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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
ZHX1
Full Name:
Zinc fingers and homeoboxes protein 1
Alias:
Zinc fingers and homeoboxes 1
Type:
Uncharacterized protein
Mass (Da):
98098
Number AA:
873
UniProt ID:
Q9UKY1
International Prot ID:
IPI00293086
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005634
Uniprot
OncoNet
Molecular Function:
GO:0005515
GO:0043565
GO:0003700
PhosphoSite+
KinaseNET
Biological Process:
GO:0045892
GO:0006350
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S7
_
M
A
S
R
R
K
S
T
T
P
C
M
V
L
Site 2
T8
M
A
S
R
R
K
S
T
T
P
C
M
V
L
A
Site 3
T9
A
S
R
R
K
S
T
T
P
C
M
V
L
A
S
Site 4
S16
T
P
C
M
V
L
A
S
E
Q
D
P
D
L
E
Site 5
S26
D
P
D
L
E
L
I
S
D
L
D
E
G
P
P
Site 6
T36
D
E
G
P
P
V
L
T
P
V
E
N
T
R
A
Site 7
S45
V
E
N
T
R
A
E
S
I
S
S
D
E
E
V
Site 8
S47
N
T
R
A
E
S
I
S
S
D
E
E
V
H
E
Site 9
S48
T
R
A
E
S
I
S
S
D
E
E
V
H
E
S
Site 10
S55
S
D
E
E
V
H
E
S
V
D
S
D
N
Q
Q
Site 11
S58
E
V
H
E
S
V
D
S
D
N
Q
Q
N
K
K
Site 12
Y70
N
K
K
V
E
G
G
Y
E
C
K
Y
C
T
F
Site 13
Y74
E
G
G
Y
E
C
K
Y
C
T
F
Q
T
P
D
Site 14
Y114
C
N
F
L
T
K
R
Y
D
A
L
S
E
H
N
Site 15
S118
T
K
R
Y
D
A
L
S
E
H
N
L
K
Y
H
Site 16
Y124
L
S
E
H
N
L
K
Y
H
P
G
E
E
N
F
Site 17
T152
E
Q
T
I
N
D
L
T
F
D
G
S
F
V
K
Site 18
S156
N
D
L
T
F
D
G
S
F
V
K
E
E
N
A
Site 19
S168
E
N
A
E
Q
A
E
S
T
E
V
S
S
S
G
Site 20
T169
N
A
E
Q
A
E
S
T
E
V
S
S
S
G
I
Site 21
S172
Q
A
E
S
T
E
V
S
S
S
G
I
S
I
S
Site 22
S174
E
S
T
E
V
S
S
S
G
I
S
I
S
K
T
Site 23
S179
S
S
S
G
I
S
I
S
K
T
P
I
M
K
M
Site 24
T181
S
G
I
S
I
S
K
T
P
I
M
K
M
M
K
Site 25
S202
R
I
A
V
H
H
N
S
V
E
D
V
P
E
E
Site 26
S226
E
E
I
V
E
N
P
S
S
S
A
S
E
S
N
Site 27
S227
E
I
V
E
N
P
S
S
S
A
S
E
S
N
T
Site 28
S228
I
V
E
N
P
S
S
S
A
S
E
S
N
T
S
Site 29
S230
E
N
P
S
S
S
A
S
E
S
N
T
S
T
S
Site 30
S232
P
S
S
S
A
S
E
S
N
T
S
T
S
I
V
Site 31
T234
S
S
A
S
E
S
N
T
S
T
S
I
V
N
R
Site 32
S235
S
A
S
E
S
N
T
S
T
S
I
V
N
R
I
Site 33
T236
A
S
E
S
N
T
S
T
S
I
V
N
R
I
H
Site 34
S237
S
E
S
N
T
S
T
S
I
V
N
R
I
H
P
Site 35
T246
V
N
R
I
H
P
S
T
A
S
T
V
V
T
P
Site 36
Y289
P
V
N
S
I
P
T
Y
N
A
A
L
D
N
N
Site 37
T302
N
N
P
L
L
L
N
T
Y
N
K
F
P
Y
P
Site 38
Y303
N
P
L
L
L
N
T
Y
N
K
F
P
Y
P
T
Site 39
Y308
N
T
Y
N
K
F
P
Y
P
T
M
S
E
I
T
Site 40
S318
M
S
E
I
T
V
L
S
A
Q
A
K
Y
T
E
Site 41
S342
Q
R
L
K
H
G
V
S
W
T
P
E
E
V
E
Site 42
T344
L
K
H
G
V
S
W
T
P
E
E
V
E
E
A
Site 43
T359
R
R
K
Q
F
N
G
T
V
H
T
V
P
Q
T
Site 44
S422
L
T
V
A
G
V
P
S
Q
N
N
I
Q
K
S
Site 45
S429
S
Q
N
N
I
Q
K
S
Q
V
P
A
A
Q
P
Site 46
S450
A
T
A
A
V
P
T
S
Q
S
V
K
H
E
T
Site 47
S452
A
A
V
P
T
S
Q
S
V
K
H
E
T
A
L
Site 48
S464
T
A
L
V
N
P
D
S
F
G
I
R
A
K
K
Site 49
S482
Q
L
A
E
L
K
V
S
Y
L
K
N
Q
F
P
Site 50
S492
K
N
Q
F
P
H
D
S
E
I
I
R
L
M
K
Site 51
Y517
K
W
F
S
D
T
R
Y
N
Q
R
N
S
K
S
Site 52
S535
L
H
L
N
N
D
S
S
T
T
I
I
I
D
S
Site 53
S542
S
T
T
I
I
I
D
S
S
D
E
T
T
E
S
Site 54
S543
T
T
I
I
I
D
S
S
D
E
T
T
E
S
P
Site 55
T546
I
I
D
S
S
D
E
T
T
E
S
P
T
V
G
Site 56
T547
I
D
S
S
D
E
T
T
E
S
P
T
V
G
T
Site 57
S549
S
S
D
E
T
T
E
S
P
T
V
G
T
A
Q
Site 58
S560
G
T
A
Q
P
K
Q
S
W
N
P
F
P
D
F
Site 59
T568
W
N
P
F
P
D
F
T
P
Q
K
F
K
E
K
Site 60
S590
L
Q
A
S
F
L
N
S
S
V
L
T
D
E
E
Site 61
S591
Q
A
S
F
L
N
S
S
V
L
T
D
E
E
L
Site 62
T594
F
L
N
S
S
V
L
T
D
E
E
L
N
R
L
Site 63
T605
L
N
R
L
R
A
Q
T
K
L
T
R
R
E
I
Site 64
S622
W
F
T
E
K
K
K
S
K
A
L
K
E
E
K
Site 65
S635
E
K
M
E
I
D
E
S
N
A
G
S
S
K
E
Site 66
S639
I
D
E
S
N
A
G
S
S
K
E
E
A
G
E
Site 67
T647
S
K
E
E
A
G
E
T
S
P
A
D
E
S
G
Site 68
S648
K
E
E
A
G
E
T
S
P
A
D
E
S
G
A
Site 69
S653
E
T
S
P
A
D
E
S
G
A
P
K
S
G
S
Site 70
S658
D
E
S
G
A
P
K
S
G
S
T
G
K
I
C
Site 71
S660
S
G
A
P
K
S
G
S
T
G
K
I
C
K
K
Site 72
T668
T
G
K
I
C
K
K
T
P
E
Q
L
H
M
L
Site 73
T682
L
K
S
A
F
V
R
T
Q
W
P
S
P
E
E
Site 74
S686
F
V
R
T
Q
W
P
S
P
E
E
Y
D
K
L
Site 75
Y690
Q
W
P
S
P
E
E
Y
D
K
L
A
K
E
S
Site 76
T702
K
E
S
G
L
A
R
T
D
I
V
S
W
F
G
Site 77
S706
L
A
R
T
D
I
V
S
W
F
G
D
T
R
Y
Site 78
Y713
S
W
F
G
D
T
R
Y
A
W
K
N
G
N
L
Site 79
Y723
K
N
G
N
L
K
W
Y
Y
Y
Y
Q
S
A
N
Site 80
Y724
N
G
N
L
K
W
Y
Y
Y
Y
Q
S
A
N
S
Site 81
Y725
G
N
L
K
W
Y
Y
Y
Y
Q
S
A
N
S
S
Site 82
Y726
N
L
K
W
Y
Y
Y
Y
Q
S
A
N
S
S
S
Site 83
S732
Y
Y
Q
S
A
N
S
S
S
M
N
G
L
S
S
Site 84
S733
Y
Q
S
A
N
S
S
S
M
N
G
L
S
S
L
Site 85
S738
S
S
S
M
N
G
L
S
S
L
R
K
R
G
R
Site 86
S739
S
S
M
N
G
L
S
S
L
R
K
R
G
R
G
Site 87
S763
P
R
G
R
P
R
G
S
K
R
I
N
N
W
D
Site 88
S774
N
N
W
D
R
G
P
S
L
I
K
F
K
T
G
Site 89
T780
P
S
L
I
K
F
K
T
G
T
A
I
L
K
D
Site 90
T782
L
I
K
F
K
T
G
T
A
I
L
K
D
Y
Y
Site 91
Y788
G
T
A
I
L
K
D
Y
Y
L
K
H
K
F
L
Site 92
Y789
T
A
I
L
K
D
Y
Y
L
K
H
K
F
L
N
Site 93
S807
L
D
E
L
V
N
K
S
H
M
G
Y
E
Q
V
Site 94
Y811
V
N
K
S
H
M
G
Y
E
Q
V
R
E
W
F
Site 95
S825
F
A
E
R
Q
R
R
S
E
L
G
I
E
L
F
Site 96
S855
D
E
E
E
T
D
D
S
D
T
W
E
P
P
R
Site 97
T857
E
E
T
D
D
S
D
T
W
E
P
P
R
H
V
Site 98
S869
R
H
V
K
R
K
L
S
K
S
D
D
_
_
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation