KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
DrugProNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
Home
|
Kinexus
|
Contact
|
Credits
Protein Info
Short Name:
TBX21
Full Name:
T-box transcription factor TBX21
Alias:
TBET; T-bet; TBLYM; T-box 21; T-box protein 21; T-cell-specific T-box transcription factor T-bet; Transcription factor TBLYM
Type:
Transcription protein
Mass (Da):
58328
Number AA:
535
UniProt ID:
Q9UL17
International Prot ID:
IPI00007732
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005634
Uniprot
OncoNet
Molecular Function:
GO:0003700
PhosphoSite+
KinaseNET
Biological Process:
GO:0007275
GO:0006355
GO:0006350
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T13
P
G
C
G
D
M
L
T
G
T
E
P
M
P
G
Site 2
T15
C
G
D
M
L
T
G
T
E
P
M
P
G
S
D
Site 3
S21
G
T
E
P
M
P
G
S
D
E
G
R
A
P
G
Site 4
Y35
G
A
D
P
Q
H
R
Y
F
Y
P
E
P
G
A
Site 5
Y37
D
P
Q
H
R
Y
F
Y
P
E
P
G
A
Q
D
Site 6
S53
D
E
R
R
G
G
G
S
L
G
S
P
Y
P
G
Site 7
S56
R
G
G
G
S
L
G
S
P
Y
P
G
G
A
L
Site 8
Y58
G
G
S
L
G
S
P
Y
P
G
G
A
L
V
P
Site 9
Y75
P
S
R
F
L
G
A
Y
A
Y
P
P
R
P
Q
Site 10
Y77
R
F
L
G
A
Y
A
Y
P
P
R
P
Q
A
A
Site 11
S92
G
F
P
G
A
G
E
S
F
P
P
P
A
D
A
Site 12
Y102
P
P
A
D
A
E
G
Y
Q
P
G
E
G
Y
A
Site 13
Y108
G
Y
Q
P
G
E
G
Y
A
A
P
D
P
R
A
Site 14
Y118
P
D
P
R
A
G
L
Y
P
G
P
R
E
D
Y
Site 15
Y125
Y
P
G
P
R
E
D
Y
A
L
P
A
G
L
E
Site 16
S181
V
A
G
L
E
P
T
S
H
Y
R
M
F
V
D
Site 17
S213
Q
C
G
K
A
E
G
S
M
P
G
N
R
L
Y
Site 18
Y220
S
M
P
G
N
R
L
Y
V
H
P
D
S
P
N
Site 19
S225
R
L
Y
V
H
P
D
S
P
N
T
G
A
H
W
Site 20
S238
H
W
M
R
Q
E
V
S
F
G
K
L
K
L
T
Site 21
T245
S
F
G
K
L
K
L
T
N
N
K
G
A
S
N
Site 22
S251
L
T
N
N
K
G
A
S
N
N
V
T
Q
M
I
Site 23
T255
K
G
A
S
N
N
V
T
Q
M
I
V
L
Q
S
Site 24
S262
T
Q
M
I
V
L
Q
S
L
H
K
Y
Q
P
R
Site 25
Y266
V
L
Q
S
L
H
K
Y
Q
P
R
L
H
I
V
Site 26
T293
A
S
N
T
H
I
F
T
F
Q
E
T
Q
F
I
Site 27
T297
H
I
F
T
F
Q
E
T
Q
F
I
A
V
T
A
Site 28
Y305
Q
F
I
A
V
T
A
Y
Q
N
A
E
I
T
Q
Site 29
S330
G
F
R
E
N
F
E
S
M
Y
T
S
V
D
T
Site 30
Y332
R
E
N
F
E
S
M
Y
T
S
V
D
T
S
I
Site 31
T333
E
N
F
E
S
M
Y
T
S
V
D
T
S
I
P
Site 32
S334
N
F
E
S
M
Y
T
S
V
D
T
S
I
P
S
Site 33
T337
S
M
Y
T
S
V
D
T
S
I
P
S
P
P
G
Site 34
S338
M
Y
T
S
V
D
T
S
I
P
S
P
P
G
P
Site 35
S341
S
V
D
T
S
I
P
S
P
P
G
P
N
C
Q
Site 36
Y355
Q
F
L
G
G
D
H
Y
S
P
L
L
P
N
Q
Site 37
S356
F
L
G
G
D
H
Y
S
P
L
L
P
N
Q
Y
Site 38
Y363
S
P
L
L
P
N
Q
Y
P
V
P
S
R
F
Y
Site 39
Y370
Y
P
V
P
S
R
F
Y
P
D
L
P
G
Q
A
Site 40
S394
L
G
A
P
R
D
H
S
Y
E
A
E
F
R
A
Site 41
Y395
G
A
P
R
D
H
S
Y
E
A
E
F
R
A
V
Site 42
S411
M
K
P
A
F
L
P
S
A
P
G
P
T
M
S
Site 43
S418
S
A
P
G
P
T
M
S
Y
Y
R
G
Q
E
V
Site 44
Y419
A
P
G
P
T
M
S
Y
Y
R
G
Q
E
V
L
Site 45
Y420
P
G
P
T
M
S
Y
Y
R
G
Q
E
V
L
A
Site 46
Y438
G
W
P
V
A
P
Q
Y
P
P
K
M
G
P
A
Site 47
S446
P
P
K
M
G
P
A
S
W
F
R
P
M
R
T
Site 48
T453
S
W
F
R
P
M
R
T
L
P
M
E
P
G
P
Site 49
S463
M
E
P
G
P
G
G
S
E
G
R
G
P
E
D
Site 50
S487
I
A
P
I
R
P
E
S
S
D
S
G
L
G
E
Site 51
S488
A
P
I
R
P
E
S
S
D
S
G
L
G
E
G
Site 52
S490
I
R
P
E
S
S
D
S
G
L
G
E
G
D
S
Site 53
S497
S
G
L
G
E
G
D
S
K
R
R
R
V
S
P
Site 54
S503
D
S
K
R
R
R
V
S
P
Y
P
S
S
G
D
Site 55
Y505
K
R
R
R
V
S
P
Y
P
S
S
G
D
S
S
Site 56
S507
R
R
V
S
P
Y
P
S
S
G
D
S
S
S
P
Site 57
S508
R
V
S
P
Y
P
S
S
G
D
S
S
S
P
A
Site 58
S511
P
Y
P
S
S
G
D
S
S
S
P
A
G
A
P
Site 59
S512
Y
P
S
S
G
D
S
S
S
P
A
G
A
P
S
Site 60
S513
P
S
S
G
D
S
S
S
P
A
G
A
P
S
P
Site 61
S519
S
S
P
A
G
A
P
S
P
F
D
K
E
A
E
Site 62
Y530
K
E
A
E
G
Q
F
Y
N
Y
F
P
N
_
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation