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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
IKZF3
Full Name:
Zinc finger protein Aiolos
Alias:
AIOL; Aiolos; IKAROS family zinc finger 3; Zinc finger protein Aiolos; ZNFN1A3
Type:
Transcription factor
Mass (Da):
58023
Number AA:
509
UniProt ID:
Q9UKT9
International Prot ID:
IPI00018923
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005634
Uniprot
OncoNet
Molecular Function:
GO:0003700
GO:0008270
PhosphoSite+
KinaseNET
Biological Process:
GO:0007498
GO:0006357
GO:0006350
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T6
_
_
M
E
D
I
Q
T
N
A
E
L
K
S
T
Site 2
S12
Q
T
N
A
E
L
K
S
T
Q
E
Q
S
V
P
Site 3
T13
T
N
A
E
L
K
S
T
Q
E
Q
S
V
P
A
Site 4
S17
L
K
S
T
Q
E
Q
S
V
P
A
E
S
A
A
Site 5
S22
E
Q
S
V
P
A
E
S
A
A
V
L
N
D
Y
Site 6
Y29
S
A
A
V
L
N
D
Y
S
L
T
K
S
H
E
Site 7
S30
A
A
V
L
N
D
Y
S
L
T
K
S
H
E
M
Site 8
S34
N
D
Y
S
L
T
K
S
H
E
M
E
N
V
D
Site 9
S42
H
E
M
E
N
V
D
S
G
E
G
P
A
N
E
Site 10
S57
D
E
D
I
G
D
D
S
M
K
V
K
D
E
Y
Site 11
Y64
S
M
K
V
K
D
E
Y
S
E
R
D
E
N
V
Site 12
S65
M
K
V
K
D
E
Y
S
E
R
D
E
N
V
L
Site 13
S74
R
D
E
N
V
L
K
S
E
P
M
G
N
A
E
Site 14
S88
E
E
P
E
I
P
Y
S
Y
S
R
E
Y
N
E
Site 15
Y89
E
P
E
I
P
Y
S
Y
S
R
E
Y
N
E
Y
Site 16
S90
P
E
I
P
Y
S
Y
S
R
E
Y
N
E
Y
E
Site 17
Y93
P
Y
S
Y
S
R
E
Y
N
E
Y
E
N
I
K
Site 18
Y96
Y
S
R
E
Y
N
E
Y
E
N
I
K
L
E
R
Site 19
S107
K
L
E
R
H
V
V
S
F
D
S
S
R
P
T
Site 20
S110
R
H
V
V
S
F
D
S
S
R
P
T
S
G
K
Site 21
S111
H
V
V
S
F
D
S
S
R
P
T
S
G
K
M
Site 22
T114
S
F
D
S
S
R
P
T
S
G
K
M
N
C
D
Site 23
S115
F
D
S
S
R
P
T
S
G
K
M
N
C
D
V
Site 24
T141
M
V
H
K
R
S
H
T
G
E
R
P
F
Q
C
Site 25
T169
L
R
H
I
K
L
H
T
G
E
K
P
F
K
C
Site 26
T190
C
Q
R
R
D
A
L
T
G
H
L
R
T
H
S
Site 27
S197
T
G
H
L
R
T
H
S
V
E
K
P
Y
K
C
Site 28
Y202
T
H
S
V
E
K
P
Y
K
C
E
F
C
G
R
Site 29
Y211
C
E
F
C
G
R
S
Y
K
Q
R
S
S
L
E
Site 30
S216
R
S
Y
K
Q
R
S
S
L
E
E
H
K
E
R
Site 31
T226
E
H
K
E
R
C
R
T
F
L
Q
S
T
D
P
Site 32
S230
R
C
R
T
F
L
Q
S
T
D
P
G
D
T
A
Site 33
S238
T
D
P
G
D
T
A
S
A
E
A
R
H
I
K
Site 34
S250
H
I
K
A
E
M
G
S
E
R
A
L
V
L
D
Site 35
S261
L
V
L
D
R
L
A
S
N
V
A
K
R
K
S
Site 36
S268
S
N
V
A
K
R
K
S
S
M
P
Q
K
F
I
Site 37
S269
N
V
A
K
R
K
S
S
M
P
Q
K
F
I
G
Site 38
Y286
R
H
C
F
D
V
N
Y
N
S
S
Y
M
Y
E
Site 39
Y290
D
V
N
Y
N
S
S
Y
M
Y
E
K
E
S
E
Site 40
Y292
N
Y
N
S
S
Y
M
Y
E
K
E
S
E
L
I
Site 41
T301
K
E
S
E
L
I
Q
T
R
M
M
D
Q
A
I
Site 42
T326
A
L
R
P
L
V
Q
T
P
P
A
P
T
S
E
Site 43
S332
Q
T
P
P
A
P
T
S
E
M
V
P
V
I
S
Site 44
T347
S
M
Y
P
I
A
L
T
R
A
E
M
S
N
G
Site 45
S370
S
I
H
L
P
E
K
S
V
P
S
E
R
G
L
Site 46
S373
L
P
E
K
S
V
P
S
E
R
G
L
S
P
N
Site 47
S378
V
P
S
E
R
G
L
S
P
N
N
S
G
H
D
Site 48
S382
R
G
L
S
P
N
N
S
G
H
D
S
T
D
T
Site 49
S386
P
N
N
S
G
H
D
S
T
D
T
D
S
N
H
Site 50
T387
N
N
S
G
H
D
S
T
D
T
D
S
N
H
E
Site 51
T389
S
G
H
D
S
T
D
T
D
S
N
H
E
E
R
Site 52
S391
H
D
S
T
D
T
D
S
N
H
E
E
R
Q
N
Site 53
Y401
E
E
R
Q
N
H
I
Y
Q
Q
N
H
M
V
L
Site 54
S424
L
L
K
E
V
P
R
S
Y
E
L
L
K
P
P
Site 55
Y425
L
K
E
V
P
R
S
Y
E
L
L
K
P
P
P
Site 56
S438
P
P
I
C
P
R
D
S
V
K
V
I
N
K
E
Site 57
Y452
E
G
E
V
M
D
V
Y
R
C
D
H
C
R
V
Site 58
Y493
G
Y
R
S
H
D
R
Y
E
F
S
S
H
I
A
Site 59
S497
H
D
R
Y
E
F
S
S
H
I
A
R
G
E
H
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation