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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
exportin 7
Full Name:
Exportin-7
Alias:
exportin 7; KIAA0745; Ran-binding protein 16; RANBP16; XPO7
Type:
Karyopherin
Mass (Da):
123907
Number AA:
1087
UniProt ID:
Q9UIA9
International Prot ID:
IPI00302458
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005737
GO:0005643
Uniprot
OncoNet
Molecular Function:
GO:0005049
GO:0008565
PhosphoSite+
KinaseNET
Biological Process:
GO:0051028
GO:0006611
GO:0055085
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
Y19
E
N
L
C
K
Q
L
Y
E
T
T
D
T
T
T
Site 2
T24
Q
L
Y
E
T
T
D
T
T
T
R
L
Q
A
E
Site 3
T25
L
Y
E
T
T
D
T
T
T
R
L
Q
A
E
K
Site 4
S45
T
N
S
P
D
C
L
S
K
C
Q
L
L
L
E
Site 5
S55
Q
L
L
L
E
R
G
S
S
S
Y
S
Q
L
L
Site 6
S57
L
L
E
R
G
S
S
S
Y
S
Q
L
L
A
A
Site 7
Y58
L
E
R
G
S
S
S
Y
S
Q
L
L
A
A
T
Site 8
S59
E
R
G
S
S
S
Y
S
Q
L
L
A
A
T
C
Site 9
T74
L
T
K
L
V
S
R
T
N
N
P
L
P
L
E
Site 10
Y89
Q
R
I
D
I
R
N
Y
V
L
N
Y
L
A
T
Site 11
Y93
I
R
N
Y
V
L
N
Y
L
A
T
R
P
K
L
Site 12
Y128
F
D
C
Q
K
D
D
Y
V
F
R
N
A
I
T
Site 13
T167
N
E
I
N
Q
A
D
T
T
H
P
L
T
K
H
Site 14
T168
E
I
N
Q
A
D
T
T
H
P
L
T
K
H
R
Site 15
T172
A
D
T
T
H
P
L
T
K
H
R
K
I
A
S
Site 16
S179
T
K
H
R
K
I
A
S
S
F
R
D
S
S
L
Site 17
S180
K
H
R
K
I
A
S
S
F
R
D
S
S
L
F
Site 18
T191
S
S
L
F
D
I
F
T
L
S
C
N
L
L
K
Site 19
S201
C
N
L
L
K
Q
A
S
G
K
N
L
N
L
N
Site 20
S211
N
L
N
L
N
D
E
S
Q
H
G
L
L
M
Q
Site 21
S235
N
F
D
F
I
G
T
S
T
D
E
S
S
D
D
Site 22
T236
F
D
F
I
G
T
S
T
D
E
S
S
D
D
L
Site 23
S239
I
G
T
S
T
D
E
S
S
D
D
L
C
T
V
Site 24
S240
G
T
S
T
D
E
S
S
D
D
L
C
T
V
Q
Site 25
T245
E
S
S
D
D
L
C
T
V
Q
I
P
T
S
W
Site 26
S254
Q
I
P
T
S
W
R
S
A
F
L
D
S
S
T
Site 27
S293
Q
I
A
S
V
R
R
S
L
F
N
N
A
E
R
Site 28
S305
A
E
R
A
K
F
L
S
H
L
V
D
G
V
K
Site 29
S320
R
I
L
E
N
P
Q
S
L
S
D
P
N
N
Y
Site 30
S322
L
E
N
P
Q
S
L
S
D
P
N
N
Y
H
E
Site 31
Y327
S
L
S
D
P
N
N
Y
H
E
F
C
R
L
L
Site 32
S339
R
L
L
A
R
L
K
S
N
Y
Q
L
G
E
L
Site 33
Y341
L
A
R
L
K
S
N
Y
Q
L
G
E
L
V
K
Site 34
Y393
R
L
A
A
S
V
P
Y
V
K
A
T
E
P
H
Site 35
T404
T
E
P
H
M
L
E
T
Y
T
P
E
V
T
K
Site 36
T406
P
H
M
L
E
T
Y
T
P
E
V
T
K
A
Y
Site 37
T415
E
V
T
K
A
Y
I
T
S
R
L
E
S
V
H
Site 38
S447
Q
Q
Q
L
D
Q
L
S
T
I
G
R
C
E
Y
Site 39
Y454
S
T
I
G
R
C
E
Y
E
K
T
C
A
L
L
Site 40
S471
L
F
D
Q
S
A
Q
S
Y
Q
E
L
L
Q
S
Site 41
Y472
F
D
Q
S
A
Q
S
Y
Q
E
L
L
Q
S
A
Site 42
S478
S
Y
Q
E
L
L
Q
S
A
S
A
S
P
M
D
Site 43
S480
Q
E
L
L
Q
S
A
S
A
S
P
M
D
I
A
Site 44
S509
A
V
I
G
G
R
V
S
F
A
S
T
D
E
Q
Site 45
S512
G
G
R
V
S
F
A
S
T
D
E
Q
D
A
M
Site 46
T513
G
R
V
S
F
A
S
T
D
E
Q
D
A
M
D
Site 47
S552
K
L
E
L
A
M
L
S
F
F
E
Q
F
R
K
Site 48
Y561
F
E
Q
F
R
K
I
Y
I
G
D
Q
V
Q
K
Site 49
S569
I
G
D
Q
V
Q
K
S
S
K
L
Y
R
R
L
Site 50
Y573
V
Q
K
S
S
K
L
Y
R
R
L
S
E
V
L
Site 51
S577
S
K
L
Y
R
R
L
S
E
V
L
G
L
N
D
Site 52
Y602
K
I
I
T
N
L
K
Y
W
G
R
C
E
P
I
Site 53
T610
W
G
R
C
E
P
I
T
S
K
T
L
Q
L
L
Site 54
S611
G
R
C
E
P
I
T
S
K
T
L
Q
L
L
N
Site 55
Y624
L
N
D
L
S
I
G
Y
S
S
V
R
K
L
V
Site 56
S625
N
D
L
S
I
G
Y
S
S
V
R
K
L
V
K
Site 57
T666
L
T
D
M
R
C
R
T
T
F
Y
T
A
L
G
Site 58
Y687
L
G
E
D
E
D
Q
Y
E
Q
F
M
L
P
L
Site 59
S706
E
A
V
A
Q
M
F
S
T
N
S
F
N
E
Q
Site 60
S709
A
Q
M
F
S
T
N
S
F
N
E
Q
E
A
K
Site 61
T718
N
E
Q
E
A
K
R
T
L
V
G
L
V
R
D
Site 62
Y750
F
E
W
I
Y
P
S
Y
M
P
I
L
Q
R
A
Site 63
Y762
Q
R
A
I
E
L
W
Y
H
D
P
A
C
T
T
Site 64
S783
A
E
L
V
H
N
R
S
Q
R
L
Q
F
D
V
Site 65
S791
Q
R
L
Q
F
D
V
S
S
P
N
G
I
L
L
Site 66
T807
R
E
T
S
K
M
I
T
M
Y
G
N
R
I
L
Site 67
T815
M
Y
G
N
R
I
L
T
L
G
E
V
P
K
D
Site 68
Y825
E
V
P
K
D
Q
V
Y
A
L
K
L
K
G
I
Site 69
Y856
N
F
G
V
F
R
L
Y
G
D
D
A
L
D
N
Site 70
Y883
P
H
S
D
L
L
D
Y
P
K
L
S
Q
S
Y
Site 71
S887
L
L
D
Y
P
K
L
S
Q
S
Y
Y
S
L
L
Site 72
S889
D
Y
P
K
L
S
Q
S
Y
Y
S
L
L
E
V
Site 73
Y891
P
K
L
S
Q
S
Y
Y
S
L
L
E
V
L
T
Site 74
S892
K
L
S
Q
S
Y
Y
S
L
L
E
V
L
T
Q
Site 75
S951
T
Y
L
F
K
Q
L
S
R
S
T
K
K
R
T
Site 76
S953
L
F
K
Q
L
S
R
S
T
K
K
R
T
T
P
Site 77
T954
F
K
Q
L
S
R
S
T
K
K
R
T
T
P
L
Site 78
T959
R
S
T
K
K
R
T
T
P
L
N
Q
E
S
D
Site 79
S965
T
T
P
L
N
Q
E
S
D
R
F
L
H
I
M
Site 80
S1000
E
D
C
R
N
Q
W
S
M
S
R
P
L
L
G
Site 81
S1002
C
R
N
Q
W
S
M
S
R
P
L
L
G
L
I
Site 82
Y1015
L
I
L
L
N
E
K
Y
F
S
D
L
R
N
S
Site 83
S1017
L
L
N
E
K
Y
F
S
D
L
R
N
S
I
V
Site 84
S1022
Y
F
S
D
L
R
N
S
I
V
N
S
Q
P
P
Site 85
S1026
L
R
N
S
I
V
N
S
Q
P
P
E
K
Q
Q
Site 86
T1059
T
K
N
R
D
R
F
T
Q
N
L
S
A
F
R
Site 87
S1063
D
R
F
T
Q
N
L
S
A
F
R
R
E
V
N
Site 88
S1072
F
R
R
E
V
N
D
S
M
K
N
S
T
Y
G
Site 89
S1076
V
N
D
S
M
K
N
S
T
Y
G
V
N
S
N
Site 90
Y1078
D
S
M
K
N
S
T
Y
G
V
N
S
N
D
M
Site 91
S1087
V
N
S
N
D
M
M
S
_
_
_
_
_
_
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation