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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
FBXL5
Full Name:
Alias:
Type:
Mass (Da):
78555
Number AA:
691
UniProt ID:
Q9UKA1
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T12
P
E
E
V
D
V
F
T
A
P
H
W
R
M
K
Site 2
Y25
M
K
Q
L
V
G
L
Y
C
D
K
L
S
K
T
Site 3
S46
D
F
R
A
L
L
Q
S
L
Y
A
T
F
K
E
Site 4
Y48
R
A
L
L
Q
S
L
Y
A
T
F
K
E
F
K
Site 5
T50
L
L
Q
S
L
Y
A
T
F
K
E
F
K
M
H
Site 6
S73
I
G
L
L
Q
Q
R
S
Q
T
I
Y
N
V
H
Site 7
T75
L
L
Q
Q
R
S
Q
T
I
Y
N
V
H
S
D
Site 8
Y77
Q
Q
R
S
Q
T
I
Y
N
V
H
S
D
N
K
Site 9
S81
Q
T
I
Y
N
V
H
S
D
N
K
L
S
E
M
Site 10
S86
V
H
S
D
N
K
L
S
E
M
L
S
L
F
E
Site 11
S90
N
K
L
S
E
M
L
S
L
F
E
K
G
L
K
Site 12
Y108
N
E
Y
E
Q
L
N
Y
A
K
Q
L
K
E
R
Site 13
T120
K
E
R
L
E
A
F
T
R
D
F
L
P
H
M
Site 14
Y141
F
Q
P
M
L
M
E
Y
F
T
Y
E
E
L
K
Site 15
Y144
M
L
M
E
Y
F
T
Y
E
E
L
K
D
I
K
Site 16
S160
K
V
I
A
Q
H
C
S
Q
K
D
T
A
E
L
Site 17
T164
Q
H
C
S
Q
K
D
T
A
E
L
L
R
G
L
Site 18
S172
A
E
L
L
R
G
L
S
L
W
N
H
A
E
E
Site 19
Y186
E
R
Q
K
F
F
K
Y
S
V
D
E
K
S
D
Site 20
S187
R
Q
K
F
F
K
Y
S
V
D
E
K
S
D
K
Site 21
S192
K
Y
S
V
D
E
K
S
D
K
E
A
E
V
S
Site 22
S199
S
D
K
E
A
E
V
S
E
H
S
T
G
I
T
Site 23
T206
S
E
H
S
T
G
I
T
H
L
P
P
E
V
M
Site 24
S236
S
Q
V
S
M
K
W
S
Q
L
T
K
T
G
S
Site 25
T239
S
M
K
W
S
Q
L
T
K
T
G
S
L
W
K
Site 26
T241
K
W
S
Q
L
T
K
T
G
S
L
W
K
H
L
Site 27
S243
S
Q
L
T
K
T
G
S
L
W
K
H
L
Y
P
Site 28
Y259
H
W
A
R
G
D
W
Y
S
G
P
A
T
E
L
Site 29
S260
W
A
R
G
D
W
Y
S
G
P
A
T
E
L
D
Site 30
T264
D
W
Y
S
G
P
A
T
E
L
D
T
E
P
D
Site 31
T268
G
P
A
T
E
L
D
T
E
P
D
D
E
W
V
Site 32
S297
E
D
A
D
I
D
E
S
E
E
S
A
E
E
S
Site 33
S300
D
I
D
E
S
E
E
S
A
E
E
S
I
A
I
Site 34
S304
S
E
E
S
A
E
E
S
I
A
I
S
I
A
Q
Site 35
S308
A
E
E
S
I
A
I
S
I
A
Q
M
E
K
R
Site 36
T330
N
V
L
P
Y
V
G
T
S
V
K
T
L
V
L
Site 37
T364
N
L
E
H
L
D
L
T
Q
T
D
I
S
D
S
Site 38
T366
E
H
L
D
L
T
Q
T
D
I
S
D
S
A
F
Site 39
S369
D
L
T
Q
T
D
I
S
D
S
A
F
D
S
W
Site 40
S371
T
Q
T
D
I
S
D
S
A
F
D
S
W
S
W
Site 41
S384
S
W
L
G
C
C
Q
S
L
R
H
L
D
L
S
Site 42
S391
S
L
R
H
L
D
L
S
G
C
E
K
I
T
D
Site 43
S416
G
I
L
T
S
H
Q
S
G
F
L
K
T
S
T
Site 44
S422
Q
S
G
F
L
K
T
S
T
S
K
I
T
S
T
Site 45
T423
S
G
F
L
K
T
S
T
S
K
I
T
S
T
A
Site 46
S424
G
F
L
K
T
S
T
S
K
I
T
S
T
A
W
Site 47
S428
T
S
T
S
K
I
T
S
T
A
W
K
N
K
D
Site 48
Y444
T
M
Q
S
T
K
Q
Y
A
C
L
H
D
L
T
Site 49
T451
Y
A
C
L
H
D
L
T
N
K
G
I
G
E
E
Site 50
T466
I
D
N
E
H
P
W
T
K
P
V
S
S
E
N
Site 51
S470
H
P
W
T
K
P
V
S
S
E
N
F
T
S
P
Site 52
S471
P
W
T
K
P
V
S
S
E
N
F
T
S
P
Y
Site 53
T475
P
V
S
S
E
N
F
T
S
P
Y
V
W
M
L
Site 54
S476
V
S
S
E
N
F
T
S
P
Y
V
W
M
L
D
Site 55
Y478
S
E
N
F
T
S
P
Y
V
W
M
L
D
A
E
Site 56
T493
D
L
A
D
I
E
D
T
V
E
W
R
H
R
N
Site 57
S514
M
E
T
A
S
N
F
S
C
S
T
S
G
C
F
Site 58
S516
T
A
S
N
F
S
C
S
T
S
G
C
F
S
K
Site 59
S518
S
N
F
S
C
S
T
S
G
C
F
S
K
D
I
Site 60
T555
H
S
F
C
C
T
G
T
A
L
R
T
M
S
S
Site 61
T559
C
T
G
T
A
L
R
T
M
S
S
L
P
E
S
Site 62
S561
G
T
A
L
R
T
M
S
S
L
P
E
S
S
A
Site 63
S562
T
A
L
R
T
M
S
S
L
P
E
S
S
A
M
Site 64
S566
T
M
S
S
L
P
E
S
S
A
M
C
R
K
A
Site 65
S567
M
S
S
L
P
E
S
S
A
M
C
R
K
A
A
Site 66
T576
M
C
R
K
A
A
R
T
R
L
P
R
G
K
D
Site 67
Y586
P
R
G
K
D
L
I
Y
F
G
S
E
K
S
D
Site 68
S592
I
Y
F
G
S
E
K
S
D
Q
E
T
G
R
V
Site 69
T596
S
E
K
S
D
Q
E
T
G
R
V
L
L
F
L
Site 70
S653
D
L
V
S
A
C
P
S
L
N
D
E
Y
F
Y
Site 71
Y658
C
P
S
L
N
D
E
Y
F
Y
Y
C
D
N
I
Site 72
Y660
S
L
N
D
E
Y
F
Y
Y
C
D
N
I
N
G
Site 73
Y661
L
N
D
E
Y
F
Y
Y
C
D
N
I
N
G
P
Site 74
T672
I
N
G
P
H
A
D
T
A
S
G
C
Q
N
L
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation