KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
DrugProNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
Home
|
Kinexus
|
Contact
|
Credits
Protein Info
Short Name:
ADAM28
Full Name:
Alias:
Type:
Mass (Da):
87181
Number AA:
775
UniProt ID:
Q9UKQ2
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
Y28
E
L
P
G
V
K
K
Y
E
V
V
Y
P
I
R
Site 2
Y32
V
K
K
Y
E
V
V
Y
P
I
R
L
H
P
L
Site 3
T55
E
Q
Q
E
Q
F
E
T
E
L
K
Y
K
M
T
Site 4
Y59
Q
F
E
T
E
L
K
Y
K
M
T
I
N
G
K
Site 5
Y71
N
G
K
I
A
V
L
Y
L
K
K
N
K
N
L
Site 6
Y83
K
N
L
L
A
P
G
Y
T
E
T
Y
Y
N
S
Site 7
T86
L
A
P
G
Y
T
E
T
Y
Y
N
S
T
G
K
Site 8
Y87
A
P
G
Y
T
E
T
Y
Y
N
S
T
G
K
E
Site 9
Y88
P
G
Y
T
E
T
Y
Y
N
S
T
G
K
E
I
Site 10
S98
T
G
K
E
I
T
T
S
P
Q
I
M
D
D
C
Site 11
Y107
Q
I
M
D
D
C
Y
Y
Q
G
H
I
L
N
E
Site 12
S117
H
I
L
N
E
K
V
S
D
A
S
I
S
T
C
Site 13
S122
K
V
S
D
A
S
I
S
T
C
R
G
L
R
G
Site 14
T123
V
S
D
A
S
I
S
T
C
R
G
L
R
G
Y
Site 15
Y130
T
C
R
G
L
R
G
Y
F
S
Q
G
D
Q
R
Site 16
S132
R
G
L
R
G
Y
F
S
Q
G
D
Q
R
Y
F
Site 17
Y138
F
S
Q
G
D
Q
R
Y
F
I
E
P
L
S
P
Site 18
S144
R
Y
F
I
E
P
L
S
P
I
H
R
D
G
Q
Site 19
Y158
Q
E
H
A
L
F
K
Y
N
P
D
E
K
N
Y
Site 20
Y165
Y
N
P
D
E
K
N
Y
D
S
T
C
G
M
D
Site 21
S167
P
D
E
K
N
Y
D
S
T
C
G
M
D
G
V
Site 22
T168
D
E
K
N
Y
D
S
T
C
G
M
D
G
V
L
Site 23
Y237
R
V
F
E
M
A
N
Y
V
N
M
L
Y
K
K
Site 24
S690
A
M
V
I
R
H
Q
S
S
R
E
K
Q
K
K
Site 25
S703
K
K
D
Q
R
P
L
S
T
T
G
T
R
P
H
Site 26
T705
D
Q
R
P
L
S
T
T
G
T
R
P
H
K
Q
Site 27
T707
R
P
L
S
T
T
G
T
R
P
H
K
Q
K
R
Site 28
Y735
S
Q
M
K
P
H
V
Y
D
L
P
V
E
G
N
Site 29
S747
E
G
N
E
P
P
A
S
F
H
K
D
T
N
A
Site 30
T752
P
A
S
F
H
K
D
T
N
A
L
P
P
T
V
Site 31
T758
D
T
N
A
L
P
P
T
V
F
K
D
N
P
M
Site 32
S766
V
F
K
D
N
P
M
S
T
P
K
D
S
N
P
Site 33
T767
F
K
D
N
P
M
S
T
P
K
D
S
N
P
E
Site 34
S771
P
M
S
T
P
K
D
S
N
P
E
A
_
_
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation