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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
NRBP1
Full Name:
Nuclear receptor binding protein 1
Alias:
BCON3; DKFZp564D1878; FLJ11084; MADM; MUDPNP; NRBP; Nuclear receptor binding protein
Type:
Protein kinase, Ser/Thr (non-receptor); Other group; NRBP family
Mass (Da):
59845
Number AA:
535
UniProt ID:
Q9UHY1
International Prot ID:
IPI00893743
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005737
GO:0012505
GO:0016020
Uniprot
OncoNet
Molecular Function:
GO:0000166
GO:0003824
GO:0004672
PhosphoSite+
KinaseNET
Biological Process:
GO:0006464
GO:0006468
GO:0006793
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S2
_
_
_
_
_
_
M
S
E
G
E
S
Q
T
V
Site 2
S6
_
_
M
S
E
G
E
S
Q
T
V
L
S
S
G
Site 3
T8
S
Q
T
V
L
S
S
G
S
D
P
K
V
E
S
Site 4
S11
G
E
S
Q
T
V
L
S
S
G
S
D
P
K
V
Site 5
S12
E
S
Q
T
V
L
S
S
G
S
D
P
K
V
E
Site 6
S14
Q
T
V
L
S
S
G
S
D
P
K
V
E
S
S
Site 7
S20
G
S
D
P
K
V
E
S
S
S
S
A
P
G
L
Site 8
S21
S
D
P
K
V
E
S
S
S
S
A
P
G
L
T
Site 9
S22
D
P
K
V
E
S
S
S
S
A
P
G
L
T
S
Site 10
S23
P
K
V
E
S
S
S
S
A
P
G
L
T
S
V
Site 11
T28
S
S
S
A
P
G
L
T
S
V
S
P
P
V
T
Site 12
S29
S
S
A
P
G
L
T
S
V
S
P
P
V
T
S
Site 13
T35
T
S
V
S
P
P
V
T
S
T
T
S
A
A
S
Site 14
S36
S
V
S
P
P
V
T
S
T
T
S
A
A
S
P
Site 15
T38
S
P
P
V
T
S
T
T
S
A
A
S
P
E
E
Site 16
S42
T
S
T
T
S
A
A
S
P
E
E
E
E
E
S
Site 17
S49
S
P
E
E
E
E
E
S
E
D
E
S
E
I
L
Site 18
S53
E
E
E
S
E
D
E
S
E
I
L
E
E
S
P
Site 19
S59
E
S
E
I
L
E
E
S
P
C
G
R
W
Q
K
Site 20
Y83
V
P
G
I
D
S
A
Y
L
A
M
D
T
E
E
Site 21
Y107
Q
F
S
E
R
K
N
Y
K
L
Q
E
E
K
V
Site 22
Y152
R
V
I
F
I
T
E
Y
M
S
S
G
S
L
K
Site 23
S157
T
E
Y
M
S
S
G
S
L
K
Q
F
L
K
K
Site 24
T182
K
A
W
K
R
W
C
T
Q
I
L
S
A
L
S
Site 25
T225
I
G
S
V
A
P
D
T
I
N
N
H
V
K
T
Site 26
T232
T
I
N
N
H
V
K
T
C
R
E
E
Q
K
N
Site 27
Y282
Q
G
N
G
E
S
S
Y
V
P
Q
E
A
I
S
Site 28
T317
S
E
P
A
R
R
P
T
A
R
E
L
L
F
H
Site 29
T380
P
G
R
E
P
V
Q
T
L
Y
S
Q
S
P
A
Site 30
S383
E
P
V
Q
T
L
Y
S
Q
S
P
A
L
E
L
Site 31
S385
V
Q
T
L
Y
S
Q
S
P
A
L
E
L
D
K
Site 32
T405
R
N
G
I
Y
P
L
T
A
F
G
L
P
R
P
Site 33
S422
P
Q
Q
E
E
V
T
S
P
V
V
P
P
S
V
Site 34
S428
T
S
P
V
V
P
P
S
V
K
T
P
T
P
E
Site 35
T431
V
V
P
P
S
V
K
T
P
T
P
E
P
A
E
Site 36
T433
P
P
S
V
K
T
P
T
P
E
P
A
E
V
E
Site 37
T441
P
E
P
A
E
V
E
T
R
K
V
V
L
M
Q
Site 38
T463
E
G
V
K
H
H
L
T
L
L
L
K
L
E
D
Site 39
S477
D
K
L
N
R
H
L
S
C
D
L
M
P
N
E
Site 40
S505
F
I
S
E
A
D
Q
S
R
L
T
S
L
L
E
Site 41
T508
E
A
D
Q
S
R
L
T
S
L
L
E
E
T
L
Site 42
S509
A
D
Q
S
R
L
T
S
L
L
E
E
T
L
N
Site 43
S524
K
F
N
F
A
R
N
S
T
L
N
S
A
A
V
Site 44
T525
F
N
F
A
R
N
S
T
L
N
S
A
A
V
T
Site 45
S528
A
R
N
S
T
L
N
S
A
A
V
T
V
S
S
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation