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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
FBXL7
Full Name:
Alias:
Type:
Mass (Da):
54575
Number AA:
491
UniProt ID:
Q9UJT9
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
Y9
G
A
N
N
G
K
Q
Y
G
S
E
G
K
G
S
Site 2
S11
N
N
G
K
Q
Y
G
S
E
G
K
G
S
S
S
Site 3
S16
Y
G
S
E
G
K
G
S
S
S
I
S
S
D
V
Site 4
S17
G
S
E
G
K
G
S
S
S
I
S
S
D
V
S
Site 5
S18
S
E
G
K
G
S
S
S
I
S
S
D
V
S
S
Site 6
S20
G
K
G
S
S
S
I
S
S
D
V
S
S
S
T
Site 7
S21
K
G
S
S
S
I
S
S
D
V
S
S
S
T
D
Site 8
S24
S
S
I
S
S
D
V
S
S
S
T
D
H
T
P
Site 9
S25
S
I
S
S
D
V
S
S
S
T
D
H
T
P
T
Site 10
S26
I
S
S
D
V
S
S
S
T
D
H
T
P
T
K
Site 11
T30
V
S
S
S
T
D
H
T
P
T
K
A
Q
K
N
Site 12
S41
A
Q
K
N
V
A
T
S
E
D
S
D
L
S
M
Site 13
S44
N
V
A
T
S
E
D
S
D
L
S
M
R
T
L
Site 14
S47
T
S
E
D
S
D
L
S
M
R
T
L
S
T
P
Site 15
T50
D
S
D
L
S
M
R
T
L
S
T
P
S
P
A
Site 16
S73
G
F
Q
N
G
R
G
S
S
T
S
S
S
S
I
Site 17
S74
F
Q
N
G
R
G
S
S
T
S
S
S
S
I
T
Site 18
T75
Q
N
G
R
G
S
S
T
S
S
S
S
I
T
G
Site 19
S76
N
G
R
G
S
S
T
S
S
S
S
I
T
G
E
Site 20
S77
G
R
G
S
S
T
S
S
S
S
I
T
G
E
T
Site 21
S78
R
G
S
S
T
S
S
S
S
I
T
G
E
T
V
Site 22
S79
G
S
S
T
S
S
S
S
I
T
G
E
T
V
A
Site 23
T84
S
S
S
I
T
G
E
T
V
A
M
V
H
S
P
Site 24
S90
E
T
V
A
M
V
H
S
P
P
P
T
R
L
T
Site 25
T94
M
V
H
S
P
P
P
T
R
L
T
H
P
L
I
Site 26
T97
S
P
P
P
T
R
L
T
H
P
L
I
R
L
A
Site 27
S105
H
P
L
I
R
L
A
S
R
P
Q
K
E
Q
A
Site 28
S113
R
P
Q
K
E
Q
A
S
I
D
R
L
P
D
H
Site 29
T156
W
D
P
R
L
W
R
T
I
R
L
T
G
E
T
Site 30
T160
L
W
R
T
I
R
L
T
G
E
T
I
N
V
D
Site 31
T181
T
R
R
L
C
Q
D
T
P
N
V
C
L
M
L
Site 32
S194
M
L
E
T
V
T
V
S
G
C
R
R
L
T
D
Site 33
T200
V
S
G
C
R
R
L
T
D
R
G
L
Y
T
I
Site 34
Y205
R
L
T
D
R
G
L
Y
T
I
A
Q
C
C
P
Site 35
S220
E
L
R
R
L
E
V
S
G
C
Y
N
I
S
N
Site 36
S246
N
L
E
H
L
D
V
S
G
C
S
K
V
T
C
Site 37
S261
I
S
L
T
R
E
A
S
I
K
L
S
P
L
H
Site 38
S265
R
E
A
S
I
K
L
S
P
L
H
G
K
Q
I
Site 39
S273
P
L
H
G
K
Q
I
S
I
R
Y
L
D
M
T
Site 40
Y276
G
K
Q
I
S
I
R
Y
L
D
M
T
D
C
F
Site 41
T292
L
E
D
E
G
L
H
T
I
A
A
H
C
T
Q
Site 42
T312
L
R
R
C
V
R
L
T
D
E
G
L
R
Y
L
Site 43
S332
S
I
K
E
L
S
V
S
D
C
R
F
V
S
D
Site 44
Y354
K
L
E
S
R
L
R
Y
L
S
I
A
H
C
G
Site 45
S356
E
S
R
L
R
Y
L
S
I
A
H
C
G
R
V
Site 46
Y370
V
T
D
V
G
I
R
Y
V
A
K
Y
C
S
K
Site 47
Y374
G
I
R
Y
V
A
K
Y
C
S
K
L
R
Y
L
Site 48
Y380
K
Y
C
S
K
L
R
Y
L
N
A
R
G
C
E
Site 49
Y396
I
T
D
H
G
V
E
Y
L
A
K
N
C
T
K
Site 50
T402
E
Y
L
A
K
N
C
T
K
L
K
S
L
D
I
Site 51
S406
K
N
C
T
K
L
K
S
L
D
I
G
K
C
P
Site 52
S434
C
F
N
L
K
R
L
S
L
K
S
C
E
S
I
Site 53
S437
L
K
R
L
S
L
K
S
C
E
S
I
T
G
Q
Site 54
S440
L
S
L
K
S
C
E
S
I
T
G
Q
G
L
Q
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation