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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
NUP50
Full Name:
Nuclear pore complex protein Nup50
Alias:
NPAP60; NPAP60L; Nuclear pore-associated protein 60 kDa-like; Nucleoporin 50kDa
Type:
Nucleoporin
Mass (Da):
50144
Number AA:
468
UniProt ID:
Q9UKX7
International Prot ID:
IPI00026940
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005643
GO:0005654
Uniprot
OncoNet
Molecular Function:
GO:0005515
PhosphoSite+
KinaseNET
Biological Process:
GO:0046907
GO:0051028
GO:0015031
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T11
R
N
A
E
K
E
L
T
D
R
N
W
D
Q
E
Site 2
T26
D
E
A
E
E
V
G
T
F
S
M
A
S
E
E
Site 3
S52
R
R
N
V
G
F
E
S
D
T
G
G
A
F
K
Site 4
T54
N
V
G
F
E
S
D
T
G
G
A
F
K
G
F
Site 5
S68
F
K
G
L
V
V
P
S
G
G
G
R
F
S
G
Site 6
S74
P
S
G
G
G
R
F
S
G
F
G
S
G
A
G
Site 7
S78
G
R
F
S
G
F
G
S
G
A
G
G
K
P
L
Site 8
S89
G
K
P
L
E
G
L
S
N
G
N
N
I
T
S
Site 9
S96
S
N
G
N
N
I
T
S
A
P
P
F
A
S
A
Site 10
S115
D
P
K
V
A
F
G
S
L
A
A
N
G
P
T
Site 11
T122
S
L
A
A
N
G
P
T
T
L
V
D
K
V
S
Site 12
T123
L
A
A
N
G
P
T
T
L
V
D
K
V
S
N
Site 13
S129
T
T
L
V
D
K
V
S
N
P
K
T
N
G
D
Site 14
T133
D
K
V
S
N
P
K
T
N
G
D
S
Q
Q
P
Site 15
S137
N
P
K
T
N
G
D
S
Q
Q
P
S
S
S
G
Site 16
S141
N
G
D
S
Q
Q
P
S
S
S
G
L
A
S
S
Site 17
S142
G
D
S
Q
Q
P
S
S
S
G
L
A
S
S
K
Site 18
S143
D
S
Q
Q
P
S
S
S
G
L
A
S
S
K
A
Site 19
S147
P
S
S
S
G
L
A
S
S
K
A
C
V
G
N
Site 20
S148
S
S
S
G
L
A
S
S
K
A
C
V
G
N
A
Site 21
T184
T
N
P
L
C
D
L
T
P
I
F
K
D
Y
E
Site 22
Y190
L
T
P
I
F
K
D
Y
E
K
Y
L
A
N
I
Site 23
Y193
I
F
K
D
Y
E
K
Y
L
A
N
I
E
Q
Q
Site 24
S204
I
E
Q
Q
H
G
N
S
G
R
N
S
E
S
E
Site 25
S208
H
G
N
S
G
R
N
S
E
S
E
S
N
K
V
Site 26
S210
N
S
G
R
N
S
E
S
E
S
N
K
V
A
A
Site 27
S212
G
R
N
S
E
S
E
S
N
K
V
A
A
E
T
Site 28
T219
S
N
K
V
A
A
E
T
Q
S
P
S
L
F
G
Site 29
S221
K
V
A
A
E
T
Q
S
P
S
L
F
G
S
T
Site 30
S223
A
A
E
T
Q
S
P
S
L
F
G
S
T
K
L
Site 31
S227
Q
S
P
S
L
F
G
S
T
K
L
Q
Q
E
S
Site 32
T228
S
P
S
L
F
G
S
T
K
L
Q
Q
E
S
T
Site 33
S234
S
T
K
L
Q
Q
E
S
T
F
L
F
H
G
N
Site 34
T235
T
K
L
Q
Q
E
S
T
F
L
F
H
G
N
K
Site 35
T246
H
G
N
K
T
E
D
T
P
D
K
K
M
E
V
Site 36
T259
E
V
A
S
E
K
K
T
D
P
S
S
L
G
A
Site 37
S263
E
K
K
T
D
P
S
S
L
G
A
T
S
A
S
Site 38
T267
D
P
S
S
L
G
A
T
S
A
S
F
N
F
G
Site 39
S268
P
S
S
L
G
A
T
S
A
S
F
N
F
G
K
Site 40
S270
S
L
G
A
T
S
A
S
F
N
F
G
K
K
V
Site 41
S279
N
F
G
K
K
V
D
S
S
V
L
G
S
L
S
Site 42
S280
F
G
K
K
V
D
S
S
V
L
G
S
L
S
S
Site 43
T291
S
L
S
S
V
P
L
T
G
F
S
F
S
P
G
Site 44
S294
S
V
P
L
T
G
F
S
F
S
P
G
N
S
S
Site 45
S296
P
L
T
G
F
S
F
S
P
G
N
S
S
L
F
Site 46
S300
F
S
F
S
P
G
N
S
S
L
F
G
K
D
T
Site 47
S301
S
F
S
P
G
N
S
S
L
F
G
K
D
T
T
Site 48
T307
S
S
L
F
G
K
D
T
T
Q
S
K
P
V
S
Site 49
T308
S
L
F
G
K
D
T
T
Q
S
K
P
V
S
S
Site 50
S310
F
G
K
D
T
T
Q
S
K
P
V
S
S
P
F
Site 51
S314
T
T
Q
S
K
P
V
S
S
P
F
P
T
K
P
Site 52
S315
T
Q
S
K
P
V
S
S
P
F
P
T
K
P
L
Site 53
T319
P
V
S
S
P
F
P
T
K
P
L
E
G
Q
A
Site 54
S330
E
G
Q
A
E
G
D
S
G
E
C
K
G
G
D
Site 55
Y359
V
K
E
E
D
A
F
Y
S
K
K
C
K
L
F
Site 56
Y367
S
K
K
C
K
L
F
Y
K
K
D
N
E
F
K
Site 57
T417
I
P
P
N
M
P
C
T
R
T
G
K
N
N
V
Site 58
T451
T
M
L
I
R
V
K
T
S
E
D
A
D
E
L
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation