y326
S
E
H
C
Y
D
I
Y
R
L
Y
H
S
C
A
Site 26
Y329
C
Y
D
I
Y
R
L
Y
H
S
C
A
D
P
T
Site 27
T336
Y
H
S
C
A
D
P
T
G
C
G
T
G
P
D
Site 28
Y349
P
D
A
R
A
W
D
Y
Q
A
C
T
E
I
N
Site 29
T365
T
F
A
S
N
N
V
T
D
M
F
P
D
L
P
Site 30
T374
M
F
P
D
L
P
F
T
D
E
L
R
Q
R
Y
Site 31
Y381
T
D
E
L
R
Q
R
Y
C
L
D
T
W
G
V
Site 32
T397
P
R
P
D
W
L
L
T
S
F
W
G
G
D
L
Site 33
S398
R
P
D
W
L
L
T
S
F
W
G
G
D
L
R
Site 34
S408
G
G
D
L
R
A
A
S
N
I
I
F
S
N
G
Site 35
S450
H
H
L
D
L
R
A
S
H
P
E
D
P
A
S
Site 36
S457
S
H
P
E
D
P
A
S
V
V
E
A
R
K
L
Site 37
T467
E
A
R
K
L
E
A
T
I
I
G
E
W
V
K
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation