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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
FEM1B
Full Name:
Alias:
Type:
Mass (Da):
70264
Number AA:
627
UniProt ID:
Q9UK73
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
Y7
_
M
E
G
L
A
G
Y
V
Y
K
A
A
S
E
Site 2
Y9
E
G
L
A
G
Y
V
Y
K
A
A
S
E
G
K
Site 3
S28
A
A
L
L
L
N
R
S
E
S
D
I
R
Y
L
Site 4
S30
L
L
L
N
R
S
E
S
D
I
R
Y
L
L
G
Site 5
Y34
R
S
E
S
D
I
R
Y
L
L
G
Y
V
S
Q
Site 6
Y38
D
I
R
Y
L
L
G
Y
V
S
Q
Q
G
G
Q
Site 7
S40
R
Y
L
L
G
Y
V
S
Q
Q
G
G
Q
R
S
Site 8
S47
S
Q
Q
G
G
Q
R
S
T
P
L
I
I
A
A
Site 9
T48
Q
Q
G
G
Q
R
S
T
P
L
I
I
A
A
R
Site 10
T73
L
E
H
Y
R
V
Q
T
Q
Q
T
G
T
V
R
Site 11
T78
V
Q
T
Q
Q
T
G
T
V
R
F
D
G
Y
V
Site 12
T118
G
A
N
V
N
H
T
T
V
T
N
S
T
P
L
Site 13
T123
H
T
T
V
T
N
S
T
P
L
R
A
A
C
F
Site 14
Y139
G
R
L
D
I
V
K
Y
L
V
E
N
N
A
N
Site 15
S240
D
V
V
E
L
L
L
S
H
A
D
C
D
R
R
Site 16
S248
H
A
D
C
D
R
R
S
R
I
E
A
L
E
L
Site 17
S259
A
L
E
L
L
G
A
S
F
A
N
D
R
E
N
Site 18
Y267
F
A
N
D
R
E
N
Y
D
I
I
K
T
Y
H
Site 19
Y273
N
Y
D
I
I
K
T
Y
H
Y
L
Y
L
A
M
Site 20
Y302
V
L
P
P
I
H
A
Y
G
N
R
T
E
C
R
Site 21
T306
I
H
A
Y
G
N
R
T
E
C
R
N
P
Q
E
Site 22
S344
G
A
D
N
I
D
V
S
H
P
I
I
Y
R
G
Site 23
T381
R
Q
K
G
N
R
N
T
H
K
D
L
L
R
F
Site 24
S421
S
V
L
E
I
E
Q
S
M
N
R
V
K
N
I
Site 25
S429
M
N
R
V
K
N
I
S
D
A
D
V
H
N
A
Site 26
Y440
V
H
N
A
M
D
N
Y
E
C
N
L
Y
T
F
Site 27
T457
L
V
C
I
S
T
K
T
Q
C
S
E
E
D
Q
Site 28
T481
L
I
H
L
D
P
R
T
R
E
G
F
T
L
L
Site 29
T496
H
L
A
V
N
S
N
T
P
V
D
D
F
H
T
Site 30
T503
T
P
V
D
D
F
H
T
N
D
V
C
S
F
P
Site 31
S547
V
Q
Y
N
R
P
I
S
D
F
L
T
L
H
S
Site 32
T569
A
G
A
H
T
D
M
T
N
K
Q
N
K
T
P
Site 33
T575
M
T
N
K
Q
N
K
T
P
L
D
K
S
T
T
Site 34
S580
N
K
T
P
L
D
K
S
T
T
G
V
S
E
I
Site 35
T581
K
T
P
L
D
K
S
T
T
G
V
S
E
I
L
Site 36
Y612
V
R
A
N
D
I
N
Y
Q
D
Q
I
P
R
T
Site 37
T619
Y
Q
D
Q
I
P
R
T
L
E
E
F
V
G
F
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation