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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
dynactin 4
Full Name:
Dynactin subunit 4
Alias:
DCTN4; dynactin 4 (p62); dynactin subunit p62
Type:
Motor protein
Mass (Da):
52337
Number AA:
460
UniProt ID:
Q9UJW0
International Prot ID:
IPI00550852
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005813
GO:0005634
Uniprot
OncoNet
Molecular Function:
GO:0047485
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
Y12
L
Q
S
D
R
V
L
Y
L
V
Q
G
E
K
K
Site 2
S25
K
K
V
R
A
P
L
S
Q
L
Y
F
C
R
Y
Site 3
Y28
R
A
P
L
S
Q
L
Y
F
C
R
Y
C
S
E
Site 4
Y32
S
Q
L
Y
F
C
R
Y
C
S
E
L
R
S
L
Site 5
S38
R
Y
C
S
E
L
R
S
L
E
C
V
S
H
E
Site 6
S43
L
R
S
L
E
C
V
S
H
E
V
D
S
H
Y
Site 7
Y50
S
H
E
V
D
S
H
Y
C
P
S
C
L
E
N
Site 8
S60
S
C
L
E
N
M
P
S
A
E
A
K
L
K
K
Site 9
T82
D
C
P
G
C
M
H
T
L
S
T
R
A
T
S
Site 10
S84
P
G
C
M
H
T
L
S
T
R
A
T
S
I
S
Site 11
T85
G
C
M
H
T
L
S
T
R
A
T
S
I
S
T
Site 12
T88
H
T
L
S
T
R
A
T
S
I
S
T
Q
L
P
Site 13
S89
T
L
S
T
R
A
T
S
I
S
T
Q
L
P
D
Site 14
S91
S
T
R
A
T
S
I
S
T
Q
L
P
D
D
P
Site 15
T101
L
P
D
D
P
A
K
T
T
M
K
K
A
Y
Y
Site 16
Y107
K
T
T
M
K
K
A
Y
Y
L
A
C
G
F
C
Site 17
Y108
T
T
M
K
K
A
Y
Y
L
A
C
G
F
C
R
Site 18
S127
D
V
G
M
A
D
K
S
V
A
S
G
G
W
Q
Site 19
T141
Q
E
P
E
N
P
H
T
Q
R
M
N
K
L
I
Site 20
Y150
R
M
N
K
L
I
E
Y
Y
Q
Q
L
A
Q
K
Site 21
Y173
K
L
A
R
R
R
N
Y
M
P
L
A
F
S
D
Site 22
S179
N
Y
M
P
L
A
F
S
D
K
Y
G
L
G
T
Site 23
Y182
P
L
A
F
S
D
K
Y
G
L
G
T
R
L
Q
Site 24
S196
Q
R
P
R
A
G
A
S
I
S
T
L
A
G
L
Site 25
Y232
V
E
P
L
P
E
D
Y
Y
T
R
P
V
N
L
Site 26
Y233
E
P
L
P
E
D
Y
Y
T
R
P
V
N
L
T
Site 27
T234
P
L
P
E
D
Y
Y
T
R
P
V
N
L
T
E
Site 28
T240
Y
T
R
P
V
N
L
T
E
V
T
T
L
Q
Q
Site 29
S260
D
F
Q
P
V
C
A
S
Q
L
Y
P
R
H
K
Site 30
Y263
P
V
C
A
S
Q
L
Y
P
R
H
K
H
L
L
Site 31
S274
K
H
L
L
I
K
R
S
L
R
C
R
K
C
E
Site 32
S285
R
K
C
E
H
N
L
S
K
P
E
F
N
P
T
Site 33
T292
S
K
P
E
F
N
P
T
S
I
K
F
K
I
Q
Site 34
S293
K
P
E
F
N
P
T
S
I
K
F
K
I
Q
L
Site 35
Y319
M
S
I
P
N
L
R
Y
M
K
E
S
Q
V
L
Site 36
S323
N
L
R
Y
M
K
E
S
Q
V
L
L
T
L
T
Site 37
Y376
G
K
D
A
A
A
E
Y
D
E
L
A
E
P
Q
Site 38
T407
V
G
I
F
I
K
V
T
P
Q
R
E
E
G
E
Site 39
T416
Q
R
E
E
G
E
V
T
V
C
F
K
M
K
H
Site 40
S438
P
I
R
P
I
E
E
S
D
Q
G
T
E
V
I
Site 41
T442
I
E
E
S
D
Q
G
T
E
V
I
W
L
T
Q
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation