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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
Plxna1
Full Name:
Plexin-A1
Alias:
NOV; plexin A1; plexin-A1; PLXA1; PLXN1; semaphorin receptor NOV
Type:
Receptor, misc.
Mass (Da):
211087
Number AA:
1896
UniProt ID:
Q9UIW2
International Prot ID:
IPI00552671
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0016021
GO:0005622
GO:0005886
Uniprot
OncoNet
Molecular Function:
GO:0017154
PhosphoSite+
KinaseNET
Biological Process:
GO:0007275
GO:0007165
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
Y122
N
K
L
L
L
L
D
Y
A
A
N
R
L
L
A
Site 2
S1271
L
I
A
Y
K
R
K
S
R
D
A
D
R
T
L
Site 3
T1277
K
S
R
D
A
D
R
T
L
K
R
L
Q
L
Q
Site 4
S1380
R
T
L
E
A
Q
R
S
F
S
M
R
D
R
G
Site 5
S1382
L
E
A
Q
R
S
F
S
M
R
D
R
G
N
V
Site 6
S1391
R
D
R
G
N
V
A
S
L
I
M
T
A
L
Q
Site 7
Y1403
A
L
Q
G
E
M
E
Y
A
T
G
V
L
K
Q
Site 8
S1422
L
I
E
K
N
L
E
S
K
N
H
P
K
L
L
Site 9
T1433
P
K
L
L
L
R
R
T
E
S
V
A
E
K
M
Site 10
S1435
L
L
L
R
R
T
E
S
V
A
E
K
M
L
T
Site 11
T1481
K
G
P
I
D
A
I
T
G
E
A
R
Y
S
L
Site 12
Y1486
A
I
T
G
E
A
R
Y
S
L
S
E
D
K
L
Site 13
S1487
I
T
G
E
A
R
Y
S
L
S
E
D
K
L
I
Site 14
S1489
G
E
A
R
Y
S
L
S
E
D
K
L
I
R
Q
Site 15
Y1500
L
I
R
Q
Q
I
D
Y
K
T
L
T
L
N
C
Site 16
T1502
R
Q
Q
I
D
Y
K
T
L
T
L
N
C
V
N
Site 17
T1504
Q
I
D
Y
K
T
L
T
L
N
C
V
N
P
E
Site 18
T1527
V
K
G
L
D
C
D
T
V
T
Q
A
K
E
K
Site 19
T1529
G
L
D
C
D
T
V
T
Q
A
K
E
K
L
L
Site 20
Y1540
E
K
L
L
D
A
A
Y
K
G
V
P
Y
S
Q
Site 21
S1546
A
Y
K
G
V
P
Y
S
Q
R
P
K
A
A
D
Site 22
T1575
L
Q
D
E
D
V
T
T
K
I
D
N
D
W
K
Site 23
Y1590
R
L
N
T
L
A
H
Y
Q
V
T
D
G
S
S
Site 24
S1596
H
Y
Q
V
T
D
G
S
S
V
A
L
V
P
K
Site 25
S1597
Y
Q
V
T
D
G
S
S
V
A
L
V
P
K
Q
Site 26
Y1608
V
P
K
Q
T
S
A
Y
N
I
S
N
S
S
T
Site 27
S1611
Q
T
S
A
Y
N
I
S
N
S
S
T
F
T
K
Site 28
S1613
S
A
Y
N
I
S
N
S
S
T
F
T
K
S
L
Site 29
T1615
Y
N
I
S
N
S
S
T
F
T
K
S
L
S
R
Site 30
T1617
I
S
N
S
S
T
F
T
K
S
L
S
R
Y
E
Site 31
S1619
N
S
S
T
F
T
K
S
L
S
R
Y
E
S
M
Site 32
S1621
S
T
F
T
K
S
L
S
R
Y
E
S
M
L
R
Site 33
Y1623
F
T
K
S
L
S
R
Y
E
S
M
L
R
T
A
Site 34
S1625
K
S
L
S
R
Y
E
S
M
L
R
T
A
S
S
Site 35
T1629
R
Y
E
S
M
L
R
T
A
S
S
P
D
S
L
Site 36
S1631
E
S
M
L
R
T
A
S
S
P
D
S
L
R
S
Site 37
S1632
S
M
L
R
T
A
S
S
P
D
S
L
R
S
R
Site 38
S1635
R
T
A
S
S
P
D
S
L
R
S
R
T
P
M
Site 39
S1638
S
S
P
D
S
L
R
S
R
T
P
M
I
T
P
Site 40
T1640
P
D
S
L
R
S
R
T
P
M
I
T
P
D
L
Site 41
T1644
R
S
R
T
P
M
I
T
P
D
L
E
S
G
T
Site 42
S1649
M
I
T
P
D
L
E
S
G
T
K
L
W
H
L
Site 43
S1672
Q
R
E
G
D
R
G
S
K
M
V
S
E
I
Y
Site 44
S1676
D
R
G
S
K
M
V
S
E
I
Y
L
T
R
L
Site 45
T1689
R
L
L
A
T
K
G
T
L
Q
K
F
V
D
D
Site 46
S1703
D
L
F
E
T
I
F
S
T
A
H
R
G
S
A
Site 47
S1783
V
A
Q
T
F
M
D
S
C
S
T
S
E
H
K
Site 48
S1785
Q
T
F
M
D
S
C
S
T
S
E
H
K
L
G
Site 49
S1787
F
M
D
S
C
S
T
S
E
H
K
L
G
K
D
Site 50
S1795
E
H
K
L
G
K
D
S
P
S
N
K
L
L
Y
Site 51
S1797
K
L
G
K
D
S
P
S
N
K
L
L
Y
A
K
Site 52
Y1802
S
P
S
N
K
L
L
Y
A
K
D
I
P
N
Y
Site 53
Y1809
Y
A
K
D
I
P
N
Y
K
S
W
V
E
R
Y
Site 54
Y1817
K
S
W
V
E
R
Y
Y
A
D
I
A
K
M
P
Site 55
S1827
I
A
K
M
P
A
I
S
D
Q
D
M
S
A
Y
Site 56
Y1834
S
D
Q
D
M
S
A
Y
L
A
E
Q
S
R
L
Site 57
S1844
E
Q
S
R
L
H
L
S
Q
F
N
S
M
S
A
Site 58
S1857
S
A
L
H
E
I
Y
S
Y
I
T
K
Y
K
D
Site 59
Y1858
A
L
H
E
I
Y
S
Y
I
T
K
Y
K
D
E
Site 60
Y1862
I
Y
S
Y
I
T
K
Y
K
D
E
I
L
A
A
Site 61
S1883
A
R
R
Q
R
L
R
S
K
L
E
Q
V
V
D
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation