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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
PTBP2
Full Name:
Polypyrimidine tract-binding protein 2
Alias:
BrPTB; Neural polypyrimidine tract-binding protein; Neurally-enriched homolog of PTB; Non-neuronal splice variant nPTB3; NPTB; Polypyrimidine tract binding protein 2; PTB; PTB-like protein; PTBLP
Type:
RNA processing
Mass (Da):
57491
Number AA:
531
UniProt ID:
Q9UKA9
International Prot ID:
IPI00514064
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005634
Uniprot
OncoNet
Molecular Function:
GO:0003723
GO:0000166
PhosphoSite+
KinaseNET
Biological Process:
GO:0008380
GO:0006397
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S16
A
V
G
V
K
R
G
S
D
E
L
L
S
G
S
Site 2
S21
R
G
S
D
E
L
L
S
G
S
V
L
S
S
P
Site 3
S23
S
D
E
L
L
S
G
S
V
L
S
S
P
N
S
Site 4
S26
L
L
S
G
S
V
L
S
S
P
N
S
N
M
S
Site 5
S27
L
S
G
S
V
L
S
S
P
N
S
N
M
S
S
Site 6
S33
S
S
P
N
S
N
M
S
S
M
V
V
T
A
N
Site 7
S34
S
P
N
S
N
M
S
S
M
V
V
T
A
N
G
Site 8
T38
N
M
S
S
M
V
V
T
A
N
G
N
D
S
K
Site 9
S44
V
T
A
N
G
N
D
S
K
K
F
K
G
E
D
Site 10
T118
V
N
Y
Y
S
A
V
T
P
H
L
R
N
Q
P
Site 11
Y127
H
L
R
N
Q
P
I
Y
I
Q
Y
S
N
H
K
Site 12
T138
S
N
H
K
E
L
K
T
D
N
T
L
N
Q
R
Site 13
T141
K
E
L
K
T
D
N
T
L
N
Q
R
A
Q
A
Site 14
S164
Q
T
A
N
T
P
L
S
G
T
T
V
S
E
S
Site 15
T167
N
T
P
L
S
G
T
T
V
S
E
S
A
V
T
Site 16
Y225
Q
F
Q
A
L
L
Q
Y
G
D
P
V
N
A
Q
Site 17
Y244
A
L
D
G
Q
N
I
Y
N
A
C
C
T
L
R
Site 18
Y264
L
V
N
L
N
V
K
Y
N
N
D
K
S
R
D
Site 19
S269
V
K
Y
N
N
D
K
S
R
D
Y
T
R
P
D
Site 20
Y272
N
N
D
K
S
R
D
Y
T
R
P
D
L
P
S
Site 21
T273
N
D
K
S
R
D
Y
T
R
P
D
L
P
S
G
Site 22
S279
Y
T
R
P
D
L
P
S
G
D
G
Q
P
A
L
Site 23
S308
L
A
V
P
G
A
L
S
P
L
A
I
P
N
A
Site 24
T351
N
L
N
E
E
M
V
T
P
Q
S
L
F
T
L
Site 25
Y372
V
Q
R
V
K
I
L
Y
N
K
K
D
S
A
L
Site 26
T408
Y
G
K
I
I
R
V
T
L
S
K
H
Q
T
V
Site 27
T414
V
T
L
S
K
H
Q
T
V
Q
L
P
R
E
G
Site 28
S434
L
T
K
D
F
G
N
S
P
L
H
R
F
K
K
Site 29
S444
H
R
F
K
K
P
G
S
K
N
F
Q
N
I
F
Site 30
S454
F
Q
N
I
F
P
P
S
A
T
L
H
L
S
N
Site 31
S465
H
L
S
N
I
P
P
S
V
A
E
E
D
L
R
Site 32
T473
V
A
E
E
D
L
R
T
L
F
A
N
T
G
G
Site 33
Y514
A
L
I
D
L
H
N
Y
N
L
G
E
N
H
H
Site 34
S525
E
N
H
H
L
R
V
S
F
S
K
S
T
I
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation