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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
CCNL1
Full Name:
ISOFORM 2 OF CYCLIN-L1.
Alias:
BM-001; CCN1; Cyclin-L1: Cyclin-L1: Cyclin-L1
Type:
Protein-serine kinase regulatory subunit, activator, cyclin
Mass (Da):
59634
Number AA:
526
UniProt ID:
Q9UK58
International Prot ID:
IPI00654682
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0016607
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
GO:0045449
GO:0006350
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S21
A
A
S
S
A
A
P
S
A
G
G
S
S
S
G
Site 2
S25
A
A
P
S
A
G
G
S
S
S
G
T
T
T
T
Site 3
S27
P
S
A
G
G
S
S
S
G
T
T
T
T
T
T
Site 4
T29
A
G
G
S
S
S
G
T
T
T
T
T
T
T
T
Site 5
T30
G
G
S
S
S
G
T
T
T
T
T
T
T
T
T
Site 6
T31
G
S
S
S
G
T
T
T
T
T
T
T
T
T
G
Site 7
T32
S
S
S
G
T
T
T
T
T
T
T
T
T
G
G
Site 8
T33
S
S
G
T
T
T
T
T
T
T
T
T
G
G
I
Site 9
T34
S
G
T
T
T
T
T
T
T
T
T
G
G
I
L
Site 10
T37
T
T
T
T
T
T
T
T
G
G
I
L
I
G
D
Site 11
S51
D
R
L
Y
S
E
V
S
L
T
I
D
H
S
L
Site 12
S65
L
I
P
E
E
R
L
S
P
T
P
S
M
Q
D
Site 13
T67
P
E
E
R
L
S
P
T
P
S
M
Q
D
G
L
Site 14
S69
E
R
L
S
P
T
P
S
M
Q
D
G
L
D
L
Site 15
S78
Q
D
G
L
D
L
P
S
E
T
D
L
R
I
L
Site 16
Y116
V
L
F
H
R
F
F
Y
S
K
S
F
V
K
H
Site 17
T164
R
Q
L
R
G
K
R
T
P
S
P
L
I
L
D
Site 18
S166
L
R
G
K
R
T
P
S
P
L
I
L
D
Q
N
Site 19
Y174
P
L
I
L
D
Q
N
Y
I
N
T
K
N
Q
V
Site 20
T219
L
E
C
E
R
N
Q
T
L
V
Q
T
A
W
N
Site 21
Y227
L
V
Q
T
A
W
N
Y
M
N
D
S
L
R
T
Site 22
T285
I
Q
E
I
C
I
E
T
L
R
L
Y
T
R
K
Site 23
Y289
C
I
E
T
L
R
L
Y
T
R
K
K
P
N
Y
Site 24
T290
I
E
T
L
R
L
Y
T
R
K
K
P
N
Y
E
Site 25
Y296
Y
T
R
K
K
P
N
Y
E
L
L
E
K
E
V
Site 26
T325
K
G
L
N
P
D
G
T
P
A
L
S
T
L
G
Site 27
S329
P
D
G
T
P
A
L
S
T
L
G
G
F
S
P
Site 28
T330
D
G
T
P
A
L
S
T
L
G
G
F
S
P
A
Site 29
S335
L
S
T
L
G
G
F
S
P
A
S
K
P
S
S
Site 30
S338
L
G
G
F
S
P
A
S
K
P
S
S
P
R
E
Site 31
S341
F
S
P
A
S
K
P
S
S
P
R
E
V
K
A
Site 32
S342
S
P
A
S
K
P
S
S
P
R
E
V
K
A
E
Site 33
S352
E
V
K
A
E
E
K
S
P
I
S
I
N
V
K
Site 34
S355
A
E
E
K
S
P
I
S
I
N
V
K
T
V
K
Site 35
T360
P
I
S
I
N
V
K
T
V
K
K
E
P
E
D
Site 36
S372
P
E
D
R
Q
Q
A
S
K
S
P
Y
N
G
V
Site 37
S374
D
R
Q
Q
A
S
K
S
P
Y
N
G
V
R
K
Site 38
S383
Y
N
G
V
R
K
D
S
K
R
S
R
N
S
R
Site 39
S386
V
R
K
D
S
K
R
S
R
N
S
R
S
A
S
Site 40
S389
D
S
K
R
S
R
N
S
R
S
A
S
R
S
R
Site 41
S391
K
R
S
R
N
S
R
S
A
S
R
S
R
S
R
Site 42
S393
S
R
N
S
R
S
A
S
R
S
R
S
R
T
R
Site 43
S395
N
S
R
S
A
S
R
S
R
S
R
T
R
S
R
Site 44
S397
R
S
A
S
R
S
R
S
R
T
R
S
R
S
R
Site 45
T399
A
S
R
S
R
S
R
T
R
S
R
S
R
S
H
Site 46
S401
R
S
R
S
R
T
R
S
R
S
R
S
H
T
P
Site 47
S403
R
S
R
T
R
S
R
S
R
S
H
T
P
R
R
Site 48
S405
R
T
R
S
R
S
R
S
H
T
P
R
R
H
Y
Site 49
T407
R
S
R
S
R
S
H
T
P
R
R
H
Y
N
N
Site 50
Y412
S
H
T
P
R
R
H
Y
N
N
R
R
S
R
S
Site 51
S417
R
H
Y
N
N
R
R
S
R
S
G
T
Y
S
S
Site 52
S419
Y
N
N
R
R
S
R
S
G
T
Y
S
S
R
S
Site 53
T421
N
R
R
S
R
S
G
T
Y
S
S
R
S
R
S
Site 54
Y422
R
R
S
R
S
G
T
Y
S
S
R
S
R
S
R
Site 55
S423
R
S
R
S
G
T
Y
S
S
R
S
R
S
R
S
Site 56
S424
S
R
S
G
T
Y
S
S
R
S
R
S
R
S
R
Site 57
S426
S
G
T
Y
S
S
R
S
R
S
R
S
R
S
H
Site 58
S428
T
Y
S
S
R
S
R
S
R
S
R
S
H
S
E
Site 59
S430
S
S
R
S
R
S
R
S
R
S
H
S
E
S
P
Site 60
S432
R
S
R
S
R
S
R
S
H
S
E
S
P
R
R
Site 61
S434
R
S
R
S
R
S
H
S
E
S
P
R
R
H
H
Site 62
S436
R
S
R
S
H
S
E
S
P
R
R
H
H
N
H
Site 63
S445
R
R
H
H
N
H
G
S
P
H
L
K
A
K
H
Site 64
S459
H
T
R
D
D
L
K
S
S
N
R
H
G
H
K
Site 65
S460
T
R
D
D
L
K
S
S
N
R
H
G
H
K
R
Site 66
S470
H
G
H
K
R
K
K
S
R
S
R
S
Q
S
K
Site 67
S472
H
K
R
K
K
S
R
S
R
S
Q
S
K
S
R
Site 68
S474
R
K
K
S
R
S
R
S
Q
S
K
S
R
D
H
Site 69
S476
K
S
R
S
R
S
Q
S
K
S
R
D
H
S
D
Site 70
S478
R
S
R
S
Q
S
K
S
R
D
H
S
D
A
A
Site 71
S482
Q
S
K
S
R
D
H
S
D
A
A
K
K
H
R
Site 72
S502
H
R
D
R
R
E
R
S
R
S
F
E
R
S
H
Site 73
S504
D
R
R
E
R
S
R
S
F
E
R
S
H
K
S
Site 74
S508
R
S
R
S
F
E
R
S
H
K
S
K
H
H
G
Site 75
S511
S
F
E
R
S
H
K
S
K
H
H
G
G
S
R
Site 76
S517
K
S
K
H
H
G
G
S
R
S
G
H
G
R
H
Site 77
S519
K
H
H
G
G
S
R
S
G
H
G
R
H
R
R
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation