PhosphoNET

           
Protein Info 
   
Short Name:  Cdc42EP3
Full Name:  Cdc42 effector protein 3
Alias:  Binder of Rho GTPases 2; BORG2; CDC42 effector protein (Rho GTPase binding) 3; CDC42EP3; CEP3; MSE55-related Cdc42-binding protein; UB1
Type:  G protein regulator, misc.
Mass (Da):  27678
Number AA:  254
UniProt ID:  Q9UKI2
International Prot ID:  IPI00294391
Sequence:  Retrieve full protein sequence
   
GO Terms  External Links Internal Links  
   
Cellular Component:  GO:0015629  GO:0005737  GO:0019898 Uniprot OncoNet
Molecular Function:  GO:0005519     PhosphoSite+ KinaseNET
Biological Process:  GO:0008360  GO:0007165   Phosida TranscriptoNet
    STRING Kinexus Products
   
Info Box  A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites 
-7-6-5-4-3-2-101234567Expt. conf.EffectKinasePPaseKinexus ProductsRef.Evol.Kinase Pred.P-site Match
Site 1Y8MPAKTPIYLKAANNK
Site 2S27FKLRDILSPDMISPP
Site 3T41PLGDFRHTIHIGKEG
Site 4Y63ISFLQGNYELLPGNQ
Site 5S89NEFFRANSTSDSVFT
Site 6T90EFFRANSTSDSVFTE
Site 7S91FFRANSTSDSVFTET
Site 8S93RANSTSDSVFTETPS
Site 9T96STSDSVFTETPSPVL
Site 10T98SDSVFTETPSPVLKN
Site 11S100SVFTETPSPVLKNAI
Site 12S108PVLKNAISLPTIGGS
Site 13T127LPLLSPVTFNSKQES
Site 14S130LSPVTFNSKQESFGP
Site 15S134TFNSKQESFGPAKLP
Site 16S144PAKLPRLSCEPVMEE
Site 17T170GTVHQGDTSWGSSGS
Site 18S171TVHQGDTSWGSSGSA
Site 19S174QGDTSWGSSGSASQS
Site 20S175GDTSWGSSGSASQSS
Site 21S177TSWGSSGSASQSSQG
Site 22S179WGSSGSASQSSQGRD
Site 23S181SSGSASQSSQGRDSH
Site 24S182SGSASQSSQGRDSHS
Site 25S187QSSQGRDSHSSSLSE
Site 26S189SQGRDSHSSSLSEQY
Site 27S190QGRDSHSSSLSEQYP
Site 28S191GRDSHSSSLSEQYPD
Site 29S193DSHSSSLSEQYPDWP
Site 30Y196SSSLSEQYPDWPAED
Site 31T209EDMFDHPTPCELIKG
Site 32T218CELIKGKTKSEESLS
Site 33S220LIKGKTKSEESLSDL
Site 34S223GKTKSEESLSDLTGS
Site 35S225TKSEESLSDLTGSLL
Site 36T228EESLSDLTGSLLSLQ
 
Legend 
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available  
Products available
 


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