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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
POLG2
Full Name:
Alias:
DNA polymerase gamma accessory 55 kDa subunit;Mitochondrial DNA polymerase accessory subunit;MtPolB;PolG-beta
Type:
Mass (Da):
54911
Number AA:
485
UniProt ID:
Q9UHN1
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T34
A
G
Q
P
E
L
L
T
E
R
S
S
P
K
G
Site 2
S37
P
E
L
L
T
E
R
S
S
P
K
G
G
H
V
Site 3
S38
E
L
L
T
E
R
S
S
P
K
G
G
H
V
K
Site 4
S46
P
K
G
G
H
V
K
S
H
A
E
L
E
G
N
Site 5
S62
E
H
P
E
A
P
G
S
G
E
G
S
E
A
L
Site 6
S80
C
Q
R
R
H
F
L
S
G
S
K
Q
Q
L
S
Site 7
S82
R
R
H
F
L
S
G
S
K
Q
Q
L
S
R
D
Site 8
S87
S
G
S
K
Q
Q
L
S
R
D
S
L
L
S
G
Site 9
S90
K
Q
Q
L
S
R
D
S
L
L
S
G
C
H
P
Site 10
S93
L
S
R
D
S
L
L
S
G
C
H
P
G
F
G
Site 11
S149
D
S
A
F
R
L
V
S
A
E
T
L
R
E
I
Site 12
T152
F
R
L
V
S
A
E
T
L
R
E
I
L
Q
D
Site 13
S230
Q
I
R
N
G
V
K
S
I
G
E
K
T
E
A
Site 14
S238
I
G
E
K
T
E
A
S
L
V
W
F
T
P
P
Site 15
T243
E
A
S
L
V
W
F
T
P
P
R
T
S
N
Q
Site 16
S269
W
W
R
K
F
A
M
S
P
S
N
F
S
S
S
Site 17
S271
R
K
F
A
M
S
P
S
N
F
S
S
S
D
C
Site 18
S275
M
S
P
S
N
F
S
S
S
D
C
Q
D
E
E
Site 19
S276
S
P
S
N
F
S
S
S
D
C
Q
D
E
E
G
Site 20
Y290
G
R
K
G
N
K
L
Y
Y
N
F
P
W
G
K
Site 21
Y291
R
K
G
N
K
L
Y
Y
N
F
P
W
G
K
E
Site 22
Y315
D
H
E
L
L
H
M
Y
P
G
N
V
S
K
L
Site 23
Y351
R
G
M
L
A
Y
L
Y
D
S
F
Q
L
T
E
Site 24
S353
M
L
A
Y
L
Y
D
S
F
Q
L
T
E
N
S
Site 25
T357
L
Y
D
S
F
Q
L
T
E
N
S
F
T
R
K
Site 26
S360
S
F
Q
L
T
E
N
S
F
T
R
K
K
N
L
Site 27
T362
Q
L
T
E
N
S
F
T
R
K
K
N
L
H
R
Site 28
T392
L
D
V
G
R
G
P
T
L
E
L
R
Q
V
C
Site 29
S412
E
L
L
E
N
G
I
S
V
W
P
G
Y
L
E
Site 30
Y417
G
I
S
V
W
P
G
Y
L
E
T
M
Q
S
S
Site 31
T420
V
W
P
G
Y
L
E
T
M
Q
S
S
L
E
Q
Site 32
S423
G
Y
L
E
T
M
Q
S
S
L
E
Q
L
Y
S
Site 33
S424
Y
L
E
T
M
Q
S
S
L
E
Q
L
Y
S
K
Site 34
S430
S
S
L
E
Q
L
Y
S
K
Y
D
E
M
S
I
Site 35
Y432
L
E
Q
L
Y
S
K
Y
D
E
M
S
I
L
F
Site 36
S457
N
G
L
I
H
L
R
S
R
D
T
T
M
K
E
Site 37
T460
I
H
L
R
S
R
D
T
T
M
K
E
M
M
H
Site 38
T461
H
L
R
S
R
D
T
T
M
K
E
M
M
H
I
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation