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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
CYB5R1
Full Name:
NADH-cytochrome b5 reductase 1
Alias:
B5R.1; Cytochrome b5 reductase 1; Cytochrome b5 reductase 1 (B5R.1); EC 1.6.2.2; H:quinone oxidoreductase type 3 polypeptide A2; Humb5R2; NAD; NAD(P)H:quinone oxidoreductase type 3 polypeptide A2; NAD(P)H:quinone oxidoreductase type 3, polypeptide A2; NB5R1; NQO3A2
Type:
Membrane, Cytoplasm, Nucleolus, Integral membrane protein
Mass (Da):
34095
Number AA:
305
UniProt ID:
Q9UHQ9
International Prot ID:
IPI00470674
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005730
GO:0005737
GO:0016020
Uniprot
OncoNet
Molecular Function:
GO:0003824
GO:0004128
GO:0009055
PhosphoSite+
KinaseNET
Biological Process:
GO:0006066
GO:0006629
GO:0006694
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
Y28
L
G
L
A
V
G
S
Y
L
V
R
R
S
R
R
Site 2
S33
G
S
Y
L
V
R
R
S
R
R
P
Q
V
T
L
Site 3
T39
R
S
R
R
P
Q
V
T
L
L
D
P
N
E
K
Site 4
Y47
L
L
D
P
N
E
K
Y
L
L
R
L
L
D
K
Site 5
T55
L
L
R
L
L
D
K
T
T
V
S
H
N
T
K
Site 6
T56
L
R
L
L
D
K
T
T
V
S
H
N
T
K
R
Site 7
Y84
L
P
V
G
K
H
I
Y
L
S
T
R
I
D
G
Site 8
S86
V
G
K
H
I
Y
L
S
T
R
I
D
G
S
L
Site 9
S92
L
S
T
R
I
D
G
S
L
V
I
R
P
Y
T
Site 10
Y98
G
S
L
V
I
R
P
Y
T
P
V
T
S
D
E
Site 11
T99
S
L
V
I
R
P
Y
T
P
V
T
S
D
E
D
Site 12
S103
R
P
Y
T
P
V
T
S
D
E
D
Q
G
Y
V
Site 13
Y109
T
S
D
E
D
Q
G
Y
V
D
L
V
I
K
V
Site 14
S132
F
P
E
G
G
K
M
S
Q
Y
L
D
S
L
K
Site 15
Y134
E
G
G
K
M
S
Q
Y
L
D
S
L
K
V
G
Site 16
S137
K
M
S
Q
Y
L
D
S
L
K
V
G
D
V
V
Site 17
T154
R
G
P
S
G
L
L
T
Y
T
G
K
G
H
F
Site 18
Y155
G
P
S
G
L
L
T
Y
T
G
K
G
H
F
N
Site 19
S169
N
I
Q
P
N
K
K
S
P
P
E
P
R
V
A
Site 20
T186
L
G
M
I
A
G
G
T
G
I
T
P
M
L
Q
Site 21
T189
I
A
G
G
T
G
I
T
P
M
L
Q
L
I
R
Site 22
T206
L
K
V
P
E
D
P
T
Q
C
F
L
L
F
A
Site 23
Y233
L
E
E
L
Q
A
R
Y
P
N
R
F
K
L
W
Site 24
T242
N
R
F
K
L
W
F
T
L
D
H
P
P
K
D
Site 25
Y252
H
P
P
K
D
W
A
Y
S
K
G
F
V
T
A
Site 26
T258
A
Y
S
K
G
F
V
T
A
D
M
I
R
E
H
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation