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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
Fbxl4
Full Name:
F-box/LRR-repeat protein 4
Alias:
Fbl4; Fbl5; F-box and leucine-rich repeat protein 4; F-box protein FBL4/FBL5
Type:
Mass (Da):
70078
Number AA:
621
UniProt ID:
Q9UKA2
International Prot ID:
IPI00145799
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005737
GO:0005634
GO:0000151
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
GO:0006511
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T25
C
L
R
R
R
A
R
T
A
T
R
G
E
M
M
Site 2
T27
R
R
R
A
R
T
A
T
R
G
E
M
M
N
T
Site 3
T34
T
R
G
E
M
M
N
T
H
R
A
I
E
S
N
Site 4
S40
N
T
H
R
A
I
E
S
N
S
Q
T
S
P
L
Site 5
S42
H
R
A
I
E
S
N
S
Q
T
S
P
L
N
A
Site 6
T44
A
I
E
S
N
S
Q
T
S
P
L
N
A
E
V
Site 7
S45
I
E
S
N
S
Q
T
S
P
L
N
A
E
V
V
Site 8
S62
A
K
E
V
V
D
F
S
S
H
Y
G
S
E
N
Site 9
S63
K
E
V
V
D
F
S
S
H
Y
G
S
E
N
S
Site 10
Y65
V
V
D
F
S
S
H
Y
G
S
E
N
S
M
S
Site 11
S67
D
F
S
S
H
Y
G
S
E
N
S
M
S
Y
T
Site 12
S87
G
V
P
N
V
F
P
S
S
G
D
F
T
Q
T
Site 13
S88
V
P
N
V
F
P
S
S
G
D
F
T
Q
T
A
Site 14
T92
F
P
S
S
G
D
F
T
Q
T
A
V
F
R
T
Site 15
T94
S
S
G
D
F
T
Q
T
A
V
F
R
T
Y
G
Site 16
S111
W
D
Q
C
P
S
A
S
L
P
F
K
R
T
P
Site 17
T117
A
S
L
P
F
K
R
T
P
P
N
F
Q
S
Q
Site 18
S123
R
T
P
P
N
F
Q
S
Q
D
Y
V
E
L
T
Site 19
Y126
P
N
F
Q
S
Q
D
Y
V
E
L
T
F
E
Q
Site 20
T130
S
Q
D
Y
V
E
L
T
F
E
Q
Q
V
Y
P
Site 21
S163
A
C
S
A
N
P
Y
S
P
N
P
P
A
E
V
Site 22
T181
I
L
W
S
E
R
P
T
K
V
N
A
S
Q
A
Site 23
S186
R
P
T
K
V
N
A
S
Q
A
R
Q
F
K
P
Site 24
T202
I
K
Q
I
N
F
P
T
N
L
I
R
L
E
V
Site 25
S212
I
R
L
E
V
N
S
S
L
L
E
Y
Y
T
E
Site 26
S235
V
K
D
K
P
V
L
S
L
K
T
S
L
I
D
Site 27
Y251
N
D
I
E
D
D
A
Y
A
E
K
D
G
C
G
Site 28
S261
K
D
G
C
G
M
D
S
L
N
K
K
F
S
S
Site 29
S267
D
S
L
N
K
K
F
S
S
A
V
L
G
E
G
Site 30
Y279
G
E
G
P
N
N
G
Y
F
D
K
L
P
Y
E
Site 31
Y328
I
H
L
N
L
Q
P
Y
W
A
K
L
D
D
T
Site 32
T335
Y
W
A
K
L
D
D
T
S
L
E
F
L
Q
S
Site 33
S336
W
A
K
L
D
D
T
S
L
E
F
L
Q
S
R
Site 34
S342
T
S
L
E
F
L
Q
S
R
C
T
L
V
Q
W
Site 35
S383
E
L
V
R
L
E
L
S
C
S
H
F
L
N
E
Site 36
S409
N
L
Q
A
L
N
L
S
S
C
D
K
L
P
P
Site 37
Y434
S
L
K
R
L
V
L
Y
R
T
K
V
E
Q
T
Site 38
T493
L
W
R
C
K
N
I
T
E
N
G
I
A
E
L
Site 39
T541
N
L
Q
K
L
F
L
T
A
N
R
S
V
C
D
Site 40
T549
A
N
R
S
V
C
D
T
D
I
D
E
L
A
C
Site 41
T569
Q
Q
L
D
I
L
G
T
R
M
V
S
P
A
S
Site 42
S576
T
R
M
V
S
P
A
S
L
R
K
L
L
E
S
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation