KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
DrugProNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
Home
|
Kinexus
|
Contact
|
Credits
Protein Info
Short Name:
EVL
Full Name:
Ena/VASP-like protein
Alias:
Ena/vasodilator stimulated phosphoprotein-like protein; Ena/vasodilator-stimulated phosphoprotein-like; Enah/Vasp-like; RNB6
Type:
Cytoskeletal protein
Mass (Da):
44620
Number AA:
416
UniProt ID:
Q9UI08
International Prot ID:
IPI00170979
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005856
GO:0005829
GO:0005925
Uniprot
OncoNet
Molecular Function:
GO:0017124
GO:0003779
GO:0005522
PhosphoSite+
KinaseNET
Biological Process:
GO:0008154
GO:0007166
GO:0007399
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
Y16
A
R
A
S
V
M
V
Y
D
D
T
S
K
K
W
Site 2
T19
S
V
M
V
Y
D
D
T
S
K
K
W
V
P
I
Site 3
Y39
G
F
S
R
I
N
I
Y
H
N
T
A
S
N
T
Site 4
T46
Y
H
N
T
A
S
N
T
F
R
V
V
G
V
K
Site 5
Y63
D
Q
Q
V
V
I
N
Y
S
I
V
K
G
L
K
Site 6
Y71
S
I
V
K
G
L
K
Y
N
Q
A
T
P
T
F
Site 7
Y88
W
R
D
A
R
Q
V
Y
G
L
N
F
A
S
K
Site 8
S94
V
Y
G
L
N
F
A
S
K
E
E
A
T
T
F
Site 9
T100
A
S
K
E
E
A
T
T
F
S
N
A
M
L
F
Site 10
S114
F
A
L
N
I
M
N
S
Q
E
G
G
P
S
S
Site 11
S121
S
Q
E
G
G
P
S
S
Q
R
Q
V
Q
N
G
Site 12
S130
R
Q
V
Q
N
G
P
S
P
D
E
M
D
I
Q
Site 13
S152
H
Q
Q
Q
R
Q
E
S
L
E
R
R
T
S
A
Site 14
T157
Q
E
S
L
E
R
R
T
S
A
T
G
P
I
L
Site 15
S158
E
S
L
E
R
R
T
S
A
T
G
P
I
L
P
Site 16
T160
L
E
R
R
T
S
A
T
G
P
I
L
P
P
G
Site 17
S171
L
P
P
G
H
P
S
S
A
A
S
A
P
V
S
Site 18
S174
G
H
P
S
S
A
A
S
A
P
V
S
C
S
G
Site 19
S178
S
A
A
S
A
P
V
S
C
S
G
P
P
P
P
Site 20
S180
A
S
A
P
V
S
C
S
G
P
P
P
P
P
P
Site 21
T195
P
P
V
P
P
P
P
T
G
A
T
P
P
P
P
Site 22
T198
P
P
P
P
T
G
A
T
P
P
P
P
P
P
L
Site 23
S213
P
A
G
G
A
Q
G
S
S
H
D
E
S
S
M
Site 24
S214
A
G
G
A
Q
G
S
S
H
D
E
S
S
M
S
Site 25
S218
Q
G
S
S
H
D
E
S
S
M
S
G
L
A
A
Site 26
S219
G
S
S
H
D
E
S
S
M
S
G
L
A
A
A
Site 27
S221
S
H
D
E
S
S
M
S
G
L
A
A
A
I
A
Site 28
S242
V
Q
R
P
E
D
A
S
G
G
S
S
P
S
G
Site 29
S245
P
E
D
A
S
G
G
S
S
P
S
G
T
S
K
Site 30
S246
E
D
A
S
G
G
S
S
P
S
G
T
S
K
S
Site 31
S248
A
S
G
G
S
S
P
S
G
T
S
K
S
D
A
Site 32
T250
G
G
S
S
P
S
G
T
S
K
S
D
A
N
R
Site 33
S253
S
P
S
G
T
S
K
S
D
A
N
R
A
S
S
Site 34
S259
K
S
D
A
N
R
A
S
S
G
G
G
G
G
G
Site 35
S260
S
D
A
N
R
A
S
S
G
G
G
G
G
G
L
Site 36
S283
A
K
R
R
K
A
A
S
Q
S
D
K
P
A
E
Site 37
S285
R
R
K
A
A
S
Q
S
D
K
P
A
E
K
K
Site 38
S296
A
E
K
K
E
D
E
S
Q
M
E
D
P
S
T
Site 39
S302
E
S
Q
M
E
D
P
S
T
S
P
S
P
G
T
Site 40
T303
S
Q
M
E
D
P
S
T
S
P
S
P
G
T
R
Site 41
S304
Q
M
E
D
P
S
T
S
P
S
P
G
T
R
A
Site 42
S306
E
D
P
S
T
S
P
S
P
G
T
R
A
A
S
Site 43
T309
S
T
S
P
S
P
G
T
R
A
A
S
Q
P
P
Site 44
S313
S
P
G
T
R
A
A
S
Q
P
P
N
S
S
E
Site 45
S318
A
A
S
Q
P
P
N
S
S
E
A
G
R
K
P
Site 46
S319
A
S
Q
P
P
N
S
S
E
A
G
R
K
P
W
Site 47
S329
G
R
K
P
W
E
R
S
N
S
V
E
K
P
V
Site 48
S331
K
P
W
E
R
S
N
S
V
E
K
P
V
S
S
Site 49
S337
N
S
V
E
K
P
V
S
S
I
L
S
R
T
P
Site 50
S338
S
V
E
K
P
V
S
S
I
L
S
R
T
P
S
Site 51
S341
K
P
V
S
S
I
L
S
R
T
P
S
V
A
K
Site 52
T343
V
S
S
I
L
S
R
T
P
S
V
A
K
S
P
Site 53
S345
S
I
L
S
R
T
P
S
V
A
K
S
P
E
A
Site 54
S349
R
T
P
S
V
A
K
S
P
E
A
K
S
P
L
Site 55
S354
A
K
S
P
E
A
K
S
P
L
Q
S
Q
P
H
Site 56
S358
E
A
K
S
P
L
Q
S
Q
P
H
S
R
M
K
Site 57
S362
P
L
Q
S
Q
P
H
S
R
M
K
P
A
G
S
Site 58
S369
S
R
M
K
P
A
G
S
V
N
D
M
A
L
D
Site 59
S411
D
A
I
R
Q
E
L
S
G
I
S
T
T
_
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation