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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
SART2
Full Name:
Dermatan-sulfate epimerase precursor
Alias:
Dermatan sulfate epimerase; DSE; DSEPI; SART-2; Squamous cell carcinoma antigen recognized by T cells 2
Type:
Glycan Metabolism - chondroitin sulfate biosynthesis; EC 5.1.3.19; Isomerase; Endoplasmic reticulum
Mass (Da):
109773
Number AA:
958
UniProt ID:
Q9UL01
International Prot ID:
IPI00002526
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005794
GO:0005783
GO:0016021
Uniprot
OncoNet
Molecular Function:
GO:0047757
PhosphoSite+
KinaseNET
Biological Process:
GO:0030208
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
Y40
I
P
F
T
N
A
N
Y
D
S
H
P
M
L
Y
Site 2
Y47
Y
D
S
H
P
M
L
Y
F
S
R
A
E
V
A
Site 3
S49
S
H
P
M
L
Y
F
S
R
A
E
V
A
E
L
Site 4
S62
E
L
Q
L
R
A
A
S
S
H
E
H
I
A
A
Site 5
S63
L
Q
L
R
A
A
S
S
H
E
H
I
A
A
R
Site 6
T77
R
L
T
E
A
V
H
T
M
L
S
S
P
L
E
Site 7
Y85
M
L
S
S
P
L
E
Y
L
P
P
W
D
P
K
Site 8
Y94
P
P
W
D
P
K
D
Y
S
A
R
W
N
E
I
Site 9
Y129
A
R
D
M
A
K
D
Y
M
E
R
M
A
A
Q
Site 10
Y166
A
T
A
Y
D
F
L
Y
N
Y
L
S
K
T
Q
Site 11
Y168
A
Y
D
F
L
Y
N
Y
L
S
K
T
Q
Q
E
Site 12
Y189
A
N
A
S
G
Y
M
Y
E
T
S
Y
R
R
G
Site 13
Y193
G
Y
M
Y
E
T
S
Y
R
R
G
W
G
F
Q
Site 14
Y230
Q
G
Y
L
Q
E
A
Y
L
W
T
K
Q
V
L
Site 15
S254
L
R
E
V
T
D
G
S
L
Y
E
G
V
A
Y
Site 16
Y256
E
V
T
D
G
S
L
Y
E
G
V
A
Y
G
S
Site 17
Y261
S
L
Y
E
G
V
A
Y
G
S
Y
T
T
R
S
Site 18
S263
Y
E
G
V
A
Y
G
S
Y
T
T
R
S
L
F
Site 19
Y264
E
G
V
A
Y
G
S
Y
T
T
R
S
L
F
Q
Site 20
T265
G
V
A
Y
G
S
Y
T
T
R
S
L
F
Q
Y
Site 21
Y272
T
T
R
S
L
F
Q
Y
M
F
L
V
Q
R
H
Site 22
Y316
V
A
I
A
D
S
N
Y
N
W
F
Y
G
P
E
Site 23
Y320
D
S
N
Y
N
W
F
Y
G
P
E
S
Q
L
V
Site 24
S338
K
F
V
M
R
N
G
S
G
N
W
L
A
D
Q
Site 25
T357
R
V
V
E
G
P
G
T
P
S
K
G
Q
R
W
Site 26
S359
V
E
G
P
G
T
P
S
K
G
Q
R
W
C
T
Site 27
Y374
L
H
T
E
F
L
W
Y
D
G
S
L
K
S
V
Site 28
S377
E
F
L
W
Y
D
G
S
L
K
S
V
P
P
P
Site 29
S380
W
Y
D
G
S
L
K
S
V
P
P
P
D
F
G
Site 30
T388
V
P
P
P
D
F
G
T
P
T
L
H
Y
F
E
Site 31
S413
L
P
A
E
I
N
R
S
F
L
S
F
K
S
G
Site 32
S416
E
I
N
R
S
F
L
S
F
K
S
G
K
L
G
Site 33
S419
R
S
F
L
S
F
K
S
G
K
L
G
G
R
A
Site 34
Y428
K
L
G
G
R
A
I
Y
D
I
V
H
R
N
K
Site 35
S457
H
E
H
P
D
Q
N
S
F
T
F
A
P
N
G
Site 36
T459
H
P
D
Q
N
S
F
T
F
A
P
N
G
V
P
Site 37
Y477
E
A
L
Y
G
P
K
Y
T
F
F
N
N
V
L
Site 38
T503
S
P
W
V
G
Q
V
T
E
D
C
S
S
K
W
Site 39
S507
G
Q
V
T
E
D
C
S
S
K
W
S
K
Y
K
Site 40
Y545
R
G
E
G
V
G
A
Y
N
P
Q
L
N
L
K
Site 41
S578
Q
I
H
L
G
E
E
S
P
L
E
T
A
A
S
Site 42
T582
G
E
E
S
P
L
E
T
A
A
S
F
F
H
N
Site 43
Y614
I
R
Q
R
D
G
L
Y
K
M
Y
W
M
D
D
Site 44
Y617
R
D
G
L
Y
K
M
Y
W
M
D
D
T
G
Y
Site 45
T622
K
M
Y
W
M
D
D
T
G
Y
S
E
K
A
T
Site 46
Y624
Y
W
M
D
D
T
G
Y
S
E
K
A
T
F
A
Site 47
S625
W
M
D
D
T
G
Y
S
E
K
A
T
F
A
S
Site 48
T629
T
G
Y
S
E
K
A
T
F
A
S
V
T
Y
P
Site 49
T634
K
A
T
F
A
S
V
T
Y
P
R
G
Y
P
Y
Site 50
Y635
A
T
F
A
S
V
T
Y
P
R
G
Y
P
Y
N
Site 51
Y639
S
V
T
Y
P
R
G
Y
P
Y
N
G
T
N
Y
Site 52
Y646
Y
P
Y
N
G
T
N
Y
V
N
V
T
M
H
L
Site 53
S655
N
V
T
M
H
L
R
S
P
I
T
R
A
A
Y
Site 54
S673
G
P
S
I
D
V
Q
S
F
T
V
H
G
D
S
Site 55
T675
S
I
D
V
Q
S
F
T
V
H
G
D
S
Q
Q
Site 56
Y694
I
A
T
S
K
H
A
Y
A
T
Y
L
W
T
G
Site 57
Y697
S
K
H
A
Y
A
T
Y
L
W
T
G
E
A
T
Site 58
S729
D
R
N
S
A
I
K
S
S
I
V
P
E
V
K
Site 59
S730
R
N
S
A
I
K
S
S
I
V
P
E
V
K
D
Site 60
S762
L
L
E
K
Q
I
L
S
R
V
R
N
T
A
S
Site 61
T767
I
L
S
R
V
R
N
T
A
S
F
R
K
T
A
Site 62
S769
S
R
V
R
N
T
A
S
F
R
K
T
A
E
R
Site 63
T773
N
T
A
S
F
R
K
T
A
E
R
L
L
R
F
Site 64
S781
A
E
R
L
L
R
F
S
D
K
R
Q
T
E
E
Site 65
T786
R
F
S
D
K
R
Q
T
E
E
A
I
D
R
I
Site 66
S797
I
D
R
I
F
A
I
S
Q
Q
Q
Q
Q
Q
S
Site 67
S804
S
Q
Q
Q
Q
Q
Q
S
K
S
K
K
N
R
R
Site 68
S806
Q
Q
Q
Q
Q
S
K
S
K
K
N
R
R
A
G
Site 69
Y816
N
R
R
A
G
K
R
Y
K
F
V
D
A
V
P
Site 70
T866
L
L
D
F
A
D
V
T
Y
E
K
H
K
N
G
Site 71
Y867
L
D
F
A
D
V
T
Y
E
K
H
K
N
G
G
Site 72
T887
F
G
Q
A
R
M
V
T
T
T
H
S
R
A
P
Site 73
T889
Q
A
R
M
V
T
T
T
H
S
R
A
P
S
L
Site 74
S891
R
M
V
T
T
T
H
S
R
A
P
S
L
S
A
Site 75
S895
T
T
H
S
R
A
P
S
L
S
A
S
Y
T
R
Site 76
S897
H
S
R
A
P
S
L
S
A
S
Y
T
R
L
F
Site 77
S928
T
Y
F
Q
R
A
Q
S
L
H
G
Q
R
C
L
Site 78
Y936
L
H
G
Q
R
C
L
Y
A
V
L
L
I
D
S
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation