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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
ACSL6
Full Name:
Long-chain-fatty-acid--CoA ligase 6
Alias:
Type:
Mass (Da):
77752
Number AA:
697
UniProt ID:
Q9UKU0
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S67
Q
S
E
E
V
E
D
S
G
G
A
R
R
S
V
Site 2
S73
D
S
G
G
A
R
R
S
V
I
G
S
G
P
Q
Site 3
S77
A
R
R
S
V
I
G
S
G
P
Q
L
L
T
H
Site 4
T83
G
S
G
P
Q
L
L
T
H
Y
Y
D
D
A
R
Site 5
Y85
G
P
Q
L
L
T
H
Y
Y
D
D
A
R
T
M
Site 6
Y86
P
Q
L
L
T
H
Y
Y
D
D
A
R
T
M
Y
Site 7
Y93
Y
D
D
A
R
T
M
Y
Q
V
F
R
R
G
L
Site 8
S101
Q
V
F
R
R
G
L
S
I
S
G
N
G
P
C
Site 9
S103
F
R
R
G
L
S
I
S
G
N
G
P
C
L
G
Site 10
Y118
F
R
K
P
K
Q
P
Y
Q
W
L
S
Y
Q
E
Site 11
S122
K
Q
P
Y
Q
W
L
S
Y
Q
E
V
A
D
R
Site 12
S135
D
R
A
E
F
L
G
S
G
L
L
Q
H
N
C
Site 13
T192
A
I
R
Y
I
I
N
T
A
D
I
S
T
V
I
Site 14
S196
I
I
N
T
A
D
I
S
T
V
I
V
D
K
P
Site 15
T197
I
N
T
A
D
I
S
T
V
I
V
D
K
P
Q
Site 16
T218
E
H
V
E
R
K
E
T
P
G
L
K
L
I
I
Site 17
S271
P
P
Q
P
D
D
L
S
I
V
C
F
T
S
G
Site 18
S352
Q
G
D
I
R
L
L
S
D
D
M
K
A
L
C
Site 19
Y374
P
R
L
L
N
R
M
Y
D
K
I
F
S
Q
A
Site 20
S379
R
M
Y
D
K
I
F
S
Q
A
N
T
P
L
K
Site 21
T383
K
I
F
S
Q
A
N
T
P
L
K
R
W
L
L
Site 22
S410
S
G
I
I
R
N
D
S
I
W
D
E
L
F
F
Site 23
S439
V
T
G
A
A
P
A
S
P
T
V
L
G
F
L
Site 24
Y455
A
A
L
G
C
Q
V
Y
E
G
Y
G
Q
T
E
Site 25
T471
T
A
G
C
T
F
T
T
P
G
D
W
T
S
G
Site 26
S477
T
T
P
G
D
W
T
S
G
H
V
G
A
P
L
Site 27
Y499
V
D
V
E
E
L
N
Y
W
A
C
K
G
E
G
Site 28
S532
R
T
K
E
A
L
D
S
D
G
W
L
H
T
G
Site 29
T549
G
K
W
L
P
A
G
T
L
K
I
I
D
R
K
Site 30
Y567
F
K
L
A
Q
G
E
Y
V
A
P
E
K
I
E
Site 31
Y577
P
E
K
I
E
N
I
Y
I
R
S
Q
P
V
A
Site 32
Y587
S
Q
P
V
A
Q
I
Y
V
H
G
D
S
L
K
Site 33
S610
P
D
P
E
V
M
P
S
W
A
Q
K
R
G
I
Site 34
T620
Q
K
R
G
I
E
G
T
Y
A
D
L
C
T
N
Site 35
Y621
K
R
G
I
E
G
T
Y
A
D
L
C
T
N
K
Site 36
S645
M
V
R
L
G
K
E
S
G
L
H
S
F
E
Q
Site 37
S649
G
K
E
S
G
L
H
S
F
E
Q
V
K
A
I
Site 38
S664
H
I
H
S
D
M
F
S
V
Q
N
G
L
L
T
Site 39
T671
S
V
Q
N
G
L
L
T
P
T
L
K
A
K
R
Site 40
Y684
K
R
P
E
L
R
E
Y
F
K
K
Q
I
E
E
Site 41
Y693
K
K
Q
I
E
E
L
Y
S
I
S
M
_
_
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation