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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
AK3
Full Name:
GTP:AMP phosphotransferase mitochondrial
Alias:
Adenylate kinase 3; Adenylate kinase 3 alpha-like 1; AK3L1; AK6; AKL3L1; KAD3
Type:
Nucleotide Metabolism - pyrimidine; Transferase; Mitochondrial; EC 2.7.4.10
Mass (Da):
25434
Number AA:
227
UniProt ID:
Q9UIJ7
International Prot ID:
IPI00465256
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005759
Uniprot
OncoNet
Molecular Function:
GO:0005524
GO:0005525
GO:0004017
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S18
V
I
M
G
A
P
G
S
G
K
G
T
V
S
S
Site 2
T22
A
P
G
S
G
K
G
T
V
S
S
R
I
T
T
Site 3
S24
G
S
G
K
G
T
V
S
S
R
I
T
T
H
F
Site 4
S25
S
G
K
G
T
V
S
S
R
I
T
T
H
F
E
Site 5
T28
G
T
V
S
S
R
I
T
T
H
F
E
L
K
H
Site 6
T29
T
V
S
S
R
I
T
T
H
F
E
L
K
H
L
Site 7
S37
H
F
E
L
K
H
L
S
S
G
D
L
L
R
D
Site 8
S38
F
E
L
K
H
L
S
S
G
D
L
L
R
D
N
Site 9
T50
R
D
N
M
L
R
G
T
E
I
G
V
L
A
K
Site 10
T83
L
H
E
L
K
N
L
T
Q
Y
S
W
L
L
D
Site 11
Y85
E
L
K
N
L
T
Q
Y
S
W
L
L
D
G
F
Site 12
Y106
A
E
A
L
D
R
A
Y
Q
I
D
T
V
I
N
Site 13
T110
D
R
A
Y
Q
I
D
T
V
I
N
L
N
V
P
Site 14
T126
E
V
I
K
Q
R
L
T
A
R
W
I
H
P
A
Site 15
Y138
H
P
A
S
G
R
V
Y
N
I
E
F
N
P
P
Site 16
T147
I
E
F
N
P
P
K
T
V
G
I
D
D
L
T
Site 17
T154
T
V
G
I
D
D
L
T
G
E
P
L
I
Q
R
Site 18
T168
R
E
D
D
K
P
E
T
V
I
K
R
L
K
A
Site 19
T180
L
K
A
Y
E
D
Q
T
K
P
V
L
E
Y
Y
Site 20
Y186
Q
T
K
P
V
L
E
Y
Y
Q
K
K
G
V
L
Site 21
Y187
T
K
P
V
L
E
Y
Y
Q
K
K
G
V
L
E
Site 22
T195
Q
K
K
G
V
L
E
T
F
S
G
T
E
T
N
Site 23
S197
K
G
V
L
E
T
F
S
G
T
E
T
N
K
I
Site 24
T201
E
T
F
S
G
T
E
T
N
K
I
W
P
Y
V
Site 25
Y207
E
T
N
K
I
W
P
Y
V
Y
A
F
L
Q
T
Site 26
S220
Q
T
K
V
P
Q
R
S
Q
K
A
S
V
T
P
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation