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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
ZNF643
Full Name:
Alias:
Type:
Mass (Da):
49925
Number AA:
432
UniProt ID:
Q9UJL9
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S10
E
N
Y
G
N
L
V
S
V
G
C
Q
L
S
K
Site 2
S22
L
S
K
P
G
V
I
S
Q
L
E
K
G
E
E
Site 3
S38
W
L
M
E
R
D
I
S
G
V
P
S
S
D
L
Site 4
S42
R
D
I
S
G
V
P
S
S
D
L
K
S
K
T
Site 5
S43
D
I
S
G
V
P
S
S
D
L
K
S
K
T
K
Site 6
S47
V
P
S
S
D
L
K
S
K
T
K
T
K
E
S
Site 7
T49
S
S
D
L
K
S
K
T
K
T
K
E
S
A
L
Site 8
T51
D
L
K
S
K
T
K
T
K
E
S
A
L
Q
N
Site 9
S61
S
A
L
Q
N
D
I
S
W
E
E
L
H
C
G
Site 10
T75
G
L
M
M
E
R
F
T
K
G
S
S
M
Y
S
Site 11
S78
M
E
R
F
T
K
G
S
S
M
Y
S
T
L
G
Site 12
S79
E
R
F
T
K
G
S
S
M
Y
S
T
L
G
R
Site 13
S82
T
K
G
S
S
M
Y
S
T
L
G
R
I
S
K
Site 14
T83
K
G
S
S
M
Y
S
T
L
G
R
I
S
K
C
Site 15
S88
Y
S
T
L
G
R
I
S
K
C
N
K
L
E
S
Site 16
S95
S
K
C
N
K
L
E
S
Q
Q
E
N
Q
R
M
Site 17
T114
I
P
L
M
C
K
K
T
F
T
Q
E
R
G
Q
Site 18
T116
L
M
C
K
K
T
F
T
Q
E
R
G
Q
E
S
Site 19
S123
T
Q
E
R
G
Q
E
S
N
R
F
E
K
R
I
Site 20
S134
E
K
R
I
N
V
K
S
E
V
M
P
G
P
I
Site 21
Y151
P
R
K
R
D
R
K
Y
D
T
P
G
K
R
S
Site 22
T153
K
R
D
R
K
Y
D
T
P
G
K
R
S
R
Y
Site 23
Y160
T
P
G
K
R
S
R
Y
N
I
D
L
V
N
H
Site 24
Y171
L
V
N
H
S
R
S
Y
T
K
M
K
T
F
E
Site 25
T172
V
N
H
S
R
S
Y
T
K
M
K
T
F
E
C
Site 26
T200
T
E
H
M
R
I
H
T
G
E
K
P
F
R
C
Site 27
S215
K
E
C
G
K
A
F
S
Q
S
S
S
L
I
P
Site 28
S217
C
G
K
A
F
S
Q
S
S
S
L
I
P
H
Q
Site 29
S219
K
A
F
S
Q
S
S
S
L
I
P
H
Q
R
I
Site 30
T228
I
P
H
Q
R
I
H
T
G
E
K
P
Y
E
C
Site 31
Y233
I
H
T
G
E
K
P
Y
E
C
K
E
C
G
K
Site 32
T241
E
C
K
E
C
G
K
T
F
R
H
P
S
S
L
Site 33
S246
G
K
T
F
R
H
P
S
S
L
T
Q
H
V
R
Site 34
S247
K
T
F
R
H
P
S
S
L
T
Q
H
V
R
I
Site 35
T249
F
R
H
P
S
S
L
T
Q
H
V
R
I
H
T
Site 36
T256
T
Q
H
V
R
I
H
T
G
E
K
P
Y
E
C
Site 37
Y261
I
H
T
G
E
K
P
Y
E
C
R
V
C
E
K
Site 38
T282
G
L
I
Q
H
L
R
T
H
V
R
E
K
P
F
Site 39
T290
H
V
R
E
K
P
F
T
C
K
D
C
G
K
A
Site 40
T312
R
Q
H
E
I
I
H
T
G
V
K
P
Y
I
C
Site 41
S327
N
V
C
S
K
T
F
S
H
S
T
Y
L
T
Q
Site 42
T330
S
K
T
F
S
H
S
T
Y
L
T
Q
H
Q
R
Site 43
Y331
K
T
F
S
H
S
T
Y
L
T
Q
H
Q
R
T
Site 44
T333
F
S
H
S
T
Y
L
T
Q
H
Q
R
T
H
T
Site 45
T340
T
Q
H
Q
R
T
H
T
G
E
R
P
Y
K
C
Site 46
Y345
T
H
T
G
E
R
P
Y
K
C
K
E
C
G
K
Site 47
S355
K
E
C
G
K
A
F
S
Q
R
I
H
L
S
I
Site 48
T368
S
I
H
Q
R
V
H
T
G
V
K
P
Y
E
C
Site 49
Y373
V
H
T
G
V
K
P
Y
E
C
S
H
C
G
K
Site 50
S386
G
K
A
F
R
H
D
S
S
F
A
K
H
Q
R
Site 51
S387
K
A
F
R
H
D
S
S
F
A
K
H
Q
R
I
Site 52
T396
A
K
H
Q
R
I
H
T
G
E
K
P
Y
D
C
Site 53
Y401
I
H
T
G
E
K
P
Y
D
C
N
E
C
G
K
Site 54
S411
N
E
C
G
K
A
F
S
C
S
S
S
L
I
R
Site 55
S415
K
A
F
S
C
S
S
S
L
I
R
H
C
K
T
Site 56
T422
S
L
I
R
H
C
K
T
H
L
R
N
T
F
S
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation