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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
CTNNA3
Full Name:
Catenin alpha-3
Alias:
Alpha T-catenin; Cadherin-associated protein; Catenin, alpha 3; CTN3; CTNA3; MGC26194; VR22
Type:
Adhesion
Mass (Da):
99809
Number AA:
895
UniProt ID:
Q9UI47
International Prot ID:
IPI00001712
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0015629
GO:0005737
GO:0005916
Uniprot
OncoNet
Molecular Function:
GO:0045296
GO:0005198
PhosphoSite+
KinaseNET
Biological Process:
GO:0016337
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T8
M
S
A
E
T
P
I
T
L
N
I
D
P
Q
D
Site 2
T20
P
Q
D
L
Q
V
Q
T
F
T
V
E
K
L
L
Site 3
T22
D
L
Q
V
Q
T
F
T
V
E
K
L
L
E
P
Site 4
S45
V
N
C
P
Q
N
P
S
S
R
K
K
G
R
S
Site 5
S46
N
C
P
Q
N
P
S
S
R
K
K
G
R
S
K
Site 6
S52
S
S
R
K
K
G
R
S
K
R
A
S
V
L
L
Site 7
S56
K
G
R
S
K
R
A
S
V
L
L
A
S
V
E
Site 8
T88
T
V
L
K
D
E
L
T
A
S
L
E
E
V
R
Site 9
S90
L
K
D
E
L
T
A
S
L
E
E
V
R
K
E
Site 10
S98
L
E
E
V
R
K
E
S
E
A
L
K
V
S
A
Site 11
S104
E
S
E
A
L
K
V
S
A
E
R
F
T
D
D
Site 12
T109
K
V
S
A
E
R
F
T
D
D
P
C
F
L
P
Site 13
T157
H
V
S
A
F
Q
R
T
F
E
S
L
K
N
V
Site 14
S160
A
F
Q
R
T
F
E
S
L
K
N
V
A
N
K
Site 15
S168
L
K
N
V
A
N
K
S
D
L
Q
K
T
Y
Q
Site 16
Y186
K
E
L
E
N
L
D
Y
L
A
F
K
R
Q
Q
Site 17
S197
K
R
Q
Q
D
L
K
S
P
N
Q
R
D
E
I
Site 18
S210
E
I
A
G
A
R
A
S
L
K
E
N
S
P
L
Site 19
S215
R
A
S
L
K
E
N
S
P
L
L
H
S
I
C
Site 20
S233
L
E
H
S
D
V
A
S
L
K
A
S
K
D
T
Site 21
S237
D
V
A
S
L
K
A
S
K
D
T
V
C
E
E
Site 22
T240
S
L
K
A
S
K
D
T
V
C
E
E
I
Q
N
Site 23
T263
S
Q
G
I
Q
N
M
T
T
P
P
E
P
Q
A
Site 24
T264
Q
G
I
Q
N
M
T
T
P
P
E
P
Q
A
A
Site 25
S299
T
E
E
E
I
R
P
S
L
E
K
R
L
E
A
Site 26
S318
A
A
L
L
A
D
S
S
C
T
R
D
L
H
R
Site 27
S344
Q
A
L
Q
D
L
L
S
E
Y
M
N
N
A
G
Site 28
Y346
L
Q
D
L
L
S
E
Y
M
N
N
A
G
K
K
Site 29
S356
N
A
G
K
K
E
R
S
N
T
L
N
I
A
L
Site 30
T358
G
K
K
E
R
S
N
T
L
N
I
A
L
D
N
Site 31
S386
K
A
I
I
D
H
V
S
D
S
F
L
D
T
T
Site 32
Y414
R
E
K
E
I
K
E
Y
A
A
I
F
H
E
H
Site 33
S436
A
N
L
A
C
S
M
S
T
N
E
D
G
I
K
Site 34
S472
A
L
A
A
R
P
K
S
Q
A
V
K
N
T
M
Site 35
T552
A
R
V
A
H
I
V
T
G
E
M
D
S
Y
E
Site 36
S557
I
V
T
G
E
M
D
S
Y
E
P
G
A
Y
T
Site 37
Y558
V
T
G
E
M
D
S
Y
E
P
G
A
Y
T
E
Site 38
Y563
D
S
Y
E
P
G
A
Y
T
E
G
V
M
R
N
Site 39
S596
A
L
E
A
L
S
K
S
S
L
N
V
L
D
D
Site 40
Y614
V
D
I
S
K
K
I
Y
D
T
I
H
D
I
R
Site 41
T616
I
S
K
K
I
Y
D
T
I
H
D
I
R
C
S
Site 42
T629
C
S
V
M
M
I
R
T
P
E
E
L
E
D
V
Site 43
S637
P
E
E
L
E
D
V
S
D
L
E
E
E
H
E
Site 44
S647
E
E
E
H
E
V
R
S
H
T
S
I
Q
T
E
Site 45
T649
E
H
E
V
R
S
H
T
S
I
Q
T
E
G
K
Site 46
S650
H
E
V
R
S
H
T
S
I
Q
T
E
G
K
T
Site 47
T653
R
S
H
T
S
I
Q
T
E
G
K
T
D
R
A
Site 48
T657
S
I
Q
T
E
G
K
T
D
R
A
K
M
T
Q
Site 49
T663
K
T
D
R
A
K
M
T
Q
L
P
E
A
E
K
Site 50
S685
A
D
F
K
K
V
K
S
K
L
D
A
E
I
E
Site 51
T719
M
M
E
M
T
D
F
T
R
G
K
G
P
L
K
Site 52
Y733
K
H
T
T
D
V
I
Y
A
A
K
M
I
S
E
Site 53
S739
I
Y
A
A
K
M
I
S
E
S
G
S
R
M
D
Site 54
S743
K
M
I
S
E
S
G
S
R
M
D
V
L
A
R
Site 55
Y768
C
K
Q
D
L
L
A
Y
L
E
Q
I
K
F
Y
Site 56
S783
S
H
Q
L
K
I
C
S
Q
V
K
A
E
I
Q
Site 57
S837
T
K
I
I
R
I
Q
S
P
A
G
P
R
H
P
Site 58
T867
K
R
E
K
P
E
E
T
C
A
A
V
R
R
G
Site 59
S875
C
A
A
V
R
R
G
S
A
K
K
K
I
H
P
Site 60
S887
I
H
P
L
Q
V
M
S
E
F
R
G
R
Q
I
Site 61
Y895
E
F
R
G
R
Q
I
Y
_
_
_
_
_
_
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation