KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
DrugProNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
Home
|
Kinexus
|
Contact
|
Credits
Protein Info
Short Name:
ENPP5
Full Name:
Alias:
Type:
Mass (Da):
54666
Number AA:
477
UniProt ID:
Q9UJA9
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T20
A
A
L
S
L
S
T
T
F
S
L
Q
P
D
Q
Site 2
S22
L
S
L
S
T
T
F
S
L
Q
P
D
Q
Q
K
Site 3
S34
Q
Q
K
V
L
L
V
S
F
D
G
F
R
W
D
Site 4
Y42
F
D
G
F
R
W
D
Y
L
Y
K
V
P
T
P
Site 5
Y44
G
F
R
W
D
Y
L
Y
K
V
P
T
P
H
F
Site 6
T72
T
N
V
F
I
T
K
T
Y
P
N
H
Y
T
L
Site 7
Y73
N
V
F
I
T
K
T
Y
P
N
H
Y
T
L
V
Site 8
Y77
T
K
T
Y
P
N
H
Y
T
L
V
T
G
L
F
Site 9
T78
K
T
Y
P
N
H
Y
T
L
V
T
G
L
F
A
Site 10
S103
F
D
P
I
R
N
K
S
F
S
L
D
H
M
N
Site 11
S105
P
I
R
N
K
S
F
S
L
D
H
M
N
I
Y
Site 12
Y112
S
L
D
H
M
N
I
Y
D
S
K
F
W
E
E
Site 13
S134
N
Q
R
A
G
H
T
S
G
A
A
M
W
P
G
Site 14
T142
G
A
A
M
W
P
G
T
D
V
K
I
H
K
R
Site 15
T152
K
I
H
K
R
F
P
T
H
Y
M
P
Y
N
E
Site 16
Y154
H
K
R
F
P
T
H
Y
M
P
Y
N
E
S
V
Site 17
S162
M
P
Y
N
E
S
V
S
F
E
D
R
V
A
K
Site 18
Y186
P
I
N
L
G
L
L
Y
W
E
D
P
D
D
M
Site 19
Y217
D
I
D
K
K
L
G
Y
L
I
Q
M
L
K
K
Site 20
S245
D
H
G
M
T
Q
C
S
E
E
R
L
I
E
L
Site 21
Y255
R
L
I
E
L
D
Q
Y
L
D
K
D
H
Y
T
Site 22
Y261
Q
Y
L
D
K
D
H
Y
T
L
I
D
Q
S
P
Site 23
T262
Y
L
D
K
D
H
Y
T
L
I
D
Q
S
P
V
Site 24
Y283
E
G
K
F
D
E
V
Y
E
A
L
T
H
A
H
Site 25
T294
T
H
A
H
P
N
L
T
V
Y
K
K
E
D
V
Site 26
Y307
D
V
P
E
R
W
H
Y
K
Y
N
S
R
I
Q
Site 27
Y309
P
E
R
W
H
Y
K
Y
N
S
R
I
Q
P
I
Site 28
S370
F
S
K
E
A
M
N
S
T
D
L
Y
P
L
L
Site 29
S419
S
T
I
L
L
P
G
S
V
K
P
A
E
Y
D
Site 30
Y425
G
S
V
K
P
A
E
Y
D
Q
E
G
S
Y
P
Site 31
S430
A
E
Y
D
Q
E
G
S
Y
P
Y
F
I
G
V
Site 32
Y431
E
Y
D
Q
E
G
S
Y
P
Y
F
I
G
V
S
Site 33
Y433
D
Q
E
G
S
Y
P
Y
F
I
G
V
S
L
G
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation