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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
Cytohesin 4
Full Name:
Cytohesin-4
Alias:
PH, SEC7 and coiled-coil domain-containing protein 4
Type:
Mass (Da):
45672
Number AA:
394
UniProt ID:
Q9UIA0
International Prot ID:
IPI00395879
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005622
Uniprot
OncoNet
Molecular Function:
GO:0005086
PhosphoSite+
KinaseNET
Biological Process:
GO:0032012
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S52
A
Q
I
D
C
F
E
S
A
E
E
S
R
M
A
Site 2
S56
C
F
E
S
A
E
E
S
R
M
A
Q
K
E
K
Site 3
Y82
D
P
A
K
G
I
Q
Y
F
I
E
H
K
L
L
Site 4
Y101
Q
D
I
A
R
F
L
Y
K
G
E
G
L
N
K
Site 5
T109
K
G
E
G
L
N
K
T
A
I
G
T
Y
L
G
Site 6
S150
A
L
R
Q
F
L
W
S
F
R
L
P
G
E
A
Site 7
S198
S
I
I
M
L
N
T
S
L
H
N
P
N
V
R
Site 8
S215
P
P
F
E
R
F
V
S
M
N
R
G
I
N
N
Site 9
S224
N
R
G
I
N
N
G
S
D
L
P
E
D
Q
L
Site 10
S237
Q
L
R
N
L
F
D
S
I
K
S
E
P
F
S
Site 11
S240
N
L
F
D
S
I
K
S
E
P
F
S
I
P
E
Site 12
S244
S
I
K
S
E
P
F
S
I
P
E
D
D
G
N
Site 13
T254
E
D
D
G
N
D
L
T
H
T
F
F
N
P
D
Site 14
T256
D
G
N
D
L
T
H
T
F
F
N
P
D
R
E
Site 15
T275
K
L
G
G
R
V
K
T
W
K
R
R
W
F
I
Site 16
Y290
L
T
D
N
C
L
Y
Y
F
E
F
T
T
D
K
Site 17
S309
I
I
P
L
E
N
L
S
V
Q
K
V
D
D
P
Site 18
Y325
K
P
F
C
L
E
L
Y
N
P
S
C
R
G
Q
Site 19
S352
V
V
E
G
K
H
E
S
Y
R
I
S
A
T
S
Site 20
S356
K
H
E
S
Y
R
I
S
A
T
S
A
E
E
R
Site 21
S359
S
Y
R
I
S
A
T
S
A
E
E
R
D
Q
W
Site 22
S369
E
R
D
Q
W
I
E
S
I
R
A
S
I
T
R
Site 23
Y380
S
I
T
R
V
P
F
Y
D
L
V
S
T
R
K
Site 24
S384
V
P
F
Y
D
L
V
S
T
R
K
K
K
I
A
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation