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Updated November 2019
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Protein Info
Short Name:
AKAP11
Full Name:
A-kinase anchor protein 11
Alias:
A kinase anchor protein 220 kDa; AKA11; AKAP 220; AKAP220; A-kinase anchoring protein, 220kDa; PRKA11; Protein kinase A anchoring protein 11; Protein kinase A-anchoring protein 11
Type:
Adaptor/scaffold
Mass (Da):
210512
Number AA:
1901
UniProt ID:
Q9UKA4
International Prot ID:
IPI00007411
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005813
Uniprot
OncoNet
Molecular Function:
GO:0051018
GO:0008157
PhosphoSite+
KinaseNET
Biological Process:
GO:0007243
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S14
N
H
M
K
T
K
A
S
V
R
K
S
F
S
E
Site 2
S18
T
K
A
S
V
R
K
S
F
S
E
D
V
F
Q
Site 3
S20
A
S
V
R
K
S
F
S
E
D
V
F
Q
S
V
Site 4
S26
F
S
E
D
V
F
Q
S
V
K
S
L
L
Q
S
Site 5
S29
D
V
F
Q
S
V
K
S
L
L
Q
S
Q
K
E
Site 6
S33
S
V
K
S
L
L
Q
S
Q
K
E
L
C
S
V
Site 7
S39
Q
S
Q
K
E
L
C
S
V
T
A
E
D
C
L
Site 8
T55
Q
D
E
H
A
N
L
T
E
V
T
F
L
G
F
Site 9
T58
H
A
N
L
T
E
V
T
F
L
G
F
N
E
E
Site 10
S111
I
N
K
P
L
D
I
S
S
D
P
L
N
Q
S
Site 11
S112
N
K
P
L
D
I
S
S
D
P
L
N
Q
S
H
Site 12
S118
S
S
D
P
L
N
Q
S
H
P
S
G
M
L
C
Site 13
S133
V
M
R
V
S
P
T
S
P
R
L
R
I
D
F
Site 14
T150
S
L
L
S
K
Y
A
T
G
I
R
Y
T
L
D
Site 15
T155
Y
A
T
G
I
R
Y
T
L
D
T
F
L
H
Q
Site 16
T158
G
I
R
Y
T
L
D
T
F
L
H
Q
K
H
Q
Site 17
T176
T
D
E
D
D
D
D
T
N
Q
S
V
S
S
I
Site 18
S179
D
D
D
D
T
N
Q
S
V
S
S
I
E
D
D
Site 19
S181
D
D
T
N
Q
S
V
S
S
I
E
D
D
F
V
Site 20
S182
D
T
N
Q
S
V
S
S
I
E
D
D
F
V
T
Site 21
T189
S
I
E
D
D
F
V
T
A
F
E
H
L
E
E
Site 22
T199
E
H
L
E
E
E
E
T
S
K
P
Y
N
D
G
Site 23
S200
H
L
E
E
E
E
T
S
K
P
Y
N
D
G
M
Site 24
S214
M
N
I
T
V
L
R
S
Q
C
D
A
A
S
Q
Site 25
S220
R
S
Q
C
D
A
A
S
Q
T
V
T
G
H
H
Site 26
T222
Q
C
D
A
A
S
Q
T
V
T
G
H
H
L
E
Site 27
T224
D
A
A
S
Q
T
V
T
G
H
H
L
E
T
H
Site 28
S238
H
D
L
K
I
L
I
S
S
G
Q
Q
K
S
L
Site 29
S244
I
S
S
G
Q
Q
K
S
L
A
K
P
S
T
S
Site 30
S249
Q
K
S
L
A
K
P
S
T
S
S
V
N
V
L
Site 31
T250
K
S
L
A
K
P
S
T
S
S
V
N
V
L
G
Site 32
S251
S
L
A
K
P
S
T
S
S
V
N
V
L
G
H
Site 33
S252
L
A
K
P
S
T
S
S
V
N
V
L
G
H
K
Site 34
S263
L
G
H
K
E
L
P
S
V
K
T
S
V
T
T
Site 35
T266
K
E
L
P
S
V
K
T
S
V
T
T
S
I
S
Site 36
S267
E
L
P
S
V
K
T
S
V
T
T
S
I
S
E
Site 37
T269
P
S
V
K
T
S
V
T
T
S
I
S
E
P
W
Site 38
S271
V
K
T
S
V
T
T
S
I
S
E
P
W
T
Q
Site 39
S273
T
S
V
T
T
S
I
S
E
P
W
T
Q
R
S
Site 40
T277
T
S
I
S
E
P
W
T
Q
R
S
F
Y
R
S
Site 41
S280
S
E
P
W
T
Q
R
S
F
Y
R
S
S
N
A
Site 42
Y282
P
W
T
Q
R
S
F
Y
R
S
S
N
A
S
D
Site 43
S284
T
Q
R
S
F
Y
R
S
S
N
A
S
D
K
D
Site 44
S285
Q
R
S
F
Y
R
S
S
N
A
S
D
K
D
S
Site 45
S288
F
Y
R
S
S
N
A
S
D
K
D
S
D
L
Q
Site 46
S292
S
N
A
S
D
K
D
S
D
L
Q
K
T
F
F
Site 47
T297
K
D
S
D
L
Q
K
T
F
F
S
S
S
P
A
Site 48
S300
D
L
Q
K
T
F
F
S
S
S
P
A
Y
S
S
Site 49
S301
L
Q
K
T
F
F
S
S
S
P
A
Y
S
S
E
Site 50
S302
Q
K
T
F
F
S
S
S
P
A
Y
S
S
E
S
Site 51
Y305
F
F
S
S
S
P
A
Y
S
S
E
S
E
C
S
Site 52
S306
F
S
S
S
P
A
Y
S
S
E
S
E
C
S
S
Site 53
S307
S
S
S
P
A
Y
S
S
E
S
E
C
S
S
P
Site 54
S309
S
P
A
Y
S
S
E
S
E
C
S
S
P
S
P
Site 55
S312
Y
S
S
E
S
E
C
S
S
P
S
P
V
I
F
Site 56
S313
S
S
E
S
E
C
S
S
P
S
P
V
I
F
L
Site 57
S315
E
S
E
C
S
S
P
S
P
V
I
F
L
D
E
Site 58
S328
D
E
E
G
Y
Q
K
S
L
K
A
K
L
E
L
Site 59
S348
M
K
D
D
I
E
D
S
D
S
E
V
S
E
F
Site 60
S350
D
D
I
E
D
S
D
S
E
V
S
E
F
F
D
Site 61
S353
E
D
S
D
S
E
V
S
E
F
F
D
S
F
D
Site 62
S358
E
V
S
E
F
F
D
S
F
D
Q
F
D
E
L
Site 63
T368
Q
F
D
E
L
E
Q
T
L
E
T
C
L
F
N
Site 64
S383
K
D
P
V
I
G
K
S
S
Q
R
K
G
H
K
Site 65
S384
D
P
V
I
G
K
S
S
Q
R
K
G
H
K
H
Site 66
T416
P
A
N
V
R
K
P
T
P
R
K
P
E
S
P
Site 67
S422
P
T
P
R
K
P
E
S
P
Y
G
N
L
C
D
Site 68
Y424
P
R
K
P
E
S
P
Y
G
N
L
C
D
A
P
Site 69
S433
E
N
H
D
S
V
Y
Y
T
Y
E
D
Y
A
K
Site 70
S440
S
P
R
P
V
K
A
S
R
E
D
S
G
L
F
Site 71
S444
V
K
A
S
R
E
D
S
G
L
F
S
P
I
R
Site 72
S448
R
E
D
S
G
L
F
S
P
I
R
S
S
A
F
Site 73
S456
P
I
R
S
S
A
F
S
P
L
G
G
C
T
P
Site 74
Y485
H
E
N
H
D
S
V
Y
Y
T
Y
E
D
Y
A
Site 75
Y486
E
N
H
D
S
V
Y
Y
T
Y
E
D
Y
A
K
Site 76
T487
N
H
D
S
V
Y
Y
T
Y
E
D
Y
A
K
S
Site 77
Y488
H
D
S
V
Y
Y
T
Y
E
D
Y
A
K
S
I
Site 78
Y491
V
Y
Y
T
Y
E
D
Y
A
K
S
I
S
C
E
Site 79
S494
T
Y
E
D
Y
A
K
S
I
S
C
E
V
L
G
Site 80
S496
E
D
Y
A
K
S
I
S
C
E
V
L
G
S
V
Site 81
T506
V
L
G
S
V
L
R
T
H
H
T
N
T
L
S
Site 82
T509
S
V
L
R
T
H
H
T
N
T
L
S
N
I
N
Site 83
T511
L
R
T
H
H
T
N
T
L
S
N
I
N
S
I
Site 84
S517
N
T
L
S
N
I
N
S
I
K
H
G
E
N
K
Site 85
T525
I
K
H
G
E
N
K
T
V
T
F
K
H
G
N
Site 86
T527
H
G
E
N
K
T
V
T
F
K
H
G
N
L
D
Site 87
S539
N
L
D
Q
K
N
K
S
K
N
K
S
L
M
I
Site 88
S543
K
N
K
S
K
N
K
S
L
M
I
K
D
S
I
Site 89
S549
K
S
L
M
I
K
D
S
I
Q
K
F
A
A
D
Site 90
S561
A
A
D
L
V
E
K
S
F
G
S
A
F
K
D
Site 91
S574
K
D
L
Q
K
G
V
S
S
C
T
N
A
L
Y
Site 92
S606
L
R
R
Q
R
A
F
S
L
K
E
R
A
I
S
Site 93
S621
G
L
A
N
F
L
V
S
E
A
L
S
N
A
L
Site 94
Y633
N
A
L
K
D
L
Q
Y
V
K
K
Q
I
F
T
Site 95
T642
K
K
Q
I
F
T
N
T
V
A
R
F
A
A
D
Site 96
Y667
M
E
V
C
Q
F
S
Y
P
Q
T
P
A
S
P
Site 97
T670
C
Q
F
S
Y
P
Q
T
P
A
S
P
Q
C
G
Site 98
S673
S
Y
P
Q
T
P
A
S
P
Q
C
G
S
F
D
Site 99
S678
P
A
S
P
Q
C
G
S
F
D
F
E
D
K
V
Site 100
Y689
E
D
K
V
V
K
L
Y
A
K
D
L
S
E
S
Site 101
S694
K
L
Y
A
K
D
L
S
E
S
V
I
Q
E
A
Site 102
S719
F
T
T
K
A
A
V
S
V
S
T
D
N
I
K
Site 103
T741
V
P
S
T
Q
A
V
T
F
S
P
S
F
H
N
Site 104
S743
S
T
Q
A
V
T
F
S
P
S
F
H
N
Q
A
Site 105
T765
Q
E
Y
K
K
E
Y
T
V
Q
Q
A
L
F
C
Site 106
S806
C
Q
A
K
A
H
L
S
S
D
D
S
N
S
N
Site 107
S807
Q
A
K
A
H
L
S
S
D
D
S
N
S
N
G
Site 108
S810
A
H
L
S
S
D
D
S
N
S
N
G
D
S
A
Site 109
S812
L
S
S
D
D
S
N
S
N
G
D
S
A
Q
V
Site 110
S816
D
S
N
S
N
G
D
S
A
Q
V
H
I
A
T
Site 111
S861
N
D
D
I
E
M
Q
S
S
S
K
L
P
N
D
Site 112
S863
D
I
E
M
Q
S
S
S
K
L
P
N
D
P
A
Site 113
S893
E
T
L
E
S
M
T
S
L
E
V
T
K
M
V
Site 114
T897
S
M
T
S
L
E
V
T
K
M
V
D
E
R
T
Site 115
T904
T
K
M
V
D
E
R
T
D
Y
L
T
K
S
L
Site 116
Y906
M
V
D
E
R
T
D
Y
L
T
K
S
L
K
E
Site 117
T908
D
E
R
T
D
Y
L
T
K
S
L
K
E
K
T
Site 118
S910
R
T
D
Y
L
T
K
S
L
K
E
K
T
P
P
Site 119
T915
T
K
S
L
K
E
K
T
P
P
F
S
H
C
D
Site 120
S919
K
E
K
T
P
P
F
S
H
C
D
Q
A
V
L
Site 121
S929
D
Q
A
V
L
Q
C
S
E
A
S
S
N
K
D
Site 122
S933
L
Q
C
S
E
A
S
S
N
K
D
M
F
A
D
Site 123
S943
D
M
F
A
D
R
L
S
K
S
I
I
K
H
S
Site 124
S945
F
A
D
R
L
S
K
S
I
I
K
H
S
I
D
Site 125
S950
S
K
S
I
I
K
H
S
I
D
K
S
K
S
V
Site 126
S954
I
K
H
S
I
D
K
S
K
S
V
I
P
N
I
Site 127
S956
H
S
I
D
K
S
K
S
V
I
P
N
I
D
K
Site 128
Y967
N
I
D
K
N
A
V
Y
K
E
S
L
P
V
S
Site 129
S970
K
N
A
V
Y
K
E
S
L
P
V
S
G
E
E
Site 130
S974
Y
K
E
S
L
P
V
S
G
E
E
S
Q
L
T
Site 131
S978
L
P
V
S
G
E
E
S
Q
L
T
P
E
K
S
Site 132
T981
S
G
E
E
S
Q
L
T
P
E
K
S
P
K
F
Site 133
S985
S
Q
L
T
P
E
K
S
P
K
F
P
D
S
Q
Site 134
S991
K
S
P
K
F
P
D
S
Q
N
Q
L
T
H
C
Site 135
T996
P
D
S
Q
N
Q
L
T
H
C
S
L
S
A
A
Site 136
S999
Q
N
Q
L
T
H
C
S
L
S
A
A
K
D
C
Site 137
S1013
C
V
P
E
C
K
V
S
M
V
H
G
S
S
L
Site 138
S1025
S
S
L
E
T
L
P
S
C
P
A
V
T
G
Q
Site 139
S1034
P
A
V
T
G
Q
K
S
D
L
K
E
S
A
K
Site 140
S1052
L
K
K
H
N
L
N
S
T
S
L
E
A
L
S
Site 141
S1054
K
H
N
L
N
S
T
S
L
E
A
L
S
F
G
Site 142
S1059
S
T
S
L
E
A
L
S
F
G
Q
E
N
P
F
Site 143
S1069
Q
E
N
P
F
P
H
S
H
T
F
S
S
T
A
Site 144
T1071
N
P
F
P
H
S
H
T
F
S
S
T
A
L
T
Site 145
T1100
D
R
N
V
I
P
D
T
P
P
S
T
P
L
V
Site 146
S1103
V
I
P
D
T
P
P
S
T
P
L
V
P
S
R
Site 147
T1104
I
P
D
T
P
P
S
T
P
L
V
P
S
R
A
Site 148
S1109
P
S
T
P
L
V
P
S
R
A
S
S
E
W
D
Site 149
S1112
P
L
V
P
S
R
A
S
S
E
W
D
I
K
K
Site 150
S1113
L
V
P
S
R
A
S
S
E
W
D
I
K
K
L
Site 151
T1136
A
K
E
F
A
P
A
T
P
P
S
T
P
H
N
Site 152
S1139
F
A
P
A
T
P
P
S
T
P
H
N
S
S
V
Site 153
T1140
A
P
A
T
P
P
S
T
P
H
N
S
S
V
G
Site 154
S1144
P
P
S
T
P
H
N
S
S
V
G
S
L
S
E
Site 155
S1145
P
S
T
P
H
N
S
S
V
G
S
L
S
E
N
Site 156
S1148
P
H
N
S
S
V
G
S
L
S
E
N
E
Q
N
Site 157
S1150
N
S
S
V
G
S
L
S
E
N
E
Q
N
T
I
Site 158
S1169
F
M
L
K
L
M
R
S
L
S
E
E
V
E
S
Site 159
S1171
L
K
L
M
R
S
L
S
E
E
V
E
S
S
E
Site 160
S1176
S
L
S
E
E
V
E
S
S
E
S
G
E
L
P
Site 161
S1177
L
S
E
E
V
E
S
S
E
S
G
E
L
P
E
Site 162
S1179
E
E
V
E
S
S
E
S
G
E
L
P
E
V
D
Site 163
S1189
L
P
E
V
D
V
K
S
E
H
S
G
K
K
V
Site 164
S1237
N
P
C
L
N
V
Q
S
Q
R
S
V
S
P
T
Site 165
S1240
L
N
V
Q
S
Q
R
S
V
S
P
T
F
L
N
Site 166
S1242
V
Q
S
Q
R
S
V
S
P
T
F
L
N
P
S
Site 167
T1244
S
Q
R
S
V
S
P
T
F
L
N
P
S
D
E
Site 168
S1249
S
P
T
F
L
N
P
S
D
E
N
L
K
T
L
Site 169
T1255
P
S
D
E
N
L
K
T
L
C
N
F
A
G
D
Site 170
S1289
L
F
K
Q
K
K
N
S
C
Y
A
D
G
D
E
Site 171
Y1291
K
Q
K
K
N
S
C
Y
A
D
G
D
E
D
Y
Site 172
Y1298
Y
A
D
G
D
E
D
Y
K
V
E
E
K
L
D
Site 173
S1329
L
P
P
S
S
C
M
S
G
L
M
Y
K
Y
P
Site 174
Y1333
S
C
M
S
G
L
M
Y
K
Y
P
S
C
E
S
Site 175
Y1335
M
S
G
L
M
Y
K
Y
P
S
C
E
S
V
T
Site 176
S1337
G
L
M
Y
K
Y
P
S
C
E
S
V
T
D
E
Site 177
S1340
Y
K
Y
P
S
C
E
S
V
T
D
E
Y
A
G
Site 178
Y1345
C
E
S
V
T
D
E
Y
A
G
H
L
I
Q
I
Site 179
S1360
L
K
Q
E
G
G
N
S
E
L
I
M
D
Q
Y
Site 180
Y1367
S
E
L
I
M
D
Q
Y
A
N
R
L
A
Y
R
Site 181
Y1373
Q
Y
A
N
R
L
A
Y
R
S
V
K
S
G
L
Site 182
S1375
A
N
R
L
A
Y
R
S
V
K
S
G
L
Q
E
Site 183
S1378
L
A
Y
R
S
V
K
S
G
L
Q
E
A
A
K
Site 184
T1386
G
L
Q
E
A
A
K
T
T
K
V
Q
C
N
S
Site 185
S1401
R
M
F
P
V
P
S
S
Q
V
K
T
N
K
E
Site 186
T1405
V
P
S
S
Q
V
K
T
N
K
E
L
L
M
F
Site 187
S1427
E
A
D
K
K
R
Q
S
K
R
N
E
G
Y
F
Site 188
Y1433
Q
S
K
R
N
E
G
Y
F
C
K
N
Q
T
C
Site 189
Y1447
C
E
R
T
L
D
P
Y
R
N
E
V
S
Q
L
Site 190
S1452
D
P
Y
R
N
E
V
S
Q
L
Y
S
F
S
T
Site 191
Y1455
R
N
E
V
S
Q
L
Y
S
F
S
T
S
L
V
Site 192
S1456
N
E
V
S
Q
L
Y
S
F
S
T
S
L
V
H
Site 193
S1460
Q
L
Y
S
F
S
T
S
L
V
H
S
I
T
K
Site 194
S1464
F
S
T
S
L
V
H
S
I
T
K
D
A
K
E
Site 195
S1476
A
K
E
E
L
T
A
S
L
V
G
L
P
K
S
Site 196
T1485
V
G
L
P
K
S
L
T
D
S
C
L
F
E
K
Site 197
S1487
L
P
K
S
L
T
D
S
C
L
F
E
K
S
G
Site 198
S1493
D
S
C
L
F
E
K
S
G
Y
E
E
D
N
E
Site 199
Y1495
C
L
F
E
K
S
G
Y
E
E
D
N
E
C
H
Site 200
T1504
E
D
N
E
C
H
V
T
P
E
L
P
K
S
L
Site 201
S1510
V
T
P
E
L
P
K
S
L
Q
P
S
S
Q
N
Site 202
S1514
L
P
K
S
L
Q
P
S
S
Q
N
H
R
F
Y
Site 203
S1515
P
K
S
L
Q
P
S
S
Q
N
H
R
F
Y
H
Site 204
Y1521
S
S
Q
N
H
R
F
Y
H
S
T
G
S
L
N
Site 205
S1523
Q
N
H
R
F
Y
H
S
T
G
S
L
N
G
Y
Site 206
T1524
N
H
R
F
Y
H
S
T
G
S
L
N
G
Y
G
Site 207
S1526
R
F
Y
H
S
T
G
S
L
N
G
Y
G
C
G
Site 208
Y1530
S
T
G
S
L
N
G
Y
G
C
G
D
N
V
V
Site 209
T1551
A
K
K
V
V
D
D
T
L
E
L
T
L
G
S
Site 210
S1564
G
S
T
V
F
R
V
S
E
T
T
K
S
A
D
Site 211
S1569
R
V
S
E
T
T
K
S
A
D
R
V
T
Y
A
Site 212
T1574
T
K
S
A
D
R
V
T
Y
A
E
K
L
S
P
Site 213
Y1575
K
S
A
D
R
V
T
Y
A
E
K
L
S
P
L
Site 214
S1580
V
T
Y
A
E
K
L
S
P
L
T
G
Q
A
C
Site 215
T1583
A
E
K
L
S
P
L
T
G
Q
A
C
R
Y
C
Site 216
Y1589
L
T
G
Q
A
C
R
Y
C
D
L
K
E
L
H
Site 217
T1599
L
K
E
L
H
N
C
T
G
N
S
S
Q
H
F
Site 218
S1611
Q
H
F
F
R
Q
G
S
L
A
S
S
K
P
A
Site 219
S1614
F
R
Q
G
S
L
A
S
S
K
P
A
S
N
P
Site 220
S1615
R
Q
G
S
L
A
S
S
K
P
A
S
N
P
K
Site 221
S1619
L
A
S
S
K
P
A
S
N
P
K
F
S
S
R
Site 222
S1624
P
A
S
N
P
K
F
S
S
R
Y
Q
K
S
R
Site 223
S1625
A
S
N
P
K
F
S
S
R
Y
Q
K
S
R
I
Site 224
S1630
F
S
S
R
Y
Q
K
S
R
I
F
H
L
S
V
Site 225
S1636
K
S
R
I
F
H
L
S
V
P
Q
I
H
V
N
Site 226
S1667
E
K
A
E
R
E
L
S
S
T
S
L
A
A
D
Site 227
T1669
A
E
R
E
L
S
S
T
S
L
A
A
D
S
G
Site 228
S1670
E
R
E
L
S
S
T
S
L
A
A
D
S
G
I
Site 229
S1675
S
T
S
L
A
A
D
S
G
I
G
Q
E
G
A
Site 230
S1687
E
G
A
S
F
A
E
S
L
A
T
E
T
M
T
Site 231
S1705
T
N
V
G
H
A
V
S
S
S
K
E
I
E
D
Site 232
S1707
V
G
H
A
V
S
S
S
K
E
I
E
D
F
Q
Site 233
S1715
K
E
I
E
D
F
Q
S
T
E
S
V
S
S
Q
Site 234
T1716
E
I
E
D
F
Q
S
T
E
S
V
S
S
Q
Q
Site 235
S1718
E
D
F
Q
S
T
E
S
V
S
S
Q
Q
M
N
Site 236
S1721
Q
S
T
E
S
V
S
S
Q
Q
M
N
L
S
I
Site 237
S1727
S
S
Q
Q
M
N
L
S
I
G
D
D
S
T
G
Site 238
S1732
N
L
S
I
G
D
D
S
T
G
S
W
S
N
L
Site 239
T1733
L
S
I
G
D
D
S
T
G
S
W
S
N
L
S
Site 240
S1735
I
G
D
D
S
T
G
S
W
S
N
L
S
F
E
Site 241
S1737
D
D
S
T
G
S
W
S
N
L
S
F
E
D
E
Site 242
S1740
T
G
S
W
S
N
L
S
F
E
D
E
H
Q
D
Site 243
S1751
E
H
Q
D
E
S
S
S
F
H
H
L
S
E
S
Site 244
S1756
S
S
S
F
H
H
L
S
E
S
N
G
N
S
S
Site 245
S1758
S
F
H
H
L
S
E
S
N
G
N
S
S
S
W
Site 246
S1762
L
S
E
S
N
G
N
S
S
S
W
S
S
L
G
Site 247
S1763
S
E
S
N
G
N
S
S
S
W
S
S
L
G
L
Site 248
S1764
E
S
N
G
N
S
S
S
W
S
S
L
G
L
E
Site 249
S1766
N
G
N
S
S
S
W
S
S
L
G
L
E
G
D
Site 250
S1767
G
N
S
S
S
W
S
S
L
G
L
E
G
D
L
Site 251
Y1775
L
G
L
E
G
D
L
Y
E
D
N
L
S
F
P
Site 252
S1780
D
L
Y
E
D
N
L
S
F
P
T
S
D
S
D
Site 253
S1784
D
N
L
S
F
P
T
S
D
S
D
G
P
D
D
Site 254
S1786
L
S
F
P
T
S
D
S
D
G
P
D
D
K
D
Site 255
T1809
G
L
G
Q
D
G
K
T
L
L
I
T
N
I
D
Site 256
T1821
N
I
D
M
E
P
C
T
V
D
P
Q
L
R
I
Site 257
Y1844
E
A
E
V
A
E
L
Y
F
H
D
S
A
N
K
Site 258
Y1878
L
Q
A
V
L
Q
Y
Y
E
V
M
E
K
A
S
Site 259
S1886
E
V
M
E
K
A
S
S
E
E
R
C
K
S
L
Site 260
S1892
S
S
E
E
R
C
K
S
L
F
D
W
L
L
E
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation