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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
ZNF222
Full Name:
Alias:
Type:
Mass (Da):
52484
Number AA:
451
UniProt ID:
Q9UK12
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
Y33
D
P
A
Q
R
K
L
Y
R
D
V
M
L
E
N
Site 2
S46
E
N
F
R
N
L
L
S
V
G
G
K
I
Q
T
Site 3
T57
K
I
Q
T
E
M
E
T
V
P
E
A
G
T
H
Site 4
S78
Q
I
W
E
Q
I
A
S
D
L
T
R
S
Q
D
Site 5
T81
E
Q
I
A
S
D
L
T
R
S
Q
D
T
T
I
Site 6
S83
I
A
S
D
L
T
R
S
Q
D
T
T
I
S
N
Site 7
T87
L
T
R
S
Q
D
T
T
I
S
N
S
Q
L
F
Site 8
S89
R
S
Q
D
T
T
I
S
N
S
Q
L
F
E
Q
Site 9
S91
Q
D
T
T
I
S
N
S
Q
L
F
E
Q
D
D
Site 10
S101
F
E
Q
D
D
N
P
S
Q
I
K
A
R
L
S
Site 11
S108
S
Q
I
K
A
R
L
S
T
V
H
T
R
E
K
Site 12
T109
Q
I
K
A
R
L
S
T
V
H
T
R
E
K
P
Site 13
T112
A
R
L
S
T
V
H
T
R
E
K
P
F
Q
G
Site 14
S130
K
Q
F
F
S
D
V
S
F
F
D
L
P
Q
Q
Site 15
Y139
F
D
L
P
Q
Q
L
Y
S
G
E
K
S
H
T
Site 16
S140
D
L
P
Q
Q
L
Y
S
G
E
K
S
H
T
C
Site 17
S144
Q
L
Y
S
G
E
K
S
H
T
C
D
E
C
G
Site 18
T146
Y
S
G
E
K
S
H
T
C
D
E
C
G
K
S
Site 19
S183
D
V
C
G
K
E
F
S
Q
S
S
R
L
Q
T
Site 20
S185
C
G
K
E
F
S
Q
S
S
R
L
Q
T
H
Q
Site 21
T190
S
Q
S
S
R
L
Q
T
H
Q
R
V
H
T
G
Site 22
T196
Q
T
H
Q
R
V
H
T
G
E
K
P
F
K
C
Site 23
S214
G
K
G
F
R
C
R
S
A
L
K
V
H
C
K
Site 24
Y229
L
H
M
R
E
K
P
Y
N
C
E
K
C
G
K
Site 25
T252
Q
K
H
H
R
I
H
T
G
E
K
P
F
K
C
Site 26
S265
K
C
E
I
C
G
K
S
F
C
L
R
S
S
L
Site 27
Y285
V
H
T
A
E
K
L
Y
K
S
E
K
Y
G
R
Site 28
S287
T
A
E
K
L
Y
K
S
E
K
Y
G
R
G
F
Site 29
Y290
K
L
Y
K
S
E
K
Y
G
R
G
F
I
D
R
Site 30
Y313
I
H
M
G
Q
K
P
Y
N
C
K
E
C
G
K
Site 31
S326
G
K
S
F
K
W
S
S
Y
L
L
V
H
Q
R
Site 32
T336
L
V
H
Q
R
V
H
T
G
E
K
P
Y
K
C
Site 33
Y350
C
E
E
C
G
K
G
Y
I
S
K
S
G
L
D
Site 34
S354
G
K
G
Y
I
S
K
S
G
L
D
F
H
H
R
Site 35
T362
G
L
D
F
H
H
R
T
H
T
G
E
R
S
Y
Site 36
T364
D
F
H
H
R
T
H
T
G
E
R
S
Y
N
C
Site 37
Y369
T
H
T
G
E
R
S
Y
N
C
D
N
C
G
K
Site 38
S382
G
K
S
F
R
H
A
S
S
I
L
N
H
K
K
Site 39
S410
G
K
R
L
V
C
R
S
Y
C
K
D
Q
Q
R
Site 40
Y411
K
R
L
V
C
R
S
Y
C
K
D
Q
Q
R
D
Site 41
S420
K
D
Q
Q
R
D
H
S
G
E
N
P
S
K
C
Site 42
S425
D
H
S
G
E
N
P
S
K
C
E
D
C
G
K
Site 43
Y434
C
E
D
C
G
K
R
Y
K
R
R
L
N
L
D
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation