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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
NARF
Full Name:
Nuclear prelamin A recognition factor
Alias:
IOP2; Prenyl-dependent prelamin A binding protein
Type:
Lamin filament, Nuclear lumen, Nucleus protein
Mass (Da):
51156
Number AA:
456
UniProt ID:
Q9UHQ1
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005638
Uniprot
OncoNet
Molecular Function:
GO:0005521
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T17
E
C
S
K
K
T
K
T
D
D
Q
E
N
V
S
Site 2
S29
N
V
S
A
D
A
P
S
P
A
Q
E
N
G
E
Site 3
S69
A
E
E
G
V
Q
L
S
Q
Q
N
A
K
D
F
Site 4
S89
L
N
K
K
C
D
T
S
K
H
K
V
L
V
V
Site 5
S113
F
A
A
K
F
N
L
S
V
T
D
A
S
R
R
Site 6
S143
T
T
I
A
A
D
F
S
I
L
E
S
Q
K
E
Site 7
S147
A
D
F
S
I
L
E
S
Q
K
E
F
V
R
R
Site 8
Y155
Q
K
E
F
V
R
R
Y
R
Q
H
S
E
E
E
Site 9
S159
V
R
R
Y
R
Q
H
S
E
E
E
R
T
L
P
Site 10
T164
Q
H
S
E
E
E
R
T
L
P
M
L
T
S
A
Site 11
Y178
A
C
P
G
W
V
R
Y
A
E
R
V
L
G
R
Site 12
S196
A
H
L
C
T
A
K
S
P
Q
Q
V
M
G
S
Site 13
S203
S
P
Q
Q
V
M
G
S
L
V
K
D
Y
F
A
Site 14
Y208
M
G
S
L
V
K
D
Y
F
A
R
Q
Q
N
L
Site 15
S216
F
A
R
Q
Q
N
L
S
P
E
K
I
F
H
V
Site 16
Y229
H
V
I
V
A
P
C
Y
D
K
K
L
E
A
L
Site 17
S239
K
L
E
A
L
Q
E
S
L
P
P
A
L
H
G
Site 18
S269
I
M
E
Q
G
D
L
S
V
R
D
A
A
V
D
Site 19
T277
V
R
D
A
A
V
D
T
L
F
G
D
L
K
E
Site 20
T288
D
L
K
E
D
K
V
T
R
H
D
G
A
S
S
Site 21
S294
V
T
R
H
D
G
A
S
S
D
G
H
L
A
H
Site 22
Y320
E
D
V
E
E
V
T
Y
R
A
L
R
N
K
D
Site 23
T387
N
G
R
G
Q
A
Q
T
P
D
G
H
A
D
K
Site 24
Y404
L
R
Q
M
E
G
I
Y
A
D
I
P
V
R
R
Site 25
S414
I
P
V
R
R
P
E
S
S
A
H
V
Q
E
L
Site 26
S415
P
V
R
R
P
E
S
S
A
H
V
Q
E
L
Y
Site 27
Y422
S
A
H
V
Q
E
L
Y
Q
E
W
L
E
G
I
Site 28
S431
E
W
L
E
G
I
N
S
P
K
A
R
E
V
L
Site 29
T440
K
A
R
E
V
L
H
T
T
Y
Q
S
Q
E
R
Site 30
Y442
R
E
V
L
H
T
T
Y
Q
S
Q
E
R
G
T
Site 31
S444
V
L
H
T
T
Y
Q
S
Q
E
R
G
T
H
S
Site 32
T449
Y
Q
S
Q
E
R
G
T
H
S
L
D
I
K
W
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation