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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
FBXO3
Full Name:
Alias:
Type:
Mass (Da):
54561
Number AA:
471
UniProt ID:
Q9UK99
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T12
E
T
E
T
A
P
L
T
L
E
S
L
P
T
D
Site 2
Y38
R
D
L
I
N
C
C
Y
V
S
R
R
L
S
Q
Site 3
S44
C
Y
V
S
R
R
L
S
Q
L
S
S
H
D
P
Site 4
S47
S
R
R
L
S
Q
L
S
S
H
D
P
L
W
R
Site 5
S48
R
R
L
S
Q
L
S
S
H
D
P
L
W
R
R
Site 6
Y60
W
R
R
H
C
K
K
Y
W
L
I
S
E
E
E
Site 7
S64
C
K
K
Y
W
L
I
S
E
E
E
K
T
Q
K
Site 8
T69
L
I
S
E
E
E
K
T
Q
K
N
Q
C
W
K
Site 9
T82
W
K
S
L
F
I
D
T
Y
S
D
V
G
R
Y
Site 10
Y83
K
S
L
F
I
D
T
Y
S
D
V
G
R
Y
I
Site 11
S84
S
L
F
I
D
T
Y
S
D
V
G
R
Y
I
D
Site 12
Y93
V
G
R
Y
I
D
H
Y
A
A
I
K
K
A
W
Site 13
Y106
A
W
D
D
L
K
K
Y
L
E
P
R
C
P
R
Site 14
S117
R
C
P
R
M
V
L
S
L
K
E
G
A
R
E
Site 15
Y142
G
C
K
L
P
D
D
Y
R
C
S
Y
R
I
H
Site 16
Y146
P
D
D
Y
R
C
S
Y
R
I
H
N
G
Q
K
Site 17
S166
L
L
G
S
M
A
L
S
N
H
Y
R
S
E
D
Site 18
T179
E
D
L
L
D
V
D
T
A
A
G
G
F
Q
Q
Site 19
Y192
Q
Q
R
Q
G
L
K
Y
C
L
P
L
T
F
C
Site 20
Y223
R
N
K
N
E
V
F
Y
Q
C
P
D
Q
M
A
Site 21
Y252
F
T
D
W
F
T
S
Y
V
K
N
V
V
S
G
Site 22
Y271
I
R
D
Q
I
F
R
Y
V
H
D
P
E
C
V
Site 23
T280
H
D
P
E
C
V
A
T
T
G
D
I
T
V
S
Site 24
S297
T
S
F
L
P
E
L
S
S
V
H
P
P
H
Y
Site 25
S298
S
F
L
P
E
L
S
S
V
H
P
P
H
Y
F
Site 26
Y304
S
S
V
H
P
P
H
Y
F
F
T
Y
R
I
R
Site 27
Y308
P
P
H
Y
F
F
T
Y
R
I
R
I
E
M
S
Site 28
S315
Y
R
I
R
I
E
M
S
K
D
A
L
P
E
K
Site 29
Y330
A
C
Q
L
D
S
R
Y
W
R
I
T
N
A
K
Site 30
T334
D
S
R
Y
W
R
I
T
N
A
K
G
D
V
E
Site 31
S356
V
G
E
F
P
I
I
S
P
G
R
V
Y
E
Y
Site 32
Y361
I
I
S
P
G
R
V
Y
E
Y
T
S
C
T
T
Site 33
Y363
S
P
G
R
V
Y
E
Y
T
S
C
T
T
F
S
Site 34
T364
P
G
R
V
Y
E
Y
T
S
C
T
T
F
S
T
Site 35
S365
G
R
V
Y
E
Y
T
S
C
T
T
F
S
T
T
Site 36
T368
Y
E
Y
T
S
C
T
T
F
S
T
T
S
G
Y
Site 37
Y379
T
S
G
Y
M
E
G
Y
Y
T
F
H
F
L
Y
Site 38
Y380
S
G
Y
M
E
G
Y
Y
T
F
H
F
L
Y
F
Site 39
Y420
L
E
M
G
P
D
E
Y
E
E
M
E
E
E
E
Site 40
S439
E
E
D
E
D
D
D
S
A
D
M
D
E
S
D
Site 41
S445
D
S
A
D
M
D
E
S
D
E
D
D
E
E
E
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation