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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
HAO1
Full Name:
Hydroxyacid oxidase 1
Alias:
EC 1.1.3.15; Glycolate oxidase; GOX; HAOX1
Type:
Enzyme - Oxidase. 2-hydroxyacid oxidase activity on the 2-carbon substrate glycolate and on 2-hydroxy fatty acids.
Mass (Da):
40924
Number AA:
370
UniProt ID:
Q9UJM8
International Prot ID:
IPI00006934
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005777
Uniprot
OncoNet
Molecular Function:
GO:0003973
GO:0010181
GO:0009055
PhosphoSite+
KinaseNET
Biological Process:
GO:0001561
GO:0046487
GO:0055114
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
Y11
R
L
I
C
I
N
D
Y
E
Q
H
A
K
S
V
Site 2
S17
D
Y
E
Q
H
A
K
S
V
L
P
K
S
I
Y
Site 3
S22
A
K
S
V
L
P
K
S
I
Y
D
Y
Y
R
S
Site 4
Y24
S
V
L
P
K
S
I
Y
D
Y
Y
R
S
G
A
Site 5
Y26
L
P
K
S
I
Y
D
Y
Y
R
S
G
A
N
D
Site 6
Y27
P
K
S
I
Y
D
Y
Y
R
S
G
A
N
D
E
Site 7
T36
S
G
A
N
D
E
E
T
L
A
D
N
I
A
A
Site 8
Y50
A
F
S
R
W
K
L
Y
P
R
M
L
R
N
V
Site 9
S63
N
V
A
E
T
D
L
S
T
S
V
L
G
Q
R
Site 10
S65
A
E
T
D
L
S
T
S
V
L
G
Q
R
V
S
Site 11
S113
M
L
S
S
W
A
T
S
S
I
E
E
V
A
E
Site 12
S114
L
S
S
W
A
T
S
S
I
E
E
V
A
E
A
Site 13
Y132
A
L
R
W
L
Q
L
Y
I
Y
K
D
R
E
V
Site 14
Y134
R
W
L
Q
L
Y
I
Y
K
D
R
E
V
T
K
Site 15
T140
I
Y
K
D
R
E
V
T
K
K
L
V
R
Q
A
Site 16
Y152
R
Q
A
E
K
M
G
Y
K
A
I
F
V
T
V
Site 17
Y163
F
V
T
V
D
T
P
Y
L
G
N
R
L
D
D
Site 18
T188
L
R
M
K
N
F
E
T
S
T
L
S
F
S
P
Site 19
T190
M
K
N
F
E
T
S
T
L
S
F
S
P
E
E
Site 20
S192
N
F
E
T
S
T
L
S
F
S
P
E
E
N
F
Site 21
S194
E
T
S
T
L
S
F
S
P
E
E
N
F
G
D
Site 22
Y208
D
D
S
G
L
A
A
Y
V
A
K
A
I
D
P
Site 23
S216
V
A
K
A
I
D
P
S
I
S
W
E
D
I
K
Site 24
S218
K
A
I
D
P
S
I
S
W
E
D
I
K
W
L
Site 25
T229
I
K
W
L
R
R
L
T
S
L
P
I
V
A
K
Site 26
S230
K
W
L
R
R
L
T
S
L
P
I
V
A
K
G
Site 27
T298
D
G
G
V
R
K
G
T
D
V
L
K
A
L
A
Site 28
T358
N
V
K
V
I
D
K
T
L
V
R
K
N
P
L
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation